ketoconazole has been researched along with Infective Endocarditis in 8 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 7.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " Review of these five cases and 31 additional relapsing cases from the literature indicates that fungal endocarditis or endarteritis without surgical treatment, underlying lymphoreticular neoplasm, and amphotericin B dosage of less than 2 g appear to be associated with relapse of PDH." | 5.26 | Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis. ( Alford, RH; Bradsher, RW; Hawkins, SS; Spickard, WA, 1982) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 5.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 3.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " The proper duration and dosage and the combination of antifungal drugs have not been clearly defined." | 2.38 | [Primary Aspergillus endocarditis. Apropos of a case and review of the international literature]. ( Cajot, MA; Gosselin, B; Goullard, L; Koussa, A; Marquette, F; Pol, A; Roux, JP; Soots, G; Warembourg, H, 1992) |
| " Review of these five cases and 31 additional relapsing cases from the literature indicates that fungal endocarditis or endarteritis without surgical treatment, underlying lymphoreticular neoplasm, and amphotericin B dosage of less than 2 g appear to be associated with relapse of PDH." | 1.26 | Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis. ( Alford, RH; Bradsher, RW; Hawkins, SS; Spickard, WA, 1982) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 1.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samelson, LE | 1 |
| Lerner, SA | 1 |
| Resnekov, L | 1 |
| Anagnostopoulos, C | 1 |
| Bradsher, RW | 1 |
| Alford, RH | 1 |
| Hawkins, SS | 1 |
| Spickard, WA | 1 |
| Drouhet, E | 1 |
| Guilmet, D | 1 |
| Kouvalchouk, JF | 1 |
| Chapman, A | 1 |
| Ziza, JM | 1 |
| Laudet, J | 1 |
| Brodaty, D | 1 |
| Thomas, D | 1 |
| Mogahed, A | 1 |
| Leclerc, JP | 1 |
| Grosgogeat, Y | 1 |
| Roux, JP | 1 |
| Koussa, A | 1 |
| Cajot, MA | 1 |
| Marquette, F | 1 |
| Goullard, L | 1 |
| Gosselin, B | 1 |
| Pol, A | 1 |
| Warembourg, H | 1 |
| Soots, G | 1 |
| Longman, LP | 1 |
| Martin, MV | 1 |
| Pruett, TL | 1 |
| Rotstein, OD | 1 |
| Anderson, RW | 1 |
| Simmons, RL | 1 |
| Vartian, CV | 1 |
| Shlaes, DM | 1 |
| Padhye, AA | 1 |
| Ajello, L | 1 |
1 review available for ketoconazole and Infective Endocarditis
| Article | Year |
|---|---|
[Primary Aspergillus endocarditis. Apropos of a case and review of the international literature].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Combined Modality Therapy; | 1992 |
7 other studies available for ketoconazole and Infective Endocarditis
| Article | Year |
|---|---|
Relapse of Candida parapsilosis endocarditis after long-term suppression with flucytosin: retreatment with valve replacement and ketoconazole.
Topics: Adult; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Endocarditis; Female; Flucy | 1980 |
Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis.
Topics: Aged; Amphotericin B; Antifungal Agents; Endocarditis; Histoplasmosis; Humans; Imidazoles; Ketoconaz | 1982 |
[First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B].
Topics: Adult; Amphotericin B; Antifungal Agents; Endocarditis; Female; Heart Valve Prosthesis; Humans; Imid | 1982 |
Prosthetic valve endocarditis caused by Trichosporon cutaneum.
Topics: Aortic Valve; Basidiomycota; Endocarditis; Female; Heart Valve Prosthesis; Humans; Ketoconazole; Mid | 1984 |
A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Endocarditis; Fluc | 1987 |
Tricuspid valve Candida endocarditis. Successful treatment with valve-sparing debridement and antifungal chemotherapy in a multiorgan transplant recipient.
Topics: Adult; Amphotericin B; Antifungal Agents; Candidiasis; Combined Modality Therapy; Debridement; Endoc | 1986 |
Wangiella dermatitidis endocarditis in an intravenous drug user.
Topics: Adult; Amphotericin B; Aortic Valve; Drug Therapy, Combination; Endocarditis; Heart Valve Diseases; | 1985 |