ketoconazole has been researched along with Nephrotic Syndrome in 3 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The co-administration of ketoconazole to CsA in children with idiopathic steroid-dependent nephrotic syndrome safely results in a significant reduction in CsA cost, which causes great concern in developing countries." | 7.73 | Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome. ( Donia, A; El-Basuony, F; El-Husseini, A; Hassan, N; Mahmoud, I; Sabry, A; Sayed-Ahmad, N; Sheashaa, H; Sobh, M, 2006) |
| " Patients who received CsA and ketoconazole were comparable with those who received CsA alone regarding age, sex, duration of renal disease, renal pathology, severity of nephrotic syndrome, renal function, hepatic function and steroid response." | 7.72 | Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome. ( Donia, A; El-Basuony, F; El-Husseini, A; Hassan, N; Mahmoud, I; Sayed-Ahmad, N; Sobh, M, 2004) |
| "The co-administration of ketoconazole to CsA in children with idiopathic steroid-dependent nephrotic syndrome safely results in a significant reduction in CsA cost, which causes great concern in developing countries." | 3.73 | Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome. ( Donia, A; El-Basuony, F; El-Husseini, A; Hassan, N; Mahmoud, I; Sabry, A; Sayed-Ahmad, N; Sheashaa, H; Sobh, M, 2006) |
| "The concomitant use of cyclosporine (CsA) and ketoconazole (keto) in children with nephrotic syndrome (NS) has never been reported in the literature." | 3.72 | Co-administration of cyclosporine and ketoconazole in idiopathic childhood nephrosis. ( Donia, A; el-Basuony, F; el-Husseini, A; Hassan, N; Mahmoud, I; Sayed-Ahmad, N; Sobh, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Husseini, A | 3 |
| El-Basuony, F | 3 |
| Donia, A | 3 |
| Mahmoud, I | 3 |
| Hassan, N | 3 |
| Sayed-Ahmad, N | 3 |
| Sobh, M | 3 |
| Sheashaa, H | 1 |
| Sabry, A | 1 |
3 other studies available for ketoconazole and Nephrotic Syndrome
| Article | Year |
|---|---|
Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antifungal Agents; Child; Cyclosporine; Drug Synergism; | 2004 |
Co-administration of cyclosporine and ketoconazole in idiopathic childhood nephrosis.
Topics: Child; Child, Preschool; Cohort Studies; Costs and Cost Analysis; Cyclosporine; Drug Interactions; D | 2004 |
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome.
Topics: Adolescent; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Cyclospori | 2006 |