ketoconazole has been researched along with Esophagitis in 17 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the clinical and endoscopic response of candida esophagitis to antifungal therapy and to compare the two oral antifungal agents, fluconazole and ketoconazole." | 9.07 | Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in AIDS. A randomized trial. ( Conteas, CN; Dretler, RH; Islam, MZ; Koster, FM; Laine, L; Sattler, F; Squires, K; Tuazon, C, 1992) |
| "Ketoconazole, a new oral antifungal agent, was evaluated in the treatment of four patients with severe chronic mucocutaneous candidiasis refractory to standard antifungal therapy." | 9.05 | Successful treatment of chronic mucocutaneous candidiasis with ketoconazole. ( Ament, ME; Byrne, W; Graybill, J; Rosenblatt, HM; Stiehm, ER, 1980) |
| "Although ketoconazole has been shown to be effective in treating esophageal candidiasis in other immunodeficiency states, similar studies have not been reported in patients with acquired immunodeficiency syndrome." | 7.67 | Ketoconazole-resistant Candida esophagitis in patients with acquired immunodeficiency syndrome. ( Dincsoy, HP; Raufman, JP; Rosenthal, LE; Tavitian, A; Webber, CA; Weber, J, 1986) |
| "Ketoconazole in this study was universally effective." | 5.27 | Ketoconazole treatment of Candida esophagitis--a prospective study of 12 cases. ( Arsura, EL; Fazio, RA; Wickremesinghe, PC, 1983) |
| "Ketoconazole is a synthetic imidazole derivative indicated in the treatment of superficial and deep mycoses (1)." | 5.27 | Persistent oesophageal candidiasis treated with ketoconazole. ( MacLeod, MD, 1983) |
| "After the first episode of esophageal candidiasis, 122 consecutive AIDS patients were randomly assigned to two different regimens of continuous long-term antifungal prophylaxis (ketoconazole 200 mg or fluconazole 50 mg/day p." | 5.07 | Prevention of symptomatic recurrences of esophageal candidiasis in AIDS patients after the first episode: a prospective open study. ( Antinori, S; Ardizzone, S; Bianchi Porro, G; Cernuschi, M; Esposito, R; Lazzarin, A; Moroni, M; Parente, F, 1994) |
| "To determine the clinical and endoscopic response of candida esophagitis to antifungal therapy and to compare the two oral antifungal agents, fluconazole and ketoconazole." | 5.07 | Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in AIDS. A randomized trial. ( Conteas, CN; Dretler, RH; Islam, MZ; Koster, FM; Laine, L; Sattler, F; Squires, K; Tuazon, C, 1992) |
| "Ketoconazole, a new oral antifungal agent, was evaluated in the treatment of four patients with severe chronic mucocutaneous candidiasis refractory to standard antifungal therapy." | 5.05 | Successful treatment of chronic mucocutaneous candidiasis with ketoconazole. ( Ament, ME; Byrne, W; Graybill, J; Rosenblatt, HM; Stiehm, ER, 1980) |
| "Although ketoconazole has been shown to be effective in treating esophageal candidiasis in other immunodeficiency states, similar studies have not been reported in patients with acquired immunodeficiency syndrome." | 3.67 | Ketoconazole-resistant Candida esophagitis in patients with acquired immunodeficiency syndrome. ( Dincsoy, HP; Raufman, JP; Rosenthal, LE; Tavitian, A; Webber, CA; Weber, J, 1986) |
| "Viral esophagitis was identified in 13 cases (eight herpes simplex virus and five cytomegalovirus), and an esophagitis of unknown origin was documented in two patients." | 1.28 | Opportunistic infections of the esophagus not responding to oral systemic antifungals in patients with AIDS: their frequency and treatment. ( Bianchi Porro, G; Cernuschi, M; Lazzarin, A; Parente, F; Rizzardini, G; Valsecchi, L, 1991) |
| "Ketoconazole in this study was universally effective." | 1.27 | Ketoconazole treatment of Candida esophagitis--a prospective study of 12 cases. ( Arsura, EL; Fazio, RA; Wickremesinghe, PC, 1983) |
| "Ketoconazole is a synthetic imidazole derivative indicated in the treatment of superficial and deep mycoses (1)." | 1.27 | Persistent oesophageal candidiasis treated with ketoconazole. ( MacLeod, MD, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosenblatt, HM | 1 |
| Byrne, W | 1 |
| Ament, ME | 1 |
| Graybill, J | 1 |
| Stiehm, ER | 1 |
| Fazio, RA | 1 |
| Wickremesinghe, PC | 1 |
| Arsura, EL | 1 |
| MacLeod, MD | 1 |
| Parente, F | 2 |
| Ardizzone, S | 1 |
| Cernuschi, M | 2 |
| Antinori, S | 1 |
| Esposito, R | 1 |
| Moroni, M | 1 |
| Lazzarin, A | 2 |
| Bianchi Porro, G | 2 |
| Neely, D | 1 |
| Berman, DS | 1 |
| Wenglin, BD | 1 |
| Legg, JJ | 1 |
| Brossier, KA | 1 |
| Goldschmidt, RH | 1 |
| Thio, CL | 1 |
| Rutledge, TM | 1 |
| Ali, A | 1 |
| Rünzi, M | 1 |
| Rosien, U | 1 |
| Goebell, H | 1 |
| Layer, P | 1 |
| Mascarenhas, MR | 1 |
| McGowan, KL | 1 |
| Ruchelli, E | 1 |
| Athreya, B | 1 |
| Altschuler, SM | 1 |
| Ustianowski, AP | 1 |
| Leake, H | 1 |
| Evans, S | 1 |
| Laine, L | 1 |
| Dretler, RH | 1 |
| Conteas, CN | 1 |
| Tuazon, C | 1 |
| Koster, FM | 1 |
| Sattler, F | 1 |
| Squires, K | 1 |
| Islam, MZ | 1 |
| Rizzardini, G | 1 |
| Valsecchi, L | 1 |
| Wilcox, CM | 1 |
| Diehl, DL | 1 |
| Cello, JP | 1 |
| Margaretten, W | 1 |
| Jacobson, MA | 1 |
| Clotet, B | 1 |
| Casals, A | 1 |
| Reverter, J | 1 |
| Planas, R | 1 |
| Boix, J | 1 |
| Gimenez, J | 1 |
| Jou, A | 1 |
| Tor, J | 1 |
| Foz, M | 1 |
| Tavitian, A | 1 |
| Raufman, JP | 1 |
| Rosenthal, LE | 1 |
| Weber, J | 1 |
| Webber, CA | 1 |
| Dincsoy, HP | 1 |
| Rao, SP | 1 |
| Hammerschlag, MR | 1 |
| Walk, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Comparative Multicenter Trial of Fluconazole and Ketoconazole in the Treatment of Esophageal Candidiasis in Immunocompromised Patients[NCT00002304] | 0 participants | Interventional | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for ketoconazole and Esophagitis
| Article | Year |
|---|---|
Successful treatment of chronic mucocutaneous candidiasis with ketoconazole.
Topics: Adult; Antifungal Agents; Candida; Candidiasis; Candidiasis, Chronic Mucocutaneous; Child; Clinical | 1980 |
Prevention of symptomatic recurrences of esophageal candidiasis in AIDS patients after the first episode: a prospective open study.
Topics: Adult; AIDS-Related Opportunistic Infections; Candidiasis; Esophagitis; Female; Fluconazole; Follow- | 1994 |
Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in AIDS. A randomized trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis; Double-Blind Method; Esophagitis; Esophagosc | 1992 |
14 other studies available for ketoconazole and Esophagitis
| Article | Year |
|---|---|
Ketoconazole treatment of Candida esophagitis--a prospective study of 12 cases.
Topics: Adult; Aged; Candidiasis; Endoscopy; Esophagitis; Female; Humans; Imidazoles; Ketoconazole; Male; Mi | 1983 |
Persistent oesophageal candidiasis treated with ketoconazole.
Topics: Candidiasis; Esophagitis; Humans; Ketoconazole; Male; Middle Aged | 1983 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Cost-effective treatment of Candida esophagitis.
Topics: AIDS-Related Opportunistic Infections; Candidiasis; Esophagitis; Humans; Ketoconazole | 1993 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Drug Costs; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Lichen planus esophagitis with secondary candidiasis: successful combination treatment with ketoconazole and a corticosteroid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candidiasis; Drug Therapy, Combination; | 1996 |
Acremonium infection of the esophagus.
Topics: Acremonium; Barrett Esophagus; Child, Preschool; Cimetidine; Connective Tissue Diseases; Esophageal | 1997 |
Outpatient therapy of HIV-associated oral and oesophageal candidosis.
Topics: AIDS-Related Opportunistic Infections; Ambulatory Care; Amphotericin B; Antifungal Agents; Candidias | 1997 |
Opportunistic infections of the esophagus not responding to oral systemic antifungals in patients with AIDS: their frequency and treatment.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Administration, Oral; Adult; Amphotericin B; Antifung | 1991 |
Cytomegalovirus esophagitis in patients with AIDS. A clinical, endoscopic, and pathologic correlation.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Cytomegalovirus Infections; Diagnosis, Differenti | 1990 |
Candida esophagitis in patients infected by human immune deficiency virus: treatment and prognostic significance.
Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Esophagitis; Humans; Ketoconazole; Prognosis | 1988 |
Ketoconazole-resistant Candida esophagitis in patients with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candida albicans; Candidiasis; Drug Resistance, Microbial | 1986 |
Candida esophagitis in two children with acute leukemia: successful therapy with ketoconazole.
Topics: Amphotericin B; Candidiasis, Cutaneous; Candidiasis, Oral; Child; Esophagitis; Female; Humans; Ketoc | 1985 |