ketoconazole has been researched along with Eye Infections, Fungal in 33 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Eye Infections, Fungal: Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis." | 9.24 | Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial. ( Agarwal, T; Maharana, PK; Satpathy, G; Sharma, N; Singhal, D; Sinha, R; Titiyal, JS; Upadhyay, AD; Velpandian, T, 2017) |
| "To evaluate clinical signs of ocular blastomycosis in dogs, to determine response of blastomycosis-infected eyes to treatment with systemically administered amphotericin B and ketoconazole, and to identify prognostic indicators of successful antifungal treatment." | 7.69 | Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985-1993). ( Bloom, JD; Gerding, PA; Hamor, RE, 1996) |
| "Fungal keratitis is a rare but serious condition that may result in loss of vision." | 5.33 | Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis. ( Ayala-Lugo, R; Barbosa, L; de Kaspar, HM; Sanchez-Di Martino, D; Sonego-Krone, S; Ta, CN; Torres-Alvariza, G, 2006) |
| "Ketoconazole therapy was well tolerated by the dog." | 5.28 | Ketoconazole therapy in a dog with systemic cryptococcosis. ( Bachrach, A; Labato, MA; Mason, GD, 1989) |
| "To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis." | 5.24 | Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial. ( Agarwal, T; Maharana, PK; Satpathy, G; Sharma, N; Singhal, D; Sinha, R; Titiyal, JS; Upadhyay, AD; Velpandian, T, 2017) |
| ", itraconazole, voriconazole, ketoconazole, econazole and clotrimazole were investigated in order to evaluate their efficacy against filamentous fungi isolated from mycotic keratitis." | 3.81 | In vitro susceptibility of filamentous fungi from mycotic keratitis to azole drugs. ( Babu Singh, YR; Galgóczy, L; Homa, M; Kredics, L; Manikandan, P; Mythili, A; Narendran, V; Panneerselvam, K; Priya, R; Shobana, CS; Vágvölgyi, C, 2015) |
| " A prolonged treatment by ketoconazole had a successful resolution in 70% of cases; 1 case of ciliar tinea caused by Trichophyton violaceum." | 3.71 | [Ocular parasitoses and mycoses: cases diagnosed in the Central University Hospital of Sfax between 1996 and 1999]. ( Ayadi, A; Ben Zina, Z; Cheikh-Rouhou, F; Ghorbel, R; Makni, F, 2001) |
| "To evaluate clinical signs of ocular blastomycosis in dogs, to determine response of blastomycosis-infected eyes to treatment with systemically administered amphotericin B and ketoconazole, and to identify prognostic indicators of successful antifungal treatment." | 3.69 | Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985-1993). ( Bloom, JD; Gerding, PA; Hamor, RE, 1996) |
| "Ketoconazole was used in the form of tablets and instillations." | 2.67 | [Imidazoles in the treatment of ocular mycoses]. ( Diadina, UV; Lapshina, NA; Maĭchuk, IuF, 1991) |
| "Keratitis is a major cause of avoidable visual impairment." | 1.46 | Condition responsive nanoparticles for managing infection and inflammation in keratitis. ( Ahsan, SM; Rao, CM, 2017) |
| "Mycetomas are pathological processes through which exogenous fungal or actinomycotic etiological agents produce grains." | 1.39 | [Orbital mycetoma: a case report]. ( Agboton, G; Diakhaté, M; Dieng, M; Dieng, MT; Diop, Y; Gueye, NN; Ndiaye Sow, MN; Seck, SM, 2013) |
| "Acanthamoeba keratitis is a rare but severe corneal infection which, despite improvements in diagnosis and treatment, still culminates in prolonged morbidity and significant loss of visual acuity." | 1.34 | [Acanthamoeba keratitis: about the first two Tunisian cases]. ( Ayadi, A; Ben Salah, S; Ben Zina, Z; Cheikrouhou, F; Colin, J; Feki, J; Makni, F; Mlik, M, 2007) |
| "Ketoconazole may cause severe anaphylactic shock even when taken orally." | 1.33 | Refractory anaphylactic shock associated with ketoconazole treatment. ( Chen, JH; Lee, CH; Lin, LJ; Liu, PY, 2005) |
| "Fungal keratitis is a rare but serious condition that may result in loss of vision." | 1.33 | Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis. ( Ayala-Lugo, R; Barbosa, L; de Kaspar, HM; Sanchez-Di Martino, D; Sonego-Krone, S; Ta, CN; Torres-Alvariza, G, 2006) |
| "A case of cryptococcal meningitis with unilateral paresis of the superior division of the oculomotor nerve was reported." | 1.28 | Superior division paresis of the oculomotor nerve caused by cryptococcal meningitis. ( Chotmongkol, V; Techasuknirun, A, 1992) |
| "Ketoconazole therapy was well tolerated by the dog." | 1.28 | Ketoconazole therapy in a dog with systemic cryptococcosis. ( Bachrach, A; Labato, MA; Mason, GD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.06) | 18.7374 |
| 1990's | 13 (39.39) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Y | 1 |
| Pang, G | 1 |
| Zhao, D | 1 |
| Gao, C | 1 |
| Zhou, L | 1 |
| Sun, S | 1 |
| Wang, B | 1 |
| Ahsan, SM | 1 |
| Rao, CM | 1 |
| Sharma, N | 2 |
| Singhal, D | 2 |
| Maharana, PK | 3 |
| Sinha, R | 2 |
| Agarwal, T | 2 |
| Upadhyay, AD | 1 |
| Velpandian, T | 2 |
| Satpathy, G | 2 |
| Titiyal, JS | 3 |
| Sahay, P | 2 |
| Asif, MI | 1 |
| Saluja, G | 1 |
| Bandivadekar, P | 1 |
| Chako, J | 1 |
| Espósito, E | 1 |
| Maccio, JP | 1 |
| Monti, R | 1 |
| Cervi, L | 1 |
| Serra, HM | 1 |
| Urrets-Zavalía, JA | 1 |
| Mandour, SS | 1 |
| Marey, HM | 1 |
| Farahat, HG | 1 |
| Shobana, CS | 1 |
| Mythili, A | 1 |
| Homa, M | 1 |
| Galgóczy, L | 1 |
| Priya, R | 1 |
| Babu Singh, YR | 1 |
| Panneerselvam, K | 1 |
| Vágvölgyi, C | 1 |
| Kredics, L | 1 |
| Narendran, V | 1 |
| Manikandan, P | 1 |
| Gueye, NN | 1 |
| Seck, SM | 1 |
| Diop, Y | 1 |
| Ndiaye Sow, MN | 1 |
| Agboton, G | 1 |
| Diakhaté, M | 1 |
| Dieng, M | 1 |
| Dieng, MT | 1 |
| Guarro, J | 1 |
| Höfling-Lima, AL | 1 |
| Gené, J | 1 |
| De Freitas, D | 1 |
| Godoy, P | 1 |
| Zorat-Yu, ML | 1 |
| Zaror, L | 1 |
| Fischman, O | 1 |
| Miguélez, S | 1 |
| Obrador, P | 1 |
| Vila, J | 1 |
| Garg, P | 1 |
| Mahesh, S | 1 |
| Bansal, AK | 1 |
| Gopinathan, U | 1 |
| Rao, GN | 1 |
| Liu, PY | 1 |
| Lee, CH | 1 |
| Lin, LJ | 1 |
| Chen, JH | 1 |
| Sonego-Krone, S | 1 |
| Sanchez-Di Martino, D | 1 |
| Ayala-Lugo, R | 1 |
| Torres-Alvariza, G | 1 |
| Ta, CN | 1 |
| Barbosa, L | 1 |
| de Kaspar, HM | 1 |
| Panda, A | 1 |
| Das, H | 1 |
| Deb, M | 1 |
| Khanal, B | 1 |
| Kumar, S | 1 |
| Ben Salah, S | 1 |
| Makni, F | 2 |
| Cheikrouhou, F | 1 |
| Ben Zina, Z | 2 |
| Mlik, M | 1 |
| Feki, J | 1 |
| Colin, J | 1 |
| Ayadi, A | 2 |
| Kanavi, MR | 1 |
| Foroutan, AR | 1 |
| Kamel, MR | 1 |
| Afsar, N | 1 |
| Javadi, MA | 1 |
| Bloom, JD | 1 |
| Hamor, RE | 1 |
| Gerding, PA | 1 |
| Perlman, EM | 1 |
| Binns, L | 1 |
| Brooks, DE | 1 |
| Andrew, SE | 1 |
| Dillavou, CL | 1 |
| Ellis, G | 1 |
| Kubilis, PS | 1 |
| Roodhooft, J | 1 |
| van Rens, G | 1 |
| Bogaerts, M | 1 |
| Vermander, JM | 1 |
| Cheikh-Rouhou, F | 1 |
| Ghorbel, R | 1 |
| O'Day, DM | 1 |
| Head, WS | 1 |
| Robinson, RD | 1 |
| Williams, TE | 1 |
| Gedde, S | 1 |
| Carlson, AN | 1 |
| Foulks, GN | 1 |
| Perfect, JR | 1 |
| Kim, JH | 1 |
| Bloom, PA | 1 |
| Laidlaw, DA | 1 |
| Easty, DL | 2 |
| Warnock, DW | 1 |
| Chotmongkol, V | 1 |
| Techasuknirun, A | 1 |
| Maskin, SL | 1 |
| Alfonso, E | 1 |
| Maĭchuk, IuF | 1 |
| Lapshina, NA | 1 |
| Diadina, UV | 1 |
| Coriglione, G | 1 |
| Stella, G | 1 |
| Gafa, L | 1 |
| Spata, G | 1 |
| Oliveri, S | 1 |
| Padhye, AA | 1 |
| Ajello, L | 1 |
| Ragge, NK | 1 |
| Hart, JC | 1 |
| Tyers, AG | 1 |
| Brod, RD | 1 |
| Flynn, HW | 1 |
| Clarkson, JG | 1 |
| Pflugfelder, SC | 1 |
| Culbertson, WW | 1 |
| Miller, D | 1 |
| Singh, SM | 1 |
| Khan, R | 1 |
| Sharma, S | 1 |
| Chatterjee, PK | 1 |
| Mason, GD | 1 |
| Labato, MA | 1 |
| Bachrach, A | 1 |
2 trials available for ketoconazole and Eye Infections, Fungal
| Article | Year |
|---|---|
Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Antifungal Agents; Chemotherapy, Adjuvan | 2017 |
[Imidazoles in the treatment of ocular mycoses].
Topics: Administration, Oral; Aspergillosis; Candidiasis; Eye Infections, Fungal; Humans; Ketoconazole; Opht | 1991 |
31 other studies available for ketoconazole and Eye Infections, Fungal
| Article | Year |
|---|---|
In vitro activity of thimerosal against ocular pathogenic fungi.
Topics: Alternaria; Amphotericin B; Antifungal Agents; Aspergillus; Eye Infections, Fungal; Fungi; Fusarium; | 2010 |
Condition responsive nanoparticles for managing infection and inflammation in keratitis.
Topics: Animals; Antibodies; Antifungal Agents; Cells, Cultured; Cornea; Drug Delivery Systems; Eye Infectio | 2017 |
Periocular contact dermatitis with use of topical voriconazole 1% in mycotic keratitis.
Topics: Administration, Oral; Adult; Antifungal Agents; Aspergillus flavus; Corneal Ulcer; Dermatitis, Conta | 2018 |
Management Algorithm for Fungal Keratitis: The TST (Topical, Systemic, and Targeted Therapy) Protocol.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Antifungal Agents; Chi | 2019 |
Alternaria keratitis and hypopyon after clear-cornea phacoemulsification.
Topics: Abscess; Administration, Oral; Aged; Alternaria; Alternariosis; Amphotericin B; Antifungal Agents; C | 2014 |
Resistant Microbial Keratitis in South Nile Delta, Egypt: Influence of Regional Risk Factors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Child; Child, Preschool | 2016 |
In vitro susceptibility of filamentous fungi from mycotic keratitis to azole drugs.
Topics: Antifungal Agents; Azoles; Corneal Ulcer; Drug Resistance, Fungal; Eye Infections, Fungal; Fungi; Hu | 2015 |
[Orbital mycetoma: a case report].
Topics: Adolescent; Antifungal Agents; Exophthalmos; Eye Enucleation; Eye Infections, Fungal; Humans; Ketoco | 2013 |
Corneal ulcer caused by the new fungal species Sarcopodium oculorum.
Topics: Antifungal Agents; Child; Corneal Ulcer; Eye Infections, Fungal; Humans; Keratitis; Ketoconazole; Ma | 2002 |
[Conjunctival infection due to penicillium SP].
Topics: Aged; Amphotericin B; Antifungal Agents; Conjunctivitis; Eye Infections, Fungal; Humans; Ketoconazol | 2003 |
Fungal infection of sutureless self-sealing incision for cataract surgery.
Topics: Aged; Aged, 80 and over; Amphotericin B; Aspergillosis; Candidiasis; Corneal Ulcer; Drug Therapy, Co | 2003 |
Refractory anaphylactic shock associated with ketoconazole treatment.
Topics: Aged; Anaphylaxis; Antifungal Agents; Candidiasis; Eye Infections, Fungal; Female; Humans; Hypotensi | 2005 |
Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Child; Drug The | 2006 |
Aureobasidium pullulans keratitis.
Topics: Ascomycota; Corneal Ulcer; Eye Infections, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoco | 2006 |
[Acanthamoeba keratitis: about the first two Tunisian cases].
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Amebicides; Animals; Antifungal Agents; Benzamidines; B | 2007 |
Candida interface keratitis after deep anterior lamellar keratoplasty: clinical, microbiologic, histopathologic, and confocal microscopic reports.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis; Cornea; C | 2007 |
Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985-1993).
Topics: Amphotericin B; Animals; Antifungal Agents; Blastomycosis; Dog Diseases; Dogs; Drug Therapy, Combina | 1996 |
Intense photophobia caused by Arthrographis kalrae in a contact lens-wearing patient.
Topics: Administration, Oral; Amphotericin B; Antifungal Agents; Contact Lenses; Cornea; Eye Infections, Fun | 1997 |
Antimicrobial susceptibility patterns of fungi isolated from horses with ulcerative keratomycosis.
Topics: Analysis of Variance; Animals; Antifungal Agents; Aspergillus; Cornea; Corneal Ulcer; Drug Resistanc | 1998 |
Infectious crystalline keratopathy: a case report.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Conjunctiva; Cornea; Corneal Diseases; Diagnosis, D | 1998 |
[Ocular parasitoses and mycoses: cases diagnosed in the Central University Hospital of Sfax between 1996 and 1999].
Topics: Adolescent; Adult; Alternaria; Animals; Aspergillus; Candida albicans; Eye Infections, Fungal; Eye I | 2001 |
The evaluation of therapeutic responses in experimental keratomycosis.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count | 1992 |
Fungal scleritis after cataract surgery. Successful outcome using itraconazole.
Topics: Administration, Oral; Antifungal Agents; Aspergillosis; Aspergillus flavus; Cataract Extraction; Eye | 1992 |
Treatment failure in a case of fungal keratitis caused by Pseudallescheria boydii.
Topics: Antifungal Agents; Eye Infections, Fungal; Humans; Itraconazole; Keratitis; Keratoplasty, Penetratin | 1992 |
Superior division paresis of the oculomotor nerve caused by cryptococcal meningitis.
Topics: Adolescent; Antifungal Agents; Blepharoptosis; Eye Infections, Fungal; Female; Humans; Itraconazole; | 1992 |
Fungal keratitis after radial keratotomy.
Topics: Adult; Amphotericin B; Candidiasis; Eye Infections, Fungal; Female; Humans; Keratitis; Keratotomy, R | 1992 |
Neosartorya fischeri var fischeri (Wehmer) Malloch and Cain 1972 (anamorph: Aspergillus fischerianus Samson and Gams 1985) as a cause of mycotic keratitis.
Topics: Aspergillosis; Aspergillus; Cornea; Eye Enucleation; Eye Infections, Fungal; Humans; Keratitis; Keto | 1990 |
A case of fungal keratitis caused by Scopulariopsis brevicaulis: treatment with antifungal agents and penetrating keratoplasty.
Topics: Adult; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Eye Infections, Fungal; Humans; | 1990 |
Endogenous Candida endophthalmitis. Management without intravenous amphotericin B.
Topics: Adult; Aged; Amphotericin B; Candida; Candida albicans; Candidiasis; Endophthalmitis; Eye Infections | 1990 |
Clinical and experimental mycotic corneal ulcer caused by Aspergillus fumigatus and the effect of oral ketoconazole in the treatment.
Topics: Administration, Oral; Animals; Aspergillosis; Aspergillus fumigatus; Child; Corneal Ulcer; Disease M | 1989 |
Ketoconazole therapy in a dog with systemic cryptococcosis.
Topics: Animals; Chorioretinitis; Cryptococcosis; Diagnosis, Differential; Dog Diseases; Dogs; Eye Infection | 1989 |