ketoconazole has been researched along with Keratitis in 41 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Keratitis: Inflammation of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis." | 9.24 | Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial. ( Agarwal, T; Maharana, PK; Satpathy, G; Sharma, N; Singhal, D; Sinha, R; Titiyal, JS; Upadhyay, AD; Velpandian, T, 2017) |
| "Oral ketoconazole (100 mg daily for 3 weeks) markedly reduced the severity of experimental Candida albicans keratitis in a group of 10 rabbits." | 7.67 | Oral ketoconazole therapy for experimental candida albicans keratitis in rabbits. ( Ishibashi, Y; Matsumoto, Y, 1984) |
| "Topical ketoconazole (2% ointment three times per day for three weeks) markedly reduced the severity of keratitis produced with Candida albicans inoculation in the right eyes of 20 rabbits." | 7.67 | Topical ketoconazole for experimental Candida keratitis in rabbits. ( Ishibashi, Y; Kaufman, HE, 1986) |
| " The clinical signs of corneal infection disappeared after three (Aspergillus infections) to seven weeks (Fusarium infections) of ketoconazole therapy." | 7.67 | Topical ketoconazole for fungal keratitis. ( Cavazos-Adame, H; Martinez, LA; Mohamed, J; Torres, MA, 1985) |
| "Fungal keratitis is a rare but serious condition that may result in loss of vision." | 5.33 | Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis. ( Ayala-Lugo, R; Barbosa, L; de Kaspar, HM; Sanchez-Di Martino, D; Sonego-Krone, S; Ta, CN; Torres-Alvariza, G, 2006) |
| "To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis." | 5.24 | Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial. ( Agarwal, T; Maharana, PK; Satpathy, G; Sharma, N; Singhal, D; Sinha, R; Titiyal, JS; Upadhyay, AD; Velpandian, T, 2017) |
| ", itraconazole, voriconazole, ketoconazole, econazole and clotrimazole were investigated in order to evaluate their efficacy against filamentous fungi isolated from mycotic keratitis." | 3.81 | In vitro susceptibility of filamentous fungi from mycotic keratitis to azole drugs. ( Babu Singh, YR; Galgóczy, L; Homa, M; Kredics, L; Manikandan, P; Mythili, A; Narendran, V; Panneerselvam, K; Priya, R; Shobana, CS; Vágvölgyi, C, 2015) |
| "Oral ketoconazole (100 mg daily for 3 weeks) markedly reduced the severity of experimental Candida albicans keratitis in a group of 10 rabbits." | 3.67 | Oral ketoconazole therapy for experimental candida albicans keratitis in rabbits. ( Ishibashi, Y; Matsumoto, Y, 1984) |
| "We describe a patient with type I diabetes mellitus and hypothyroidism who developed frank adrenocortical insufficiency while receiving a high-dose ketoconazole therapy for keratitis caused by Acanthamoeba species." | 3.67 | Adrenal crisis in the setting of high-dose ketoconazole therapy. ( Demerjian, Z; Godine, JE; Khosla, S; Wolfson, JS, 1989) |
| "Topical ketoconazole (2% ointment three times per day for three weeks) markedly reduced the severity of keratitis produced with Candida albicans inoculation in the right eyes of 20 rabbits." | 3.67 | Topical ketoconazole for experimental Candida keratitis in rabbits. ( Ishibashi, Y; Kaufman, HE, 1986) |
| " The clinical signs of corneal infection disappeared after three (Aspergillus infections) to seven weeks (Fusarium infections) of ketoconazole therapy." | 3.67 | Topical ketoconazole for fungal keratitis. ( Cavazos-Adame, H; Martinez, LA; Mohamed, J; Torres, MA, 1985) |
| "I treated seven patients with keratomycosis (four with Candida infections and three with Aspergillus infections) with topical and subconjunctival miconazole." | 3.66 | Miconazole therapy for keratomycosis. ( Foster, CS, 1981) |
| "Two patients, a 48-year-old woman and a 44-year-old man, with fungal keratitis were treated with orally administered ketoconazole, a new antifungal agent." | 3.66 | Oral ketoconazole therapy for keratomycosis. ( Ishibashi, Y, 1983) |
| "Acanthamoeba spp." | 2.41 | [Keratitis caused by Acanthamoeba spp.: presentation of 10 cases]. ( Barrón, J; de Fernando, S; Gaztelurrutia, L; López, L; Pérez-Irezábal, J; Vilar, B, 2000) |
| "Keratitis is a major cause of avoidable visual impairment." | 1.46 | Condition responsive nanoparticles for managing infection and inflammation in keratitis. ( Ahsan, SM; Rao, CM, 2017) |
| "Fungal keratitis is a rare but serious condition that may result in loss of vision." | 1.33 | Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis. ( Ayala-Lugo, R; Barbosa, L; de Kaspar, HM; Sanchez-Di Martino, D; Sonego-Krone, S; Ta, CN; Torres-Alvariza, G, 2006) |
| "Ketoconazole also has a therapeutic effect in the reduction of well established A." | 1.26 | Ketoconazole: a new imidazole antifungal agent has both prophylactic potential and therapeutic efficacy in keratomycosis of rabbits. ( Oji, EO, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (48.78) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahsan, SM | 1 |
| Rao, CM | 1 |
| Sharma, N | 2 |
| Singhal, D | 2 |
| Maharana, PK | 2 |
| Sinha, R | 2 |
| Agarwal, T | 2 |
| Upadhyay, AD | 1 |
| Velpandian, T | 2 |
| Satpathy, G | 2 |
| Titiyal, JS | 2 |
| Sahay, P | 1 |
| Saluja, G | 1 |
| Bandivadekar, P | 1 |
| Chako, J | 1 |
| Shobana, CS | 1 |
| Mythili, A | 1 |
| Homa, M | 1 |
| Galgóczy, L | 1 |
| Priya, R | 1 |
| Babu Singh, YR | 1 |
| Panneerselvam, K | 1 |
| Vágvölgyi, C | 2 |
| Kredics, L | 2 |
| Narendran, V | 1 |
| Manikandan, P | 1 |
| Varga, J | 1 |
| Kocsubé, S | 1 |
| Rajaraman, R | 1 |
| Raghavan, A | 1 |
| Dóczi, I | 1 |
| Bhaskar, M | 1 |
| Németh, TM | 1 |
| Antal, Z | 1 |
| Venkatapathy, N | 1 |
| Samson, RA | 1 |
| Chockaiya, M | 1 |
| Palanisamy, M | 1 |
| Verkley, GJ | 1 |
| Gené, J | 2 |
| Guarro, J | 2 |
| Pérez-Santonja, JJ | 1 |
| Rodríguez, AE | 1 |
| Colom, MF | 1 |
| Alio, JL | 1 |
| Ferrer, C | 1 |
| Trichet, E | 1 |
| Cohen-Bacrie, S | 1 |
| Conrath, J | 1 |
| Drancourt, M | 1 |
| Hoffart, L | 1 |
| Höfling-Lima, AL | 1 |
| De Freitas, D | 1 |
| Godoy, P | 1 |
| Zorat-Yu, ML | 1 |
| Zaror, L | 1 |
| Fischman, O | 1 |
| Sonego-Krone, S | 1 |
| Sanchez-Di Martino, D | 1 |
| Ayala-Lugo, R | 1 |
| Torres-Alvariza, G | 1 |
| Ta, CN | 1 |
| Barbosa, L | 1 |
| de Kaspar, HM | 1 |
| Weinstein, WL | 1 |
| Moore, PA | 1 |
| Sanchez, S | 1 |
| Dietrich, UM | 1 |
| Wooley, RE | 1 |
| Ritchie, BW | 1 |
| Therese, KL | 1 |
| Bagyalakshmi, R | 1 |
| Madhavan, HN | 1 |
| Deepa, P | 1 |
| Kanavi, MR | 1 |
| Foroutan, AR | 1 |
| Kamel, MR | 1 |
| Afsar, N | 1 |
| Javadi, MA | 1 |
| Hirst, LW | 1 |
| Green, WR | 1 |
| Merz, W | 1 |
| Kaufmann, C | 1 |
| Visvesvara, GS | 1 |
| Jensen, A | 1 |
| Howard, M | 1 |
| Ishibashi, Y | 7 |
| Matsumoto, Y | 3 |
| Foster, CS | 1 |
| Oji, EO | 1 |
| O'Day, DM | 3 |
| Ray, WA | 2 |
| Robinson, R | 2 |
| Head, WS | 3 |
| Lund, OE | 1 |
| Miño de Kaspar, H | 1 |
| Klauss, V | 1 |
| Perlman, EM | 1 |
| Binns, L | 1 |
| López, L | 1 |
| de Fernando, S | 1 |
| Gaztelurrutia, L | 1 |
| Vilar, B | 1 |
| Pérez-Irezábal, J | 1 |
| Barrón, J | 1 |
| Robinson, RD | 1 |
| Williams, TE | 1 |
| Gedde, S | 1 |
| Bloom, PA | 1 |
| Laidlaw, DA | 1 |
| Easty, DL | 2 |
| Warnock, DW | 1 |
| Maskin, SL | 1 |
| Alfonso, E | 1 |
| Hazen, PG | 2 |
| Walker, AE | 1 |
| Stewart, JJ | 1 |
| Carney, JF | 1 |
| Engstrom, CW | 1 |
| Turgeon, KL | 1 |
| Coriglione, G | 1 |
| Stella, G | 1 |
| Gafa, L | 1 |
| Spata, G | 1 |
| Oliveri, S | 1 |
| Padhye, AA | 1 |
| Ajello, L | 1 |
| Ragge, NK | 1 |
| Hart, JC | 1 |
| Tyers, AG | 1 |
| Khosla, S | 1 |
| Wolfson, JS | 1 |
| Demerjian, Z | 1 |
| Godine, JE | 1 |
| Carney, P | 1 |
| Lynch, WS | 1 |
| Thomas, PA | 2 |
| Abraham, DJ | 2 |
| Kalavathy, CM | 2 |
| Rajasekaran, J | 2 |
| Watanabe, R | 1 |
| Hommura, S | 1 |
| Yasuraoka, K | 1 |
| Ishii, K | 1 |
| Koyama, T | 1 |
| Endo, T | 1 |
| Yagita, K | 1 |
| Joseph, PC | 1 |
| Gracner, B | 1 |
| Fitzsimons, R | 1 |
| Peters, AL | 1 |
| Kaufman, HE | 1 |
| Komadina, TG | 1 |
| Wilkes, TD | 1 |
| Shock, JP | 1 |
| Ulmer, WC | 1 |
| Jackson, J | 1 |
| Bradsher, RW | 1 |
| Torres, MA | 1 |
| Mohamed, J | 1 |
| Cavazos-Adame, H | 1 |
| Martinez, LA | 1 |
1 review available for ketoconazole and Keratitis
| Article | Year |
|---|---|
[Keratitis caused by Acanthamoeba spp.: presentation of 10 cases].
Topics: Acanthamoeba; Adolescent; Adrenal Cortex Hormones; Adult; Amebiasis; Amebicides; Animals; Biguanides | 2000 |
1 trial available for ketoconazole and Keratitis
| Article | Year |
|---|---|
Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Antifungal Agents; Chemotherapy, Adjuvan | 2017 |
39 other studies available for ketoconazole and Keratitis
| Article | Year |
|---|---|
Condition responsive nanoparticles for managing infection and inflammation in keratitis.
Topics: Animals; Antibodies; Antifungal Agents; Cells, Cultured; Cornea; Drug Delivery Systems; Eye Infectio | 2017 |
Management Algorithm for Fungal Keratitis: The TST (Topical, Systemic, and Targeted Therapy) Protocol.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Antifungal Agents; Chi | 2019 |
In vitro susceptibility of filamentous fungi from mycotic keratitis to azole drugs.
Topics: Antifungal Agents; Azoles; Corneal Ulcer; Drug Resistance, Fungal; Eye Infections, Fungal; Fungi; Hu | 2015 |
Infectious keratitis caused by Aspergillus tubingensis.
Topics: Administration, Oral; Aged; Antifungal Agents; Aspergillosis; Aspergillus; Corneal Transplantation; | 2009 |
Pyrenochaeta keratinophila sp. nov., isolated from an ocular infection in Spain.
Topics: Aged; Antifungal Agents; Combined Modality Therapy; Diabetes Complications; Female; Humans; Keratiti | 2010 |
Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia.
Topics: Administration, Oral; Administration, Topical; Amikacin; Anti-Bacterial Agents; Antifungal Agents; C | 2011 |
Corneal ulcer caused by the new fungal species Sarcopodium oculorum.
Topics: Antifungal Agents; Child; Corneal Ulcer; Eye Infections, Fungal; Humans; Keratitis; Ketoconazole; Ma | 2002 |
Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Child; Drug The | 2006 |
In vitro efficacy of a buffered chelating solution as an antimicrobial potentiator for antifungal drugs against fungal pathogens obtained from horses with mycotic keratitis.
Topics: Animals; Antifungal Agents; Chelating Agents; Drug Synergism; Horse Diseases; Horses; Itraconazole; | 2006 |
In-vitro susceptibility testing by agar dilution method to determine the minimum inhibitory concentrations of amphotericin B, fluconazole and ketoconazole against ocular fungal isolates.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Candida; Drug Resistance, Fungal; Eye Diseases; Fluc | 2006 |
Candida interface keratitis after deep anterior lamellar keratoplasty: clinical, microbiologic, histopathologic, and confocal microscopic reports.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis; Cornea; C | 2007 |
Management of Acanthamoeba keratitis. A case report and review of the literature.
Topics: Adult; Aged; Amebiasis; Combined Modality Therapy; Cornea; Corneal Transplantation; Female; Humans; | 1984 |
Oral ketoconazole therapy for experimental candida albicans keratitis in rabbits.
Topics: Administration, Oral; Animals; Candidiasis; Cornea; Female; Keratitis; Ketoconazole; Male; Rabbits; | 1984 |
Miconazole therapy for keratomycosis.
Topics: Adult; Aged; Aspergillosis; Candidiasis; Corneal Diseases; Female; Humans; Imidazoles; Keratitis; Ke | 1981 |
Ketoconazole: a new imidazole antifungal agent has both prophylactic potential and therapeutic efficacy in keratomycosis of rabbits.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus flavus; Imidazoles; Keratitis; Ketoconazole; | 1982 |
Oral ketoconazole therapy for keratomycosis.
Topics: Administration, Oral; Adult; Corneal Ulcer; Female; Humans; Imidazoles; Keratitis; Ketoconazole; Mal | 1983 |
[Effects of oral ketoconazole in experimental fungal keratitis].
Topics: Administration, Oral; Animals; Candidiasis; Keratitis; Ketoconazole; Rabbits | 1983 |
Efficacy of antifungal agents in the cornea. II. Influence of corticosteroids.
Topics: Adrenal Cortex Hormones; Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; | 1984 |
[Strategy for examination and therapy of mycotic keratitis].
Topics: Acremonium; Administration, Oral; Adolescent; Amphotericin B; Antifungal Agents; Contact Lenses; Dru | 1993 |
Intense photophobia caused by Arthrographis kalrae in a contact lens-wearing patient.
Topics: Administration, Oral; Amphotericin B; Antifungal Agents; Contact Lenses; Cornea; Eye Infections, Fun | 1997 |
The evaluation of therapeutic responses in experimental keratomycosis.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count | 1992 |
Treatment failure in a case of fungal keratitis caused by Pseudallescheria boydii.
Topics: Antifungal Agents; Eye Infections, Fungal; Humans; Itraconazole; Keratitis; Keratoplasty, Penetratin | 1992 |
Fungal keratitis after radial keratotomy.
Topics: Adult; Amphotericin B; Candidiasis; Eye Infections, Fungal; Female; Humans; Keratitis; Keratotomy, R | 1992 |
Keratitis, ichthyosis, and deafness (KID) syndrome: management with chronic oral ketoconazole therapy.
Topics: Administration, Oral; Adult; Candidiasis, Cutaneous; Carcinoma, Squamous Cell; Female; Foot Diseases | 1992 |
Neosartorya fischeri var fischeri (Wehmer) Malloch and Cain 1972 (anamorph: Aspergillus fischerianus Samson and Gams 1985) as a cause of mycotic keratitis.
Topics: Aspergillosis; Aspergillus; Cornea; Eye Enucleation; Eye Infections, Fungal; Humans; Keratitis; Keto | 1990 |
A case of fungal keratitis caused by Scopulariopsis brevicaulis: treatment with antifungal agents and penetrating keratoplasty.
Topics: Adult; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Eye Infections, Fungal; Humans; | 1990 |
Adrenal crisis in the setting of high-dose ketoconazole therapy.
Topics: Acanthamoeba; Acute Disease; Adrenal Cortex Diseases; Amebiasis; Animals; Diabetes Mellitus, Type 1; | 1989 |
Keratitis, ichthyosis, and deafness syndrome with development of multiple cutaneous neoplasms.
Topics: Adult; Carcinoma, Squamous Cell; Deafness; Female; Humans; Ichthyosis; Keratitis; Ketoconazole; Neop | 1989 |
Oral itraconazole therapy for mycotic keratitis.
Topics: Adolescent; Adult; Antifungal Agents; Aspergillosis; Child; Female; Fusarium; Humans; Itraconazole; | 1988 |
[Case of Acanthamoeba keratitis].
Topics: Acanthamoeba; Adult; Amebiasis; Animals; Antifungal Agents; Drug Therapy, Combination; Humans; Itrac | 1988 |
Itraconazole therapy for fungal keratitis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Routes; Female; Humans; Itraco | 1987 |
[Therapeutic possibilities in mycotic corneal processes].
Topics: Adult; Aged; Drug Therapy, Combination; Humans; Keratitis; Ketoconazole; Male; Middle Aged; Mycoses; | 1987 |
Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis.
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Humans; Keratitis; Ketoconazole; Male; Miconazole | 1986 |
Topical ketoconazole for experimental Candida keratitis in rabbits.
Topics: Administration, Topical; Animals; Candidiasis; Keratitis; Ketoconazole; Ointments; Rabbits | 1986 |
Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis.
Topics: Animals; Humans; Keratitis; Ketoconazole; Miconazole; Mycoses; Rabbits | 1986 |
Treatment of Aspergillus fumigatus keratitis in rabbits with oral and topical ketoconazole.
Topics: Administration, Oral; Administration, Topical; Animals; Aspergillosis; Drug Evaluation, Preclinical; | 1985 |
Treatment of Aspergillus fumigatus keratitis in rabbits with oral and topical ketoconazole.
Topics: Administration, Oral; Administration, Topical; Animals; Aspergillosis; Aspergillus fumigatus; Kerati | 1985 |
Statistical analysis for experimental models of ocular disease: continuous response measures.
Topics: Amphotericin B; Analysis of Variance; Animals; Candidiasis; Eye Diseases; In Vitro Techniques; Kerat | 1985 |
Topical ketoconazole for fungal keratitis.
Topics: Administration, Topical; Adult; Aspergillosis; Female; Fusarium; Humans; Keratitis; Ketoconazole; Ma | 1985 |