ketoconazole has been researched along with Hemolysis in 4 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our recent study showed that clotrimazole has a relative high affinity for heme, inhibits reduced glutathione-dependent heme catabolism, and enhances heme-induced hemolysis." | 3.71 | Effect of antifungal azoles on the heme detoxification system of malarial parasite. ( Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R, 2002) |
| "which are among the agents of dermatophytosis with high morbidity, produce many virulence factors including hemolysins that exhibit toxic activity on immune system cells." | 1.37 | [Determination of hemolytic activity and in vitro antifungal susceptibility of Trichophyton rubrum clinical strains]. ( Arslan, U; Fındık, D; Solgun, G; Türk Dağı, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Wahab, BF | 1 |
| Awad, GE | 1 |
| Badria, FA | 1 |
| Ghorpade, VS | 1 |
| Yadav, AV | 1 |
| Dias, RJ | 1 |
| Solgun, G | 1 |
| Fındık, D | 1 |
| Türk Dağı, H | 1 |
| Arslan, U | 1 |
| Huy, NT | 1 |
| Kamei, K | 1 |
| Kondo, Y | 1 |
| Serada, S | 1 |
| Kanaori, K | 1 |
| Takano, R | 1 |
| Tajima, K | 1 |
| Hara, S | 1 |
4 other studies available for ketoconazole and Hemolysis
| Article | Year |
|---|---|
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Proliferation; D | 2011 |
Citric acid crosslinked cyclodextrin/hydroxypropylmethylcellulose hydrogel films for hydrophobic drug delivery.
Topics: Antifungal Agents; beta-Cyclodextrins; Citric Acid; Cross-Linking Reagents; Drug Evaluation, Preclin | 2016 |
[Determination of hemolytic activity and in vitro antifungal susceptibility of Trichophyton rubrum clinical strains].
Topics: Antifungal Agents; Econazole; Hair; Hemolysis; Humans; Imidazoles; Itraconazole; Ketoconazole; Micro | 2011 |
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Eryth | 2002 |