ketoconazole has been researched along with Granulomatous Disease, Chronic in 10 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Granulomatous Disease, Chronic: A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with amphotericin B resulted in only moderate improvement of the lesions and was accompanied by considerable toxicity." | 5.28 | Treatment of invasive aspergillosis with itraconazole in a patient with chronic granulomatous disease. ( Raven, EJ; van 't Wout, JW; van der Meer, JW, 1990) |
| "Treatment with amphotericin B resulted in only moderate improvement of the lesions and was accompanied by considerable toxicity." | 1.28 | Treatment of invasive aspergillosis with itraconazole in a patient with chronic granulomatous disease. ( Raven, EJ; van 't Wout, JW; van der Meer, JW, 1990) |
| " The long-term use of trimethoprim-sulfamethoxazole and ketoconazole as a preventive therapy for infections has also been evaluated." | 1.28 | Incidence, severity, and prevention of infections in chronic granulomatous disease. ( Fischer, A; Griscelli, C; Mouy, R; Seger, R; Vilmer, E, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mouy, R | 3 |
| Veber, F | 1 |
| Blanche, S | 1 |
| Donadieu, J | 1 |
| Brauner, R | 1 |
| Levron, JC | 1 |
| Griscelli, C | 3 |
| Fischer, A | 3 |
| Williamson, PR | 1 |
| Kwon-Chung, KJ | 1 |
| Gallin, JI | 1 |
| Crevits, B | 1 |
| Van der Straeten, E | 1 |
| Naeyaert, JM | 1 |
| Van Hecke, E | 1 |
| Kint, A | 1 |
| Kloss, S | 1 |
| Schuster, A | 1 |
| Schroten, H | 1 |
| Lamprecht, J | 2 |
| Wahn, V | 1 |
| van 't Wout, JW | 1 |
| Raven, EJ | 1 |
| van der Meer, JW | 1 |
| Kühn, AG | 1 |
| Sauer, S | 1 |
| Neijens, HJ | 1 |
| Frenkel, J | 1 |
| de Muinck Keizer-Schrama, SM | 1 |
| Dzoljic-Danilovic, G | 1 |
| Meradji, M | 1 |
| van Dongen, JJ | 1 |
| Vilmer, E | 2 |
| Seger, R | 1 |
| Bremard, C | 1 |
| Huu Trong, P | 1 |
1 review available for ketoconazole and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Successful treatment of Paecilomyces varioti infection in a patient with chronic granulomatous disease and a review of Paecilomyces species infections.
Topics: Amphotericin B; Antifungal Agents; Child; Drug Therapy, Combination; Follow-Up Studies; Granulomatou | 1992 |
1 trial available for ketoconazole and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Long-term itraconazole prophylaxis against Aspergillus infections in thirty-two patients with chronic granulomatous disease.
Topics: Administration, Oral; Aspergillosis; Child; Child, Preschool; Female; Follow-Up Studies; Granulomato | 1994 |
8 other studies available for ketoconazole and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Resistance to ketoconazole.
Topics: Candida albicans; Drug Resistance, Microbial; Granulomatous Disease, Chronic; Humans; Imidazoles; Im | 1982 |
[Chronic aspergillosis in familial chronic granulomatosis].
Topics: Adult; Antifungal Agents; Aspergillosis; Dermatomycoses; Fingers; Granulomatous Disease, Chronic; Hu | 1992 |
Control of proven pulmonary and suspected CNS aspergillus infection with itraconazole in a patient with chronic granulomatous disease.
Topics: Antifungal Agents; Aspergillosis; Brain Diseases; Child; Granulomatous Disease, Chronic; Humans; Itr | 1991 |
Treatment of invasive aspergillosis with itraconazole in a patient with chronic granulomatous disease.
Topics: Adolescent; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Chromatography, High Pressure Liqu | 1990 |
[Aspergillus mastoiditis in infected granulomatosis--a case report].
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Child; Combined Modality Therapy; Granuloma | 1990 |
Invasive Aspergillus infection in chronic granulomatous disease: treatment with itraconazole.
Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus nidulans; Granulomatous Disease, Chronic; Human | 1989 |
Incidence, severity, and prevention of infections in chronic granulomatous disease.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Genetic Linkage; Granu | 1989 |
[Aspergillus infection and chronic septic granulomatosis].
Topics: Adolescent; Amphotericin B; Aspergillosis; Child; Child, Preschool; Female; Granulomatous Disease, C | 1985 |