ketoconazole has been researched along with Erectile Dysfunction in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Erectile Dysfunction: The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The median time to reach the C(max) was delayed in the co-administrated treatment, while the mean terminal elimination half-life (t(1/2)) remained relatively unchanged regardless of ketoconazole co-administration." | 2.75 | Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects. ( Cho, JY; Chung, YJ; Jang, IJ; Kim, BH; Kim, HS; Kim, TE; Shin, KH; Shin, SG; Yu, KS, 2010) |
| "Seven patients with HFP were treated with AB." | 1.36 | Androgen blockade for the treatment of high-flow priapism. ( Chi, T; Lue, TF; Mwamukonda, KB; Shindel, AW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, KH | 1 |
| Chung, YJ | 1 |
| Kim, BH | 1 |
| Kim, TE | 1 |
| Kim, HS | 1 |
| Cho, JY | 1 |
| Jang, IJ | 1 |
| Shin, SG | 1 |
| Yu, KS | 1 |
| Mwamukonda, KB | 1 |
| Chi, T | 1 |
| Shindel, AW | 1 |
| Lue, TF | 1 |
| Pont, A | 1 |
| Graybill, JR | 1 |
| Craven, PC | 1 |
| Galgiani, JN | 1 |
| Dismukes, WE | 1 |
| Reitz, RE | 1 |
| Stevens, DA | 1 |
| Beeley, L | 1 |
| Peppas, DS | 1 |
| Moul, JW | 1 |
| McLeod, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feedback Control of FSH Secretion in the Human Male[NCT00392457] | 175 participants (Anticipated) | Interventional | 1995-07-31 | Completed | |||
| Mechanisms of Hormonal Control of Spermatogenesis in Man[NCT02147964] | Phase 2 | 0 participants (Actual) | Interventional | 2019-06-30 | Withdrawn (stopped due to No funding was obtained for this study.) | ||
| Mechanisms of Control of the Intratesticular Hormonal Milieu in Man[NCT01215292] | Phase 1/Phase 2 | 46 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel (Tgel)+ Placebo | .87 |
| Acyline + Tgel + Ketoconazole 400mg | 0.5 |
| Acyline + Tgel + Ketoconazole 800mg | 0.12 |
| Acyline & TGel & Dutasteride 2.5mg | 1.7 |
| Acyline & TGel & Anastrazole 1mg | 3.6 |
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel (Tgel)+ Placebo | 3.17 |
| Acyline & TGel & Ketoconazole 400 mg | 2.08 |
| Acyline & TGel & Ketoconazole 800 mg | 1.46 |
| Acyline & TGel & Dutasteride | 0.12 |
| Acyline & TGel & Anastrazole | 3.63 |
(NCT01215292)
Timeframe: 10 days
| Intervention | ng/mL (Median) |
|---|---|
| Acyline + Testosterone Gel + Placebo | 14 |
| Acyline + Tgel + Ketoconazole 400mg | 3.7 |
| Acyline + Tgel + Ketoconazole 800mg | 1.7 |
| Acyline & TGel & Dutasteride 2.5mg | 18.4 |
| Acyline & TGel & Anastrazole 1mg | 24.0 |
1 review available for ketoconazole and Erectile Dysfunction
| Article | Year |
|---|---|
Drug-induced sexual dysfunction and infertility.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzothiadiazines; Child; Cimetidine; | 1984 |
1 trial available for ketoconazole and Erectile Dysfunction
| Article | Year |
|---|---|
Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects.
Topics: Access to Information; Administration, Oral; Adult; Asian People; Cross-Over Studies; Dose-Response | 2010 |
3 other studies available for ketoconazole and Erectile Dysfunction
| Article | Year |
|---|---|
Androgen blockade for the treatment of high-flow priapism.
Topics: Adult; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Erectile Dysfunct | 2010 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
High-dose ketoconazole therapy and adrenal and testicular function in humans.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Erectile Dysfunction; Gynecomastia; Humans; Hydr | 1984 |
Candida albicans corpora abscess following penile prosthesis placement.
Topics: Abscess; Amphotericin B; Candidiasis; Combined Modality Therapy; Drug Therapy, Combination; Erectile | 1988 |