ketoconazole has been researched along with Lung Neoplasms in 24 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 7.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 7.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma." | 7.67 | Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989) |
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 3.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the efficacy of fluconazole as an alternative treatment for controlling hypercortisolism in Cushing's syndrome and to determine its effect on glucocorticoid production in vitro." | 3.73 | Long term control of hypercortisolism with fluconazole: case report and in vitro studies. ( Luger, A; Maier, C; Nowotny, P; Riedl, M; Schima, W; Zettinig, G, 2006) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 3.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma." | 3.67 | Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989) |
| " However, continuous oral dosing results in progressive decline in plasma drug concentrations, which is associated with relapse and resistance to this retinoid." | 2.67 | Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole. ( DeGrazia, F; Francis, PA; Huselton, C; Kris, MG; Muindi, JR; Orazem, JP; Rigas, JR; Warrell, RP; Young, CW, 1993) |
| "Unfortunately the patient died of respiratory failure due to metastasis." | 1.37 | [Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma]. ( Montes-Mollón, MÁ; Paz Moreno-Arrones, J, 2011) |
| "We report the case of a patient with prostate cancer who develops mediastinal lymphadenopathy, pulmonary nodules and cutaneous metastases 8 years after the diagnosis." | 1.34 | [Mediastinal lymph nodes during the course of a metastatic prostate cancer]. ( Aguilera Tubet, C; Ballestero Diego, R; Roca Edreira, A; Villanueva Peña, A; Zubillaga Guerrero, S, 2007) |
| "Cushing's syndrome is infrequently associated with adenocarcinomas of the lung." | 1.30 | [Paraneoplastic hypercorticism associated with a bronchial adenocarcinoma]. ( Chaouat, A; Kessler, R; Schott, R; Tavernier, M; Weitzenblum, E, 1999) |
| "Six to 10 months after hypercorticism was cured with ketoconazole and bilateral adrenalectomy, a thymic mass 2 to 5 cm in length was detected by computerized tomography or magnetic resonance imaging in all 3 patients." | 1.29 | [Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases]. ( Caillé, JM; Catargi, B; Drouillard, J; Greselle, JF; Laurent, F; Martigne, C; Roger, P; Tabarin, A, 1993) |
| "Treatment with ketoconazole (KCZ) resulted in significant suppression of serum cortisol levels." | 1.28 | The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome. ( Brigham, B; Hoffman, DM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.67) | 18.7374 |
| 1990's | 12 (50.00) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arun, Y | 1 |
| Bhaskar, G | 1 |
| Balachandran, C | 1 |
| Ignacimuthu, S | 1 |
| Perumal, PT | 1 |
| Ilie, MD | 1 |
| Raverot, V | 1 |
| Tronc, F | 1 |
| Vasiljevic, A | 1 |
| Borson-Chazot, F | 1 |
| Raverot, G | 1 |
| Aggarwal, R | 1 |
| Halabi, S | 1 |
| Kelly, WK | 1 |
| George, D | 1 |
| Mahoney, JF | 1 |
| Millard, F | 1 |
| Stadler, WM | 1 |
| Morris, MJ | 1 |
| Kantoff, P | 1 |
| Monk, JP | 1 |
| Carducci, M | 1 |
| Small, EJ | 1 |
| George, JC | 1 |
| Vedamurthy, D | 1 |
| Bermudez, M | 1 |
| Kennedy, JW | 1 |
| Izzedine, H | 1 |
| Besse, B | 1 |
| Lazareth, A | 1 |
| Bourry, EF | 1 |
| Soria, JC | 1 |
| Paz Moreno-Arrones, J | 1 |
| Montes-Mollón, MÁ | 1 |
| Riedl, M | 1 |
| Maier, C | 1 |
| Zettinig, G | 1 |
| Nowotny, P | 1 |
| Schima, W | 1 |
| Luger, A | 1 |
| Roca Edreira, A | 1 |
| Aguilera Tubet, C | 1 |
| Villanueva Peña, A | 1 |
| Ballestero Diego, R | 1 |
| Zubillaga Guerrero, S | 1 |
| Winquist, EW | 1 |
| Laskey, J | 2 |
| Crump, M | 1 |
| Khamsi, F | 2 |
| Shepherd, FA | 3 |
| Muindi, JR | 2 |
| Young, CW | 2 |
| Warrell, RP | 2 |
| Mawer, EB | 1 |
| Hayes, ME | 1 |
| Heys, SE | 1 |
| Davies, M | 1 |
| White, A | 1 |
| Stewart, MF | 1 |
| Smith, GN | 1 |
| Tabarin, A | 1 |
| Catargi, B | 1 |
| Laurent, F | 1 |
| Greselle, JF | 1 |
| Martigne, C | 1 |
| Caillé, JM | 1 |
| Drouillard, J | 1 |
| Roger, P | 1 |
| Rigas, JR | 1 |
| Francis, PA | 1 |
| Kris, MG | 1 |
| Huselton, C | 1 |
| DeGrazia, F | 1 |
| Orazem, JP | 1 |
| Schott, R | 1 |
| Chaouat, A | 1 |
| Tavernier, M | 1 |
| Kessler, R | 1 |
| Weitzenblum, E | 1 |
| Evans, WK | 2 |
| Goss, PE | 1 |
| Johansen, E | 1 |
| Niimi, T | 1 |
| Kajita, M | 1 |
| Saito, H | 1 |
| Hoffman, DM | 1 |
| Brigham, B | 1 |
| Milleron, B | 1 |
| Roger, V | 1 |
| Roux, P | 1 |
| Lebreton, C | 1 |
| Koeger, A | 1 |
| Dupont, B | 1 |
| Akoun, G | 1 |
| Kruimel, JW | 1 |
| Smals, AG | 1 |
| Beex, LV | 1 |
| Swinkels, LM | 1 |
| Pieters, GF | 1 |
| Kloppenborg, PW | 1 |
| Impens, N | 1 |
| De Greve, J | 1 |
| De Beule, K | 1 |
| Meysman, M | 1 |
| De Beuckelaere, S | 1 |
| Schandevyl, W | 1 |
| Contreras, P | 1 |
| Rojas, A | 1 |
| Biagini, L | 1 |
| González, P | 1 |
| Massardo, T | 1 |
| Bhadoria, DP | 1 |
| Mukhopadhyay, DK | 1 |
| Mehta, S | 1 |
| Mittal, D | 1 |
| Rao, YV | 1 |
| Malhotra, KK | 1 |
| Hoffert, B | 1 |
| Emery, G | 1 |
| Trachtenberg, J | 1 |
| Nardone, PA | 1 |
| Slotman, GJ | 1 |
| Vezeridis, MP | 1 |
2 reviews available for ketoconazole and Lung Neoplasms
| Article | Year |
|---|---|
Clinical pharmacology of all-trans retinoic acid.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Lung Neoplasms | 1994 |
[Semi-invasive aspergillosis with involvement of the thoracic wall cured by itraconazole].
Topics: Antifungal Agents; Aspergillosis; Carcinoma, Bronchogenic; Humans; Itraconazole; Ketoconazole; Lung | 1990 |
2 trials available for ketoconazole and Lung Neoplasms
| Article | Year |
|---|---|
The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (
Topics: Aged; Androgen Antagonists; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antineoplastic Com | 2013 |
Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole.
Topics: Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug | 1993 |
20 other studies available for ketoconazole and Lung Neoplasms
| Article | Year |
|---|---|
Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tum | 2013 |
Cabergoline in severe ectopic or occult Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cabergoline; Carcinoid Tumor; Cushing Syndrome; Dopamine Agonis | 2019 |
Quiz Page October 2016: Severe Hypokalemia, Metabolic Alkalosis, and Malignancy.
Topics: ACTH Syndrome, Ectopic; Alkalosis; Amiloride; Cytochrome P-450 CYP3A Inhibitors; Diabetes Insipidus; | 2016 |
Hypokalemia, metabolic alkalosis, and hypertension in a lung cancer patient.
Topics: Aged; Alkalosis; Cushing Syndrome; France; Humans; Hypertension; Hypokalemia; Ketoconazole; Lung Neo | 2009 |
[Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma].
Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aged; Antineoplastic Combined Chemotherapy | 2011 |
Long term control of hypercortisolism with fluconazole: case report and in vitro studies.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged, 80 and over; Antifungal Agents; Cell Line, Tu | 2006 |
[Mediastinal lymph nodes during the course of a metastatic prostate cancer].
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols; Bon | 2007 |
Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Carcinoma, Small Cell; Caus | 1995 |
Constitutive synthesis of 1,25-dihydroxyvitamin D3 by a human small cell lung cancer cell line.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcifediol; Calcitriol; Calcium; Carcinoma, Small Cell; C | 1994 |
[Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases].
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adult; Carcinoid Tumor; Cushing Syndrome; Drug Therapy, | 1993 |
[Paraneoplastic hypercorticism associated with a bronchial adenocarcinoma].
Topics: Adenocarcinoma; Aged; Antifungal Agents; Cushing Syndrome; Humans; Ketoconazole; Lung Neoplasms; Mal | 1999 |
Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Smal | 1992 |
Necrotizing bronchial aspergillosis in a patient receiving neoadjuvant chemotherapy for non-small cell lung carcinoma.
Topics: Aged; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus | 1991 |
The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome.
Topics: ACTH Syndrome, Ectopic; Carcinoma, Small Cell; Female; Humans; Ketoconazole; Lung Neoplasms; Middle | 1991 |
Favourable response of a virilizing adrenocortical carcinoma to preoperative treatment with ketoconazole and postoperative chemotherapy.
Topics: Adrenal Cortex Neoplasms; Adult; Aldehyde-Lyases; Androgens; Antineoplastic Combined Chemotherapy Pr | 1991 |
Oral treatment with itraconazole of aspergilloma in cavitary lung cancer.
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Carcinoma, Small Cell; Humans; Itraconazole | 1990 |
Regression of metastatic adrenal carcinoma during palliative ketoconazole treatment.
Topics: Adrenal Gland Neoplasms; Female; Humans; Ketoconazole; Lung Neoplasms; Middle Aged; Palliative Care | 1985 |
Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Bone Neoplasms; Disseminated Intravascular Coagulation; Emergencies; Humans; K | 1989 |
Ketoconazole. Use in the treatment of ectopic adrenocorticotropic hormone production and Cushing's syndrome in small-cell lung cancer.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoma, Small Cell; Cushing Syndrome; Humans; Hydro | 1985 |
Ketoconazole: a thromboxane synthetase and 5-lipoxygenase inhibitor with antimetastatic activity in B16-F10 melanoma.
Topics: Animals; Arachidonate Lipoxygenases; Ketoconazole; Lipoxygenase Inhibitors; Lung Neoplasms; Melanoma | 1988 |