ketoconazole has been researched along with Gingival Overgrowth in 1 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Gingival Overgrowth: Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nifedipine (NIF), a calcium channel blocker, is well known to induce gingival overgrowth (GO) as an adverse effect, and ketoconazole (KTZ), an azole antifungal agent, has been implicated in various drug interactions." | 7.73 | Enhancement of nifedipine-induced gingival overgrowth by concomitant ketoconazole in rats. ( Amano, A; Kamisaki, Y; Kato, T; Morisaki, I, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, T | 1 |
| Amano, A | 1 |
| Kamisaki, Y | 1 |
| Morisaki, I | 1 |
1 other study available for ketoconazole and Gingival Overgrowth
| Article | Year |
|---|---|
Enhancement of nifedipine-induced gingival overgrowth by concomitant ketoconazole in rats.
Topics: Animals; Antifungal Agents; Calcium Channel Blockers; Drug Synergism; Gingival Overgrowth; Ketoconaz | 2005 |