Page last updated: 2024-10-29

ketoconazole and Hypokalemia

ketoconazole has been researched along with Hypokalemia in 11 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The first-line treatment for Cushing's disease is transsphenoidal surgery, after which the rates of remission are 60 to 80%, with long-term recurrence of 20 to 30%, even in those with real initial remission."1.72Evaluation of ketoconazole as a treatment for Cushing's disease in a retrospective cohort. ( Costa, MCB; Czepielewski, MA; de Melo, RB; Mattos, ACV; Rodrigues, TDC; Viecceli, C, 2022)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Pivonello, R1
Simeoli, C1
Di Paola, N1
Colao, A1
Viecceli, C1
Mattos, ACV1
Costa, MCB1
de Melo, RB1
Rodrigues, TDC1
Czepielewski, MA1
Seow, CJ1
Young, WF1
George, JC1
Vedamurthy, D1
Bermudez, M1
Kennedy, JW1
Izzedine, H1
Besse, B1
Lazareth, A1
Bourry, EF1
Soria, JC1
Brito, JP1
Singh, E1
Basu, A1
Barna, M1
Wilson, K1
Chiaruttini, R1
Muchowski, K1
Carmona-Bayonas, A1
Soler, IO1
Gómez, FI1
Billalabeitia, EG1
Saura, HP1
Tafalla, MS1
Díaz, MP1
Donovan, JT1
Otis, CN1
Powell, JL1
Cathcart, HK1
Nelson, MR1
Smith, D1
Erskine, D1
Gazzard, BG1
Rickman, T1
Garmany, R1
Doherty, T1
Benson, D1
Okusa, MD1

Reviews

1 review available for ketoconazole and Hypokalemia

ArticleYear
Cushing's disease: adrenal steroidogenesis inhibitors.
    Pituitary, 2022, Volume: 25, Issue:5

    Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Female; Humans; Hypokalemia; Ketoconazole; Male; Mety

2022

Other Studies

10 other studies available for ketoconazole and Hypokalemia

ArticleYear
Evaluation of ketoconazole as a treatment for Cushing's disease in a retrospective cohort.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Cabergoline; Cushing Syndrome; Humans; Hydrocortisone; Hypokalemia; Ketoconazole; Pituitary ACTH Hyp

2022
An Overlooked Cause of Hypokalemia.
    The American journal of medicine, 2017, Volume: 130, Issue:10

    Topics: 14-alpha Demethylase Inhibitors; Adenoma; Cabergoline; Cushing Syndrome; Dopamine Agonists; Ergoline

2017
Quiz Page October 2016: Severe Hypokalemia, Metabolic Alkalosis, and Malignancy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 68, Issue:4

    Topics: ACTH Syndrome, Ectopic; Alkalosis; Amiloride; Cytochrome P-450 CYP3A Inhibitors; Diabetes Insipidus;

2016
Hypokalemia, metabolic alkalosis, and hypertension in a lung cancer patient.
    Kidney international, 2009, Volume: 76, Issue:1

    Topics: Aged; Alkalosis; Cushing Syndrome; France; Humans; Hypertension; Hypokalemia; Ketoconazole; Lung Neo

2009
Iatrogenic heart block during treatment of a patient with Cushing's syndrome: report of a case.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Aged, 80 and over; Alkalosis; Antihypertensive Agents; Cushing Syndrome; Cytochrome P-450 CYP3A; Cyt

2012
Diagnostic puzzler: hypertension in teen.
    The Journal of family practice, 2012, Volume: 61, Issue:9

    Topics: Adenoma; Adolescent; Adrenal Glands; Antifungal Agents; Cushing Syndrome; Diagnosis, Differential; D

2012
Tailored hormonal therapy in secretory adrenocortical cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang

2007
Cushing's syndrome secondary to malignant lipoid cell tumor of the ovary.
    Gynecologic oncology, 1993, Volume: 50, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cushing Syndrome; Female; Humans; H

1993
Ventricular fibrillation secondary to itraconazole induced hypokalaemia.
    The Journal of infection, 1993, Volume: 26, Issue:3

    Topics: Adult; Antifungal Agents; Humans; Hypokalemia; Itraconazole; Ketoconazole; Male; Ventricular Fibrill

1993
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:4

    Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Adrenocorticotropic Hormone; Aged; Alkalosis; Comorbidity; C

2001