ketoconazole has been researched along with Experimental Mammary Neoplasms in 2 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats bearing mammary carcinomas induced by N-nitroso-N-methylurea (NMU) were subjected to either no treatment (C), to ovariectomy (O), to continuous ketoconazole dosing at 400 ppm into the diet (K) or to both ovariectomy and ketoconazole dosing (O + K)." | 1.27 | Effect of a high dosage of ketoconazole all or not combined with ovariectomy on N-nitroso-N-methylurea-induced mammary cancer in the rat. ( de Coster, R; Hérin, V; Marsboom, R; van Cauteren, H; van den Berghe, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, JB | 1 |
| Huynh, CK | 1 |
| Handratta, VD | 1 |
| Gediya, LK | 1 |
| Brodie, AM | 1 |
| Goloubeva, OG | 1 |
| Clement, OO | 1 |
| Nanne, IP | 1 |
| Soprano, DR | 1 |
| Njar, VC | 1 |
| van Cauteren, H | 1 |
| van den Berghe, J | 1 |
| Hérin, V | 1 |
| de Coster, R | 1 |
| Marsboom, R | 1 |
2 other studies available for ketoconazole and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cricetinae; Cytochrome P-450 Enzyme Inhibitors; Cy | 2004 |
Effect of a high dosage of ketoconazole all or not combined with ovariectomy on N-nitroso-N-methylurea-induced mammary cancer in the rat.
Topics: Animals; Castration; Combined Modality Therapy; Female; Ketoconazole; Mammary Neoplasms, Experimenta | 1984 |