ketoconazole has been researched along with Leishmaniasis, Visceral in 20 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of a renal transplant recipient who developed pancreatitis during stibogluconate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported." | 7.68 | Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in a renal transplant recipient after the occurrence of pancreatitis due to stibogluconate. ( al-Eisa, A; Alfurayh, O; Damanhouri, G; Dammas, S; Halim, MA; Kalin, ME, 1993) |
| "Acute pancreatitis is a rarely reported adverse effect." | 5.31 | Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate. ( Bakirtaç, A; Kara, C; Kuyucu, N; Teziç, T, 2001) |
| "Amphotericin B is used for the treatment of systemic mycoses and visceral leishmaniasis." | 3.71 | No evidence of oxidant events in amphotericin B cytotoxicity versus L. infantum promastigotes. ( Azas, N; Delmas, F; Di Giorgio, C; Gasquet, M; Timon-David, P, 2001) |
| "A case of a renal transplant recipient who developed pancreatitis during stibogluconate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported." | 3.68 | Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in a renal transplant recipient after the occurrence of pancreatitis due to stibogluconate. ( al-Eisa, A; Alfurayh, O; Damanhouri, G; Dammas, S; Halim, MA; Kalin, ME, 1993) |
| " However, no serious side effect were noted in all of the patients during treatment." | 2.67 | The efficacy and safety of ketoconazole in visceral leishmaniasis. ( Gachihi, GS; Kirigi, G; Mbugua, J; Nyakundi, PM; Rashid, JR; Wasunna, KM, 1994) |
| "Acute pancreatitis is a rarely reported adverse effect." | 1.31 | Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate. ( Bakirtaç, A; Kara, C; Kuyucu, N; Teziç, T, 2001) |
| "Ketoconazole was shown to be effective against imported cutaneous leishmaniasis." | 1.30 | Imported cutaneous leishmaniasis in Thailand. ( Punpoowong, B; Riganti, M; Viravan, C; Viriyavejakul, P, 1997) |
| " orally in divided dosage for 30 days." | 1.29 | Combination therapy in Kala-azar. ( Jha, S; Jha, TK; Singh, IJ; Singh, NK, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (80.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castanys-Muñoz, E | 1 |
| Pérez-Victoria, JM | 1 |
| Gamarro, F | 1 |
| Castanys, S | 1 |
| Shakya, N | 1 |
| Sane, SA | 1 |
| Vishwakarma, P | 1 |
| Bajpai, P | 1 |
| Gupta, S | 1 |
| Ramesh, V | 2 |
| Mukherjee, A | 1 |
| Rashid, JR | 1 |
| Wasunna, KM | 1 |
| Gachihi, GS | 1 |
| Nyakundi, PM | 1 |
| Mbugua, J | 1 |
| Kirigi, G | 1 |
| Chandra, J | 1 |
| Patwari, AK | 1 |
| Halim, MA | 1 |
| Alfurayh, O | 1 |
| Kalin, ME | 1 |
| Dammas, S | 1 |
| al-Eisa, A | 1 |
| Damanhouri, G | 1 |
| Ahasan, HA | 1 |
| Rafiqueuddin, AK | 1 |
| Azhar, MA | 1 |
| Chowdhury, MA | 1 |
| Singh, NK | 2 |
| Jha, TK | 2 |
| Singh, IJ | 1 |
| Jha, S | 2 |
| Wali, JP | 3 |
| Aggarwal, P | 3 |
| Nandy, A | 1 |
| Singh, S | 3 |
| Addy, M | 1 |
| Guha, SK | 1 |
| Dwivedi, SN | 1 |
| Karmarkar, MG | 1 |
| Maji, AK | 1 |
| Viriyavejakul, P | 1 |
| Viravan, C | 1 |
| Riganti, M | 1 |
| Punpoowong, B | 1 |
| Hueso, M | 1 |
| Bover, J | 1 |
| Serón, D | 1 |
| Gil-Vernet, S | 1 |
| Rufí, G | 1 |
| Alsina, J | 1 |
| Grinyó, JM | 1 |
| Kuyucu, N | 1 |
| Kara, C | 1 |
| Bakirtaç, A | 1 |
| Teziç, T | 1 |
| Azas, N | 1 |
| Di Giorgio, C | 1 |
| Delmas, F | 1 |
| Gasquet, M | 1 |
| Timon-David, P | 1 |
| Lafeuillade, A | 1 |
| Chaffanjon, P | 1 |
| Delbeke, E | 1 |
| Quilichini, R | 1 |
| Zijlstra, EE | 1 |
| Saxena, U | 1 |
| Misra, RS | 1 |
| Gupta, U | 2 |
| Saluja, S | 2 |
| Andreo, JA | 1 |
| Vivancos, F | 1 |
| Serrano, P | 1 |
| Soriano, J | 1 |
2 reviews available for ketoconazole and Leishmaniasis, Visceral
| Article | Year |
|---|---|
Post-kala-azar dermal leishmaniasis.
Topics: Allopurinol; Amphotericin B; Antimony Sodium Gluconate; Humans; Incidence; Ketoconazole; Leishmanias | 1995 |
Diagnosis and treatment of kala-azar.
Topics: Allopurinol; Amphotericin B; Antimony Sodium Gluconate; Child; Combined Modality Therapy; Humans; Ke | 1994 |
4 trials available for ketoconazole and Leishmaniasis, Visceral
| Article | Year |
|---|---|
The efficacy and safety of ketoconazole in visceral leishmaniasis.
Topics: Administration, Oral; Adolescent; Adult; Body Weight; Child; Female; Hemoglobins; Humans; Ketoconazo | 1994 |
Ketoconazole in the treatment of visceral leishmaniasis (kala-azar)
Topics: Administration, Oral; Antiprotozoal Agents; Follow-Up Studies; Humans; Ketoconazole; Leishmaniasis, | 1996 |
Efficacy of sodium antimony gluconate and ketoconazole in the treatment of kala-azar--a comparative study.
Topics: Drug Monitoring; Follow-Up Studies; Hepatomegaly; Humans; Ketoconazole; Leishmaniasis, Visceral; Liv | 1997 |
The treatment of kala-azar: old and new options.
Topics: Amphotericin B; Antimony; Humans; Ketoconazole; Leishmaniasis, Visceral; Paromomycin | 1992 |
14 other studies available for ketoconazole and Leishmaniasis, Visceral
| Article | Year |
|---|---|
Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Base Sequence; Bi | 2008 |
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv.
Topics: Animals; Antiprotozoal Agents; Cinnamates; Cricetinae; Disease Models, Animal; Drug Therapy, Combina | 2011 |
Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in a renal transplant recipient after the occurrence of pancreatitis due to stibogluconate.
Topics: Adult; Allopurinol; Antimony Sodium Gluconate; Drug Therapy, Combination; Female; Humans; Ketoconazo | 1993 |
Combination therapy in Kala-azar.
Topics: Adult; Allopurinol; Antimony Sodium Gluconate; Antiprotozoal Agents; Dose-Response Relationship, Dru | 1995 |
Ketoconazole in antimonial unresponsive cases of Kala-azar.
Topics: Adult; Animals; Antifungal Agents; Antimony Sodium Gluconate; Antiprotozoal Agents; Drug Resistance; | 1995 |
Imported cutaneous leishmaniasis in Thailand.
Topics: Adult; Humans; Ketoconazole; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male; Retrospective | 1997 |
The renal transplant patient with visceral leishmaniasis who could not tolerate meglumine antimoniate-cure with ketoconazole and allopurinol.
Topics: Aged; Allopurinol; Antiprotozoal Agents; Drug Therapy, Combination; Humans; Ketoconazole; Kidney Tra | 1999 |
Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate.
Topics: Acute Disease; Allopurinol; Antiprotozoal Agents; Child, Preschool; Humans; Ketoconazole; Leishmania | 2001 |
No evidence of oxidant events in amphotericin B cytotoxicity versus L. infantum promastigotes.
Topics: Amphotericin B; Animals; Antifungal Agents; Antioxidants; Antiprotozoal Agents; Ascorbic Acid; Catal | 2001 |
Maintenance itraconazole for visceral leishmaniasis in HIV infection.
Topics: Adult; Antifungal Agents; Female; HIV Infections; Humans; Itraconazole; Ketoconazole; Leishmaniasis, | 1992 |
Efficacy of ketoconazole in post-kala-azar dermal leishmaniasis.
Topics: Adult; Humans; Ketoconazole; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male | 1992 |
Ketoconazole in the treatment of antimony- and pentamidine-resistant kala-azar.
Topics: Antimony; Drug Resistance; Humans; Ketoconazole; Leishmaniasis, Visceral; Pentamidine | 1992 |
[Visceral leishmaniasis with partial response to ketoconazole in a patient with positive antibodies to the human immunodeficiency virus].
Topics: Adult; Chronic Disease; HIV Infections; HIV Seropositivity; HIV-1; Humans; Ketoconazole; Leishmanias | 1991 |
Ketoconazole in treatment of visceral leishmaniasis.
Topics: Adolescent; Adult; Drug Administration Schedule; Female; Humans; Ketoconazole; Leishmaniasis, Viscer | 1990 |