ketoconazole has been researched along with Interstitial Cell Tumor in 3 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole treatment decreased circulating testosterone in childhood, supported by experimental suppression of testosterone production in his adult testis tissue cultured ex vivo." | 1.46 | Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis. ( Blomberg Jensen, M; Christiansen, P; Frederiksen, H; Grønkær Toft, B; Juel Mortensen, L; Juul, A; Jørgensen, A; Loya, AC; Nielsen, JE; Rajpert-De Meyts, E; Rønholt, AM; Skakkebæk, NE, 2017) |
| "Lansoprazole is a substituted benzimidazole which inhibits gastric acid secretion by inhibiting the hydrogen-potassium ATPase (proton pump) in the parietal cell." | 1.29 | Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole. ( Ando, T; Fort, FL; Hamashima, T; Hodgen, GD; Kitazaki, T; Mahony, MC; Miyajima, H; Sato, S; Suzuki, T; Yamamoto, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Juel Mortensen, L | 1 |
| Blomberg Jensen, M | 1 |
| Christiansen, P | 1 |
| Rønholt, AM | 1 |
| Jørgensen, A | 1 |
| Frederiksen, H | 1 |
| Nielsen, JE | 1 |
| Loya, AC | 1 |
| Grønkær Toft, B | 1 |
| Skakkebæk, NE | 1 |
| Rajpert-De Meyts, E | 1 |
| Juul, A | 1 |
| Fort, FL | 1 |
| Miyajima, H | 1 |
| Ando, T | 1 |
| Suzuki, T | 1 |
| Yamamoto, M | 1 |
| Hamashima, T | 1 |
| Sato, S | 1 |
| Kitazaki, T | 1 |
| Mahony, MC | 1 |
| Hodgen, GD | 1 |
| Chaudhary, LR | 1 |
| Stocco, DM | 1 |
3 other studies available for ketoconazole and Interstitial Cell Tumor
| Article | Year |
|---|---|
Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis.
Topics: Adult; Body Composition; Body Height; Bone and Bones; Fertility; Gonadotropins; Hormone Antagonists; | 2017 |
Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Carcinogens; Chorionic Gonadotropin; Dose-Response | 1995 |
Inhibition of hCG- and cAMP-stimulated progesterone production in MA-10 mouse Leydig tumor cells by ketoconazole.
Topics: Animals; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Hydroxycholesterols; Ketoconazo | 1989 |