ketoconazole has been researched along with Endophthalmitis in 17 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole is a weakly dibasic synthetic imidazole with a broad spectrum of antifungal activity." | 1.27 | Experimental intravitreal ketoconazole in DMSO. ( Banihashemi, AR; Yoshizumi, MO, 1988) |
| "Ketoconazole penetration was average in the aqueous humour, significant in tears and poor in the vitreous." | 1.27 | Experimental study of the intra-ocular penetration of ketoconazole in rabbits. ( Arne, JL; Bec, P; Bessieres, MH; Linas, MD; Malecaze, F; Mathis, A; Recco, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, DB | 2 |
| Green, MT | 1 |
| Osato, MS | 1 |
| Broberg, PH | 1 |
| Gentry, LO | 1 |
| Carney, MD | 1 |
| Tabassian, A | 1 |
| Guerry, RK | 1 |
| Gumbo, T | 1 |
| Mkanganwi, N | 1 |
| Robertson, VJ | 1 |
| Masvaire, P | 1 |
| Schulman, JA | 1 |
| Peyman, GA | 1 |
| Dietlein, J | 1 |
| Fiscella, R | 1 |
| Brod, RD | 1 |
| Flynn, HW | 1 |
| Clarkson, JG | 1 |
| Pflugfelder, SC | 1 |
| Culbertson, WW | 1 |
| Miller, D | 1 |
| Savani, DV | 1 |
| Perfect, JR | 1 |
| Cobo, LM | 1 |
| Durack, DT | 1 |
| Yoshizumi, MO | 1 |
| Banihashemi, AR | 1 |
| Caya, JG | 1 |
| Farmer, SG | 1 |
| Williams, GA | 1 |
| Franson, TR | 1 |
| Komorowski, RA | 1 |
| Kies, JC | 1 |
| Goodman, DF | 1 |
| Stern, WH | 1 |
| O'Day, DM | 1 |
| Head, WS | 1 |
| Robinson, RD | 1 |
| Barrie, T | 2 |
| Levin, PS | 1 |
| Beebe, WE | 1 |
| Abbott, RL | 1 |
| Malecaze, F | 1 |
| Linas, MD | 1 |
| Mathis, A | 1 |
| Arne, JL | 1 |
| Recco, P | 1 |
| Bessieres, MH | 1 |
| Bec, P | 1 |
| Weiss, JL | 1 |
| Parker, WT | 1 |
| Servant, JB | 1 |
| Dutton, GN | 1 |
| Ong-Tone, L | 1 |
| Davey, C | 1 |
17 other studies available for ketoconazole and Endophthalmitis
| Article | Year |
|---|---|
Chemotherapy of experimental endogenous Candida albicans endophthalmitis.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Disease Models, Animal; Drug Therapy, Combi | 1980 |
Endogenous Candida albicans endophthalmitis in the rabbit. Chemotherapy for systemic effect.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Endophthalmitis; Imidazoles; Injections, In | 1981 |
Pseudo-Allescheria boydii endophthalmitis.
Topics: Antifungal Agents; Child; Endophthalmitis; Eye Injuries; Humans; Ketoconazole; Male; Mycetoma; Pseud | 1996 |
Case report. Nattrassia mangiferae endophthalmitis.
Topics: Endophthalmitis; Humans; Ketoconazole; Male; Middle Aged; Mitosporic Fungi | 2002 |
Ocular toxicity of experimental intravitreal itraconazole.
Topics: Animals; Antifungal Agents; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Electroretinograph | 1991 |
Endogenous Candida endophthalmitis. Management without intravenous amphotericin B.
Topics: Adult; Aged; Amphotericin B; Candida; Candida albicans; Candidiasis; Endophthalmitis; Eye Infections | 1990 |
Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Endophthalmitis; Eye; Fluconazole; Itraco | 1987 |
Experimental intravitreal ketoconazole in DMSO.
Topics: Administration, Topical; Animals; Dimethyl Sulfoxide; Electroretinography; Endophthalmitis; Ketocona | 1988 |
Bilateral Pseudallescheria boydii endophthalmitis in an immunocompromised patient.
Topics: Amphotericin B; Ascomycota; Drug Resistance, Microbial; Endophthalmitis; Humans; Immune Tolerance; K | 1988 |
Oral ketoconazole and intraocular amphotericin B for treatment of postoperative Candida parapsilosis endophthalmitis.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amphotericin B; Candidiasis; Cataract Extraction; Dru | 1987 |
An outbreak of Candida parapsilosis endophthalmitis: analysis of strains by enzyme profile and antifungal susceptibility.
Topics: Amphotericin B; Candida; Candidiasis; Disease Outbreaks; Drug Contamination; Endophthalmitis; Flucyt | 1987 |
The place of elective vitrectomy in the management of patients with Candida endophthalmitis.
Topics: Amphotericin B; Candidiasis; Endophthalmitis; Female; Flucytosine; Follow-Up Studies; Humans; Ketoco | 1987 |
Successful treatment of Paecilomyces lilacinus endophthalmitis following cataract extraction with intraocular lens implantation.
Topics: Aged; Antifungal Agents; Cataract Extraction; Combined Modality Therapy; Endophthalmitis; Female; Hu | 1987 |
Experimental study of the intra-ocular penetration of ketoconazole in rabbits.
Topics: Animals; Aqueous Humor; Candidiasis; Endophthalmitis; Eye; Female; Ketoconazole; Male; Rabbits; Tear | 1987 |
Candida albicans endophthalmitis following penetrating keratoplasty.
Topics: Administration, Oral; Candidiasis; Corneal Transplantation; Endophthalmitis; Humans; Ketoconazole; M | 1987 |
Candidal endophthalmitis in Glaswegian heroin addicts: report of an epidemic.
Topics: Adolescent; Adult; Amphotericin B; Candidiasis; Disease Outbreaks; Endophthalmitis; Female; Fundus O | 1985 |
[Treatment Candida albicans endophthalmitis with ketoconazole].
Topics: Amphotericin B; Candidiasis; Endophthalmitis; Flucytosine; Humans; Ketoconazole | 1985 |