ketoconazole has been researched along with Fatigue in 4 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etoposide is a widely used cytotoxic drug that is commercially available in both intravenous and oral formulations." | 2.73 | Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer. ( Desai, AA; Fleming, GF; House, L; Innocenti, F; Kobayashi, K; Ramirez, J; Ratain, MJ; Schilsky, RL; Shepard, D; Vogelzang, NJ; Yong, WP, 2007) |
| "The median time to disease progression or dose escalation on LDK was 3." | 1.33 | Response to low-dose ketoconazole and subsequent dose escalation to high-dose ketoconazole in patients with androgen-independent prostate cancer. ( Jackman, DM; Kantoff, PW; Nakabayashi, M; Oh, WK; Regan, MM; Xie, W, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karniadakis, I | 1 |
| Garoufalia, Z | 1 |
| Kouskos, E | 1 |
| Mantas, D | 1 |
| Nakabayashi, M | 1 |
| Xie, W | 1 |
| Regan, MM | 1 |
| Jackman, DM | 1 |
| Kantoff, PW | 1 |
| Oh, WK | 1 |
| Yong, WP | 1 |
| Desai, AA | 1 |
| Innocenti, F | 1 |
| Ramirez, J | 1 |
| Shepard, D | 1 |
| Kobayashi, K | 1 |
| House, L | 1 |
| Fleming, GF | 1 |
| Vogelzang, NJ | 1 |
| Schilsky, RL | 1 |
| Ratain, MJ | 1 |
| Farschian, M | 1 |
| Yaghoobi, R | 1 |
| Samadi, K | 1 |
2 trials available for ketoconazole and Fatigue
| Article | Year |
|---|---|
Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifungal Agents; Antineoplastic Agents, Phyt | 2007 |
Fluconazole versus ketoconazole in the treatment of tinea versicolor.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Double-Blind Method; Drug Administration | 2002 |
2 other studies available for ketoconazole and Fatigue
| Article | Year |
|---|---|
Pancreatic adenocarcinoma presenting with Cushing's syndrome.
Topics: 14-alpha Demethylase Inhibitors; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Diagnosis, Dif | 2021 |
Response to low-dose ketoconazole and subsequent dose escalation to high-dose ketoconazole in patients with androgen-independent prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Disease Progress | 2006 |