ketoconazole has been researched along with Liver Cirrhosis in 7 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a previously healthy woman who developed liver cirrhosis as a sequela of acute hepatic injury that was induced by ketoconazole administration to treat onychomycosis." | 7.72 | Liver cirrhosis developed after ketoconazole-induced acute hepatic injury. ( Chang, R; Chang, YW; Dong, SH; Han, YS; Kim, BH; Kim, HJ; Kim, TH; Kim, YW; Lee, JI; Yang, DM, 2003) |
| " The first was a case of ketoconazole-induced hepatitis, and the second was a case of hepatitis C-related liver cirrhosis with hepatocellular carcinoma." | 7.71 | Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases. ( Chang, FY; Huang, DF; Huang, YH; Huang, YS; Huo, TI; Lee, SD; Lin, CC; Wu, JC, 2001) |
| "We describe a previously healthy woman who developed liver cirrhosis as a sequela of acute hepatic injury that was induced by ketoconazole administration to treat onychomycosis." | 3.72 | Liver cirrhosis developed after ketoconazole-induced acute hepatic injury. ( Chang, R; Chang, YW; Dong, SH; Han, YS; Kim, BH; Kim, HJ; Kim, TH; Kim, YW; Lee, JI; Yang, DM, 2003) |
| " The first was a case of ketoconazole-induced hepatitis, and the second was a case of hepatitis C-related liver cirrhosis with hepatocellular carcinoma." | 3.71 | Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases. ( Chang, FY; Huang, DF; Huang, YH; Huang, YS; Huo, TI; Lee, SD; Lin, CC; Wu, JC, 2001) |
| "Ketoconazole is a first orally available anti-fungal drug which has been reported as a potent inhibitor of human cytochrome P-450." | 1.51 | Hepatoprotective effect of ketoconazole in chronic liver injury model. ( Ahmed, M; Akhtar, U; Ali, G; Shehzad, U; Tayyeb, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akhtar, U | 1 |
| Ahmed, M | 1 |
| Tayyeb, A | 1 |
| Shehzad, U | 1 |
| Ali, G | 1 |
| Kim, TH | 1 |
| Kim, BH | 1 |
| Kim, YW | 1 |
| Yang, DM | 1 |
| Han, YS | 1 |
| Dong, SH | 1 |
| Kim, HJ | 1 |
| Chang, YW | 1 |
| Lee, JI | 1 |
| Chang, R | 1 |
| Lin, CC | 1 |
| Wu, JC | 1 |
| Huang, DF | 1 |
| Huang, YS | 1 |
| Huang, YH | 1 |
| Huo, TI | 1 |
| Chang, FY | 1 |
| Lee, SD | 1 |
| Andrés, A | 1 |
| Morales, JM | 1 |
| Farias, J | 1 |
| Hernandez, G | 1 |
| Gomez, M | 1 |
| Calleja, J | 1 |
| Moreno, E | 1 |
| Rodicio, JL | 1 |
| Martínez-Jordá, R | 1 |
| Rodriguez-Sasiain, JM | 1 |
| Suárez, E | 1 |
| Calvo, R | 1 |
| Kendrey, G | 1 |
| Kovács, M | 1 |
| Lake-Bakaar, G | 1 |
| Cameron, HA | 1 |
7 other studies available for ketoconazole and Liver Cirrhosis
| Article | Year |
|---|---|
Hepatoprotective effect of ketoconazole in chronic liver injury model.
Topics: Actins; Animals; Carbon Tetrachloride; Cell Death; Chemical and Drug Induced Liver Injury; Disease M | 2019 |
Liver cirrhosis developed after ketoconazole-induced acute hepatic injury.
Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Ketoconazole; Live | 2003 |
Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases.
Topics: Antifungal Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Hepati | 2001 |
Acute renal failure after liver transplantation in patients treated with cyclosporine.
Topics: Acute Kidney Injury; Adult; Candidiasis; Cyclosporine; Female; Humans; Ketoconazole; Liver Cirrhosis | 1992 |
Serum binding of ketoconazole in health and disease.
Topics: Adult; Blood Proteins; Female; Humans; Ketoconazole; Kidney Failure, Chronic; Liver Cirrhosis; Male; | 1990 |
[Histopathologic observations on acute liver lesions in patients taking Nizoralt (ketokonazol)].
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Ketoconazole; Liver; Liver Cirrhosis; | 1988 |
CSM update: adverse drug reactions and the liver.
Topics: Chemical and Drug Induced Liver Injury; Humans; Ketoconazole; Liver Cirrhosis | 1985 |