Page last updated: 2024-10-29

ketoconazole and Kidney Diseases

ketoconazole has been researched along with Kidney Diseases in 16 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Ketoconazole treatment at a dose of 10 mg/kg daily for 60 days was not as effective as amphotericin B."5.27Treatment of canine blastomycosis with amphotericin B and ketoconazole. ( Edwards, DF; Legendre, AM; Selcer, BA; Stevens, R, 1984)
"Miconazole is a parenterally administered agent for patients acutely ill with candidiasis and other mycotic infections."2.36Antifungal agents used in systemic mycoses. Activity and therapeutic use. ( Craven, PC; Graybill, JR, 1983)
"Cushing's syndrome is known to present with a characteristic set of clinical manifestations and complications, well described in literature."1.51Arterial thrombosis as primary presentation of endogenous Cushing's syndrome. ( Alexander, V; Carey, RA; Dasgupta, R; Koshy, M, 2019)
"Ketoconazole treatment at a dose of 10 mg/kg daily for 60 days was not as effective as amphotericin B."1.27Treatment of canine blastomycosis with amphotericin B and ketoconazole. ( Edwards, DF; Legendre, AM; Selcer, BA; Stevens, R, 1984)
" Gentamicin at toxic doses, however, increased CSA nephrotoxicity."1.27Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy. ( Mihatsch, MJ; Müller, AM; Ryffel, B, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, Q1
Yin, L1
Hartmann, RW1
Alexander, V1
Koshy, M1
Dasgupta, R1
Carey, RA1
Shi, J1
Chapel, S1
Montay, G1
Hardy, P1
Barrett, JS1
Sica, D1
Swan, SK1
Noveck, R1
Leroy, B1
Bhargava, VO1
Brass, C1
Galgiani, JN2
Blaschke, TF1
Defelice, R1
O'Reilly, RA1
Stevens, DA2
Graybill, JR1
Craven, PC1
Legendre, AM1
Selcer, BA1
Edwards, DF1
Stevens, R1
Piketty, C1
George, F1
Weiss, L1
Lavarde, V1
Hernigou, A1
Kazatchkine, MD1
García, R1
Marín, C1
Herrera, J1
Henríquez La Roche, C1
Rubio, L1
Rodríguez-Iturbe, B1
Kramer, MR1
Marshall, SE1
Denning, DW2
Keogh, AM1
Tucker, RM1
Lewiston, NJ1
Theodore, J1
Nováková, I1
Donnelly, P1
de Witte, T1
de Pauw, B1
Boezeman, J1
Veltman, G1
Ackerbauer, H1
Meingassner, JG1
Mieth, H1
Davies, SP1
Webb, WJ1
Patou, G1
Murray, WK1
Ryffel, B1
Müller, AM1
Mihatsch, MJ1
Whiting, PH1
Thomson, AW1
Simpson, JG1
Haddy, RI1
Petry, LJ1
Bond, JA1
Shelton, JA1
Day, CM1
Curry, RW1
Bidgood, WD1

Reviews

2 reviews available for ketoconazole and Kidney Diseases

ArticleYear
Antifungal agents used in systemic mycoses. Activity and therapeutic use.
    Drugs, 1983, Volume: 25, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Central Nervous System; Flucytosine; Humans; Imidazoles; Ketocona

1983
Cyclosporine: toxicity, metabolism, and drug interactions--implications from animal studies.
    Transplantation proceedings, 1985, Volume: 17, Issue:4 Suppl 1

    Topics: Animals; Cyclosporins; Disease Models, Animal; Dogs; Drug Interactions; Gentamicins; Humans; Ketocon

1985

Trials

1 trial available for ketoconazole and Kidney Diseases

ArticleYear
Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Biological Availability; Clarithro

2005

Other Studies

13 other studies available for ketoconazole and Kidney Diseases

ArticleYear
Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Aldosterone; Animals; Benzimidazoles; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Fadrozole;

2014
Arterial thrombosis as primary presentation of endogenous Cushing's syndrome.
    BMJ case reports, 2019, Feb-06, Volume: 12, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Anticoagulants; Aortic Diseases; Celiac Artery; Computed Tomogra

2019
Disposition of ketoconazole, an oral antifungal, in humans.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1

    Topics: Administration, Oral; Adult; Antacids; Antifungal Agents; Child; Drug Interactions; Humans; Imidazol

1982
Treatment of canine blastomycosis with amphotericin B and ketoconazole.
    Journal of the American Veterinary Medical Association, 1984, May-15, Volume: 184, Issue:10

    Topics: Amphotericin B; Animals; Blastomycosis; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Ketoc

1984
Renal aspergilloma in AIDS.
    The American journal of medicine, 1993, Volume: 94, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Aspergillosis; Aspe

1993
Systemic antifungal drugs.
    The Medical letter on drugs and therapeutics, 1997, Sep-12, Volume: 39, Issue:1009

    Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom

1997
[Usefulness of ketoconazole combined with cyclosporin in renal transplantation].
    Investigacion clinica, 1991, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Azathioprine; Biotransformation; Chemical and Drug Induced Liver Injury; Cyclospo

1991
Cyclosporine and itraconazole interaction in heart and lung transplant recipients.
    Annals of internal medicine, 1990, Aug-15, Volume: 113, Issue:4

    Topics: Aspergillosis; Coccidiosis; Cyclosporins; Drug Interactions; Heart Transplantation; Heart-Lung Trans

1990
Itraconazole and cyclosporin nephrotoxicity.
    Lancet (London, England), 1987, Oct-17, Volume: 2, Issue:8564

    Topics: Antifungal Agents; Cyclosporins; Drug Interactions; Drug Therapy, Combination; Humans; Itraconazole;

1987
[Experimental renal infection with Aspergillus fumigatus in mice: a chemotherapeutic model of an organic mycosis].
    Mykosen, 1985, Volume: 28, Issue:5

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Disease Models, An

1985
Renal aspergilloma--a case illustrating the problems of medical therapy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1987, Volume: 2, Issue:6

    Topics: Amphotericin B; Aspergillosis; Female; Flucytosine; Humans; Ketoconazole; Kidney Diseases; Middle Ag

1987
Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy.
    Clinical nephrology, 1986, Volume: 25 Suppl 1

    Topics: Amphotericin B; Animals; Anti-Infective Agents; Cyclosporins; Drug Interactions; Gentamicins; Ketoco

1986
Renal pelvocalyceal abscess secondary to Candida albicans.
    The Journal of family practice, 1986, Volume: 22, Issue:3

    Topics: Abscess; Candidiasis; Female; Humans; Ketoconazole; Kidney Diseases; Kidney Pelvis; Middle Aged

1986