ketoconazole has been researched along with Infections, Plasmodium in 7 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To predict the optimal chemoprophylactic dose of mefloquine in infants of 5-10 kg using physiologically based pharmacokinetic (PBPK) and clinical effectiveness models." | 5.51 | Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children. ( Cleary, Y; Johnson, TN; Parrott, N; Reigner, B; Smith, JR; Toovey, S, 2019) |
| "To predict the optimal chemoprophylactic dose of mefloquine in infants of 5-10 kg using physiologically based pharmacokinetic (PBPK) and clinical effectiveness models." | 1.51 | Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children. ( Cleary, Y; Johnson, TN; Parrott, N; Reigner, B; Smith, JR; Toovey, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cross, RM | 1 |
| Flanigan, DL | 1 |
| Monastyrskyi, A | 1 |
| LaCrue, AN | 1 |
| Sáenz, FE | 1 |
| Maignan, JR | 1 |
| Mutka, TS | 1 |
| White, KL | 1 |
| Shackleford, DM | 2 |
| Bathurst, I | 1 |
| Fronczek, FR | 1 |
| Wojtas, L | 1 |
| Guida, WC | 1 |
| Charman, SA | 2 |
| Burrows, JN | 1 |
| Kyle, DE | 1 |
| Manetsch, R | 1 |
| O' Neill, PM | 1 |
| Stocks, PA | 1 |
| Sabbani, S | 1 |
| Roberts, NL | 1 |
| Amewu, RK | 1 |
| Shore, ER | 1 |
| Aljayyoussi, G | 1 |
| Angulo-Barturén, I | 1 |
| Belén, M | 1 |
| Bazaga, SF | 1 |
| Martínez, MS | 1 |
| Campo, B | 1 |
| Sharma, R | 1 |
| Ryan, E | 1 |
| Chen, G | 1 |
| Davies, J | 1 |
| Nixon, GL | 1 |
| Biagini, GA | 1 |
| Ward, SA | 1 |
| Johnson, TN | 1 |
| Cleary, Y | 1 |
| Parrott, N | 1 |
| Reigner, B | 1 |
| Smith, JR | 1 |
| Toovey, S | 1 |
| Chandra, R | 1 |
| Puri, SK | 1 |
| Tripathi, R | 2 |
| Rizvi, A | 1 |
| Pandey, SK | 1 |
| Dwivedi, H | 1 |
| Saxena, JK | 1 |
| Awasthi, A | 1 |
| Dutta, GP | 1 |
| Raether, W | 1 |
| Seidenath, H | 1 |
7 other studies available for ketoconazole and Infections, Plasmodium
| Article | Year |
|---|---|
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Paras | 2014 |
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.
Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Drug Stability; Humans; Inhibi | 2018 |
Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children.
Topics: Adult; Age Factors; Antimalarials; Child; Child, Preschool; Drug Dosage Calculations; Drug Interacti | 2019 |
Arteether resistance reversal by ketoconazole/fluconazole in rodent malaria parasite Plasmodium vinckei.
Topics: Animals; Antifungal Agents; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; | 2015 |
Ketoconazole, a cytochrome P(450) inhibitor can potentiate the antimalarial action of α/β arteether against MDR Plasmodium yoelii nigeriensis.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Synergism; Drug T | 2013 |
Mefloquine resistance reversal action of ketoconazole - a cytochrome P450 inhibitor, against mefloquine-resistant malaria.
Topics: Animals; Antimalarials; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug R | 2005 |
Ketoconazole and other potent antimycotic azoles exhibit pronounced activity against Trypanosoma cruzi, Plasmodium berghei and Entamoeba histolytica in vivo.
Topics: Amebiasis; Animals; Antifungal Agents; Chagas Disease; Entamoeba histolytica; Entamoebiasis; Ketocon | 1984 |