Page last updated: 2024-10-29

ketoconazole and Experimental Hepatoma

ketoconazole has been researched along with Experimental Hepatoma in 6 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
"albicans can alter the ability of murine B16 melanoma (B16M) cells to colonize the liver."1.36Candida albicans enhances experimental hepatic melanoma metastasis. ( de Cerio, AA; Gallot, N; Hernando, FL; Martínez-de-Tejada, G; Mendoza, L; Rodríguez-Cuesta, J; Vidal-Vanaclocha, F, 2010)
"Ketoconazole is an oral-antifungal agent that has been used worldwide in the treatment of some hormone-dependent human cancer."1.31Ketoconazole induces G0/G1 arrest in human colorectal and hepatocellular carcinoma cell lines. ( Chaing, CC; Chen, RJ; Ho, YS; Hsieh, JY; Lee, WS; Liang, YC; Lin, CH; Lin, JK; Wang, YJ, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodríguez-Cuesta, J1
Hernando, FL1
Mendoza, L1
Gallot, N1
de Cerio, AA1
Martínez-de-Tejada, G1
Vidal-Vanaclocha, F1
Korashy, HM1
Brocks, DR1
El-Kadi, AO1
Parker, RA1
Pearce, BC1
Clark, RW1
Gordon, DA1
Wright, JJ1
Chen, RJ1
Lee, WS1
Liang, YC1
Lin, JK1
Wang, YJ1
Lin, CH1
Hsieh, JY1
Chaing, CC1
Ho, YS1
Tam, SP1
Leighton, JK1
Dueland, S1
Straka, MS1
Trawick, J1
Davis, RA1

Other Studies

6 other studies available for ketoconazole and Experimental Hepatoma

ArticleYear
Candida albicans enhances experimental hepatic melanoma metastasis.
    Clinical & experimental metastasis, 2010, Volume: 27, Issue:1

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Humans; Inflammation Mediators; Interleuk

2010
Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection.
    Cancer letters, 2007, Dec-08, Volume: 258, Issue:1

    Topics: Animals; Antifungal Agents; Carcinoma, Hepatocellular; Enzyme Activation; Enzyme Induction; Fluconaz

2007
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell L

1993
Ketoconazole induces G0/G1 arrest in human colorectal and hepatocellular carcinoma cell lines.
    Toxicology and applied pharmacology, 2000, Dec-01, Volume: 169, Issue:2

    Topics: Animals; Antifungal Agents; Blotting, Western; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Ce

2000
Effects of gemfibrozil and ketoconazole on human apolipoprotein AI, B and E levels in two hepatoma cell lines, HepG2 and Hep3B.
    Atherosclerosis, 1991, Volume: 91, Issue:1-2

    Topics: Albumins; Animals; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Apolipoproteins E; Cell L

1991
Activation of the silent endogenous cholesterol-7-alpha-hydroxylase gene in rat hepatoma cells: a new complementation group having resistance to 25-hydroxycholesterol.
    Molecular and cellular biology, 1991, Volume: 11, Issue:4

    Topics: Animals; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Dexamethasone; Drug Resistance; Gene Expressi

1991