ketoconazole has been researched along with Hyperparathyroidism, Secondary in 2 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Hyperparathyroidism, Secondary: Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The calcimimetic cinacalcet hydrochloride (cinacalcet) is used for treatment of patients with chronic kidney disease with secondary hyperparathyroidism, a population that commonly receives multiple concurrent medications." | 5.12 | Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole. ( Harris, RZ; Padhi, D; Salfi, M; Sullivan, JT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harris, RZ | 1 |
| Salfi, M | 1 |
| Sullivan, JT | 1 |
| Padhi, D | 1 |
| Kawahara, M | 1 |
| Iwasaki, Y | 1 |
| Sakaguchi, K | 1 |
| Taguchi, T | 1 |
| Nishiyama, M | 1 |
| Nigawara, T | 1 |
| Tsugita, M | 1 |
| Kambayashi, M | 1 |
| Suda, T | 1 |
| Hashimoto, K | 1 |
1 trial available for ketoconazole and Hyperparathyroidism, Secondary
| Article | Year |
|---|---|
Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole.
Topics: Administration, Oral; Adult; Analysis of Variance; Antifungal Agents; Area Under Curve; Calcium; Cin | 2007 |
1 other study available for ketoconazole and Hyperparathyroidism, Secondary
| Article | Year |
|---|---|
Predominant role of 25OHD in the negative regulation of PTH expression: clinical relevance for hypovitaminosis D.
Topics: Animals; Base Sequence; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Feedback, Physiological; G | 2008 |