ketoconazole has been researched along with Multiple Myeloma in 6 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zygomycosis is an opportunistic fungal infection that is increasingly reported in hematological patients." | 2.42 | Improved outcome of zygomycosis in patients with hematological diseases? ( Anagnostopolous, I; Gleissner, B; Schilling, A; Siehl, I; Thiel, E, 2004) |
| "A report on a patient with multiple myeloma, undergoing bone marrow transplant, who developed systemic fungal infection due to Candida krusei after bone marrow transplantation." | 1.29 | Changing pattern of Candida species in a bone marrow transplant patient. ( Banerjee, U; Fotedar, R, 1996) |
| " The half-life of ketoconazole was 3." | 1.27 | Ketoconazole pharmacokinetics during chronic dosing in adults with haematological malignancy. ( Bredow, MT; Daneshmend, TK; Richardson, MD; Slade, RR; Stockley, RJ; Warnock, DW, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, V | 1 |
| Zepeda, G | 1 |
| Alvareda, D | 1 |
| Gleissner, B | 1 |
| Schilling, A | 1 |
| Anagnostopolous, I | 1 |
| Siehl, I | 1 |
| Thiel, E | 1 |
| Pérusse, R | 1 |
| Muindi, JR | 1 |
| Young, CW | 1 |
| Warrell, RP | 1 |
| Fotedar, R | 1 |
| Banerjee, U | 1 |
| Stockley, RJ | 1 |
| Daneshmend, TK | 1 |
| Bredow, MT | 1 |
| Warnock, DW | 1 |
| Richardson, MD | 1 |
| Slade, RR | 1 |
2 reviews available for ketoconazole and Multiple Myeloma
| Article | Year |
|---|---|
Improved outcome of zygomycosis in patients with hematological diseases?
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspe | 2004 |
Clinical pharmacology of all-trans retinoic acid.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Lung Neoplasms | 1994 |
4 other studies available for ketoconazole and Multiple Myeloma
| Article | Year |
|---|---|
[Nosocomial urinary infection due to Trichosporon asahii. First two cases in Chile].
Topics: Amphotericin B; Antifungal Agents; Chile; Communicable Diseases, Emerging; Cross Infection; Drug Res | 2003 |
Oral candidiasis and multiple myeloma. An unusual association.
Topics: Candidiasis, Oral; Female; Humans; Immunocompromised Host; Ketoconazole; Middle Aged; Multiple Myelo | 1994 |
Changing pattern of Candida species in a bone marrow transplant patient.
Topics: Adult; Antifungal Agents; Bone Marrow Transplantation; Candidiasis; Drug Resistance, Microbial; Fung | 1996 |
Ketoconazole pharmacokinetics during chronic dosing in adults with haematological malignancy.
Topics: Adult; Drug Administration Schedule; Female; Half-Life; Humans; Immune Tolerance; Ketoconazole; Kine | 1986 |