ketoconazole has been researched along with Hirsutism in 22 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole was administered in a case of hirsutismus over a period of 4 months with high doses of 800 mg/day, and bilateral papilledema developed." | 7.68 | Ketoconazole induced papilledema. ( Akbatur, H; Bilgihan, K; Cakir, N; Hasanerisoğlu, B; Or, M, 1993) |
| "The effects of ketoconazole, a synthetic imidazole derivate, were evaluated in 42 women affected by acne (17 cases) and/or hirsutism (36 cases) treated with 400 mg/day for 3-6 months." | 7.68 | Ketoconazole therapy for women with acne and/or hirsutism. ( Capelli, M; Dal Prato, L; Fabbri, R; Flamigni, C; Magrini, O; Mantovani, B; Venturoli, S, 1990) |
| "Twelve women affected by functional postpuberal hirsutism were administered daily with 400 mg of ketoconazole." | 7.67 | Clinical and hormonal effects of ketoconazole on hirsutism in women. ( De Pedrini, P; Montemurro, G; Spanò, G; Tommaselli, A, 1988) |
| "Hirsutism was evaluated by the Ferriman-Gallwey score, and hair diameter and hair growth rate were determined by a special image analysis processor in basal conditions and after 90, 180, 270, and 360 days of treatment." | 6.69 | A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. ( Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S, 1999) |
| "To determine the efficacy of ketoconazole in the treatment of hirsutism, clinical and hormonal effects of this agent were evaluated with a randomized, placebo-controlled, double-blind cross-over study design." | 5.07 | Effects of ketoconazole in hirsute women. ( Akalin, S, 1991) |
| "Ketoconazole was administered in a case of hirsutismus over a period of 4 months with high doses of 800 mg/day, and bilateral papilledema developed." | 3.68 | Ketoconazole induced papilledema. ( Akbatur, H; Bilgihan, K; Cakir, N; Hasanerisoğlu, B; Or, M, 1993) |
| "The effects of ketoconazole, a synthetic imidazole derivate, were evaluated in 42 women affected by acne (17 cases) and/or hirsutism (36 cases) treated with 400 mg/day for 3-6 months." | 3.68 | Ketoconazole therapy for women with acne and/or hirsutism. ( Capelli, M; Dal Prato, L; Fabbri, R; Flamigni, C; Magrini, O; Mantovani, B; Venturoli, S, 1990) |
| "Hirsutism was evaluated by the Ferriman-Gallwey score, and hair diameter and hair growth rate were determined by a special image analysis processor in basal conditions and after 90, 180, 270, and 360 days of treatment." | 2.69 | A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. ( Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S, 1999) |
| "Polycystic ovary syndrome is the most common endocrinological problem associated with hirsutism." | 2.68 | Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome. ( Gökmen, O; Gülekli, B; Işik, AZ; Senöz, S, 1996) |
| "BLA = bilateral adrenalectomy CD = Cushing disease CS = Cushing syndrome eCRF = electronic case report form MRI = magnetic resonance imaging PCOS = polycystic ovary syndrome." | 1.46 | BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. ( Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS, 2017) |
| "Ketoconazole is an orally active antimycotic agent and a potent inhibitor of gonadal and adrenal steroidogenesis." | 1.28 | Low-dose ketoconazole treatment in hirsute women. ( Biason, A; Boscaro, M; Mantero, F; Scaroni, C; Sonino, N, 1990) |
| "Ketoconazole treatment decreased testosterone, androstenedione and dehydroepiandrosterone sulfate, while 17-alfahydroxyprogesterone increased." | 1.28 | Evaluation of clinical and hormonal effects in hirsute women treated with ketoconazole. ( Conget, JI; Ferrer, J; González-Clemente, JM; Halperin, I; Martinez-Osaba, MJ; Vilardell, E, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geer, EB | 1 |
| Shafiq, I | 1 |
| Gordon, MB | 1 |
| Bonert, V | 1 |
| Ayala, A | 1 |
| Swerdloff, RS | 1 |
| Katznelson, L | 1 |
| Lalazar, Y | 1 |
| Manuylova, E | 1 |
| Pulaski-Liebert, KJ | 1 |
| Carmichael, JD | 1 |
| Hannoush, Z | 1 |
| Surampudi, V | 1 |
| Broder, MS | 1 |
| Cherepanov, D | 1 |
| Eagan, M | 1 |
| Lee, J | 1 |
| Said, Q | 1 |
| Neary, MP | 1 |
| Biller, BMK | 1 |
| Piraccini, BM | 1 |
| Alessandrini, A | 1 |
| Carpenter, PC | 1 |
| Turk, DM | 1 |
| Vidal-Puig, AJ | 1 |
| Muñoz-Torres, M | 1 |
| Jódar-Gimeno, E | 1 |
| García-Calvente, CJ | 1 |
| Lardelli, P | 1 |
| Ruiz-Requena, ME | 1 |
| Escobar-Jiménez, F | 1 |
| Or, M | 1 |
| Akbatur, H | 1 |
| Hasanerisoğlu, B | 1 |
| Bilgihan, K | 1 |
| Cakir, N | 1 |
| Gökmen, O | 2 |
| Senöz, S | 2 |
| Gülekli, B | 1 |
| Işik, AZ | 2 |
| Zeyneloğlu, HB | 1 |
| Zorlu, CG | 1 |
| Venturoli, S | 2 |
| Marescalchi, O | 1 |
| Colombo, FM | 1 |
| Macrelli, S | 1 |
| Ravaioli, B | 1 |
| Bagnoli, A | 1 |
| Paradisi, R | 1 |
| Flamigni, C | 2 |
| Manusharova, RA | 1 |
| Akalin, S | 1 |
| Sonino, N | 3 |
| Scaroni, C | 1 |
| Biason, A | 1 |
| Boscaro, M | 1 |
| Mantero, F | 1 |
| Conget, JI | 1 |
| Halperin, I | 1 |
| Ferrer, J | 1 |
| González-Clemente, JM | 1 |
| Martinez-Osaba, MJ | 1 |
| Vilardell, E | 1 |
| Fabbri, R | 1 |
| Dal Prato, L | 1 |
| Mantovani, B | 1 |
| Capelli, M | 1 |
| Magrini, O | 1 |
| Weber, MM | 1 |
| Luppa, P | 1 |
| Engelhardt, D | 1 |
| Verhelst, JA | 1 |
| Druwé, P | 1 |
| van Erps, P | 1 |
| Denis, LJ | 1 |
| Mahler, C | 1 |
| Carvalho, D | 1 |
| Pignatelli, D | 1 |
| Resende, C | 1 |
| Martikainen, H | 1 |
| Heikkinen, J | 1 |
| Ruokonen, A | 1 |
| Kauppila, A | 1 |
| Presl, J | 1 |
| De Pedrini, P | 1 |
| Tommaselli, A | 1 |
| Spanò, G | 1 |
| Montemurro, G | 1 |
3 reviews available for ketoconazole and Hirsutism
| Article | Year |
|---|---|
Androgenetic alopecia.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Androgen Antagonists; Biopsy; Comorbidity; Contraindications | 2014 |
[The antimycotic ketoconazole. Indications in prostate disease, hirsutism, precocious puberty and Cushing syndrome?].
Topics: Cushing Syndrome; Hirsutism; Humans; Ketoconazole; Male; Prostatic Diseases; Puberty, Precocious | 1988 |
The endocrine effects of ketoconazole.
Topics: Animals; Breast Neoplasms; Cushing Syndrome; Endocrine System Diseases; Female; Hirsutism; Humans; K | 1986 |
5 trials available for ketoconazole and Hirsutism
| Article | Year |
|---|---|
Ketoconazole therapy: hormonal and clinical effects in non-tumoral hyperandrogenism.
Topics: Acne Vulgaris; Adolescent; Adult; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Hi | 1994 |
Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgen Antagonists; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Contrac | 1996 |
Low dose ketoconazole is an effective and a relatively safe alternative in the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Female; Hirsutism; Hormones; Humans; Ketoconazole; Luteinizing Hormone; | 1996 |
A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism.
Topics: Adult; Cyproterone Acetate; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Hormones; | 1999 |
Effects of ketoconazole in hirsute women.
Topics: Adult; Dehydroepiandrosterone; Double-Blind Method; Estradiol; Female; Hirsutism; Humans; Hydrocorti | 1991 |
14 other studies available for ketoconazole and Hirsutism
| Article | Year |
|---|---|
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectom | 2017 |
Hirsutism.
Topics: Androgen Antagonists; Bromocriptine; Contraceptives, Oral, Combined; Dexamethasone; Female; Finaster | 1994 |
Ketoconazole induced papilledema.
Topics: Adult; Female; Fluorescein Angiography; Fundus Oculi; Hirsutism; Humans; Ketoconazole; Papilledema | 1993 |
[The effect of nizoral on the function of the hypothalamo-hypophyseal-ovarian system in virilism].
Topics: Adolescent; Adult; Drug Evaluation; Female; Hirsutism; Humans; Hypothalamo-Hypophyseal System; Ketoc | 1992 |
Low-dose ketoconazole treatment in hirsute women.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Drug Evaluation; Estradiol; Female; Foll | 1990 |
Evaluation of clinical and hormonal effects in hirsute women treated with ketoconazole.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepi | 1990 |
Ketoconazole therapy for women with acne and/or hirsutism.
Topics: Acne Vulgaris; Adrenocorticotropic Hormone; Adult; Androgens; Estradiol; Estrone; Female; Follicle S | 1990 |
Inhibition of human adrenal androgen secretion by ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Cushing Syndrome; Female | 1989 |
Use of ketoconazole in the treatment of a virilizing adrenocortical carcinoma.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Carcinoma; Female; Gonadal Steroid Hormones; Hirs | 1989 |
Ketoconazole for hirsutism.
Topics: Adult; Female; Hirsutism; Humans; Ketoconazole; Liver | 1985 |
Hormonal and clinical effects of ketoconazole in hirsute women.
Topics: Adult; Androgens; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Hirsutism; Humans; H | 1988 |
[Ketoconazole in the treatment of hirsutism].
Topics: Female; Hirsutism; Humans; Ketoconazole | 1988 |
Clinical and hormonal effects of ketoconazole on hirsutism in women.
Topics: Adolescent; Adult; Androgens; Female; Hirsutism; Humans; Ketoconazole | 1988 |
Current trends in the endocrine use of ketoconazole.
Topics: Chemical Phenomena; Chemistry; Cushing Syndrome; Endocrine System Diseases; Female; Hirsutism; Human | 1988 |