ketoconazole has been researched along with Hypercholesterolemia in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole has been shown to be teratogenic at high, toxic doses in pregnant rats." | 2.38 | Safety aspects of oral antifungal agents. ( Coussement, W; De Coster, R; Lampo, A; Marsboom, R; Van Cauteren, H; Vandenberghe, J; Vanparys, P, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stein, CA | 1 |
| Goel, S | 1 |
| Ghavamian, R | 1 |
| Gylling, H | 1 |
| Vanhanen, H | 1 |
| Miettinen, TA | 1 |
| Van Cauteren, H | 1 |
| Lampo, A | 1 |
| Vandenberghe, J | 1 |
| Vanparys, P | 1 |
| Coussement, W | 1 |
| De Coster, R | 1 |
| Marsboom, R | 1 |
| Leal-Cerro, A | 1 |
| García-Luna, PP | 1 |
| Pereira, JL | 1 |
| Serrera, JL | 1 |
| Pumar, A | 1 |
| Astorga, R | 1 |
1 review available for ketoconazole and Hypercholesterolemia
| Article | Year |
|---|---|
Safety aspects of oral antifungal agents.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Antifungal Agents; Endocrine Glands; Hum | 1990 |
1 trial available for ketoconazole and Hypercholesterolemia
| Article | Year |
|---|---|
Atorvastatin--a new lipid-lowering drug.
Topics: Anti-Bacterial Agents; Anticholesteremic Agents; Antifungal Agents; Atorvastatin; Dose-Response Rela | 1997 |
3 other studies available for ketoconazole and Hypercholesterolemia
| Article | Year |
|---|---|
Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy.
Topics: Aged, 80 and over; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; | 2007 |
Effects of ketoconazole on cholesterol precursors and low density lipoprotein kinetics in hypercholesterolemia.
Topics: Apolipoproteins B; Cholesterol; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; | 1993 |
Ketoconazole: a new type of agent in the treatment of hypercholesterolemia?
Topics: Cholesterol; Humans; Hypercholesterolemia; Ketoconazole; Triglycerides | 1990 |