ketoconazole has been researched along with Endocrine System Diseases in 12 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term results of initial ketoconazole treatment were evaluated in 13 patients with chronic mucocutaneous candidiasis followed up for 3 years." | 9.06 | Ketoconazole treatment of 13 patients with chronic mucocutaneous candidiasis. A prospective 3-year trial. ( Mobacken, H; Moberg, S, 1986) |
| "In a multicenter prospective randomized trial, the efficacy and toxicity of low-dose (400 mg/d) and high-dose (800 mg/d) oral ketoconazole were compared in 80 patients with blastomycosis and in 54 with histoplasmosis." | 9.05 | Treatment of blastomycosis and histoplasmosis with ketoconazole. Results of a prospective randomized clinical trial. National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( , 1985) |
| " Because ketoconazole has in-vitro activity against Blastomyces dermatitidis, we administered this agent in a dosage of 400 mg/d to 46 patients with blastomycosis, with 43 patients receiving at least 1 month of therapy." | 5.27 | Ketoconazole therapy for endemic blastomycosis. ( Abernathy, RS; Bradsher, RW; Rice, DC, 1985) |
| "Long-term results of initial ketoconazole treatment were evaluated in 13 patients with chronic mucocutaneous candidiasis followed up for 3 years." | 5.06 | Ketoconazole treatment of 13 patients with chronic mucocutaneous candidiasis. A prospective 3-year trial. ( Mobacken, H; Moberg, S, 1986) |
| "In a multicenter prospective randomized trial, the efficacy and toxicity of low-dose (400 mg/d) and high-dose (800 mg/d) oral ketoconazole were compared in 80 patients with blastomycosis and in 54 with histoplasmosis." | 5.05 | Treatment of blastomycosis and histoplasmosis with ketoconazole. Results of a prospective randomized clinical trial. National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( , 1985) |
| "Ketoconazole was effective in controlling symptoms of candidiasis in most patients." | 1.28 | Chronic mucocutaneous candidiasis in childhood and complications of non-Candida infection: a report of the Pediatric Immunodeficiency Collaborative Study Group. ( Herrod, HG, 1990) |
| " Because ketoconazole has in-vitro activity against Blastomyces dermatitidis, we administered this agent in a dosage of 400 mg/d to 46 patients with blastomycosis, with 43 patients receiving at least 1 month of therapy." | 1.27 | Ketoconazole therapy for endemic blastomycosis. ( Abernathy, RS; Bradsher, RW; Rice, DC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Appleboom, TM | 1 |
| Flowers, FP | 1 |
| Graybill, JR | 1 |
| Miossec, P | 1 |
| Archambeaud-Mouveroux, F | 1 |
| Teissier, MP | 1 |
| Herrod, HG | 1 |
| Feuillan, P | 1 |
| Poth, M | 1 |
| Reilly, W | 1 |
| Bright, G | 1 |
| Loriaux, DL | 1 |
| Chrousos, GP | 1 |
| Mobacken, H | 1 |
| Moberg, S | 1 |
| Mangas-Rojas, A | 1 |
| Barba Chacón, A | 1 |
| García Rojas, JF | 1 |
| Zamora-Madaria, E | 1 |
| Sonino, N | 2 |
| Leal-Cerro, A | 1 |
| García-Luna, PP | 1 |
| Bradsher, RW | 1 |
| Rice, DC | 1 |
| Abernathy, RS | 1 |
2 reviews available for ketoconazole and Endocrine System Diseases
| Article | Year |
|---|---|
[Inhibition of steroidogenesis by ketoconazole. Therapeutic uses].
Topics: Adrenal Glands; Aldehyde-Lyases; Androgen Antagonists; Animals; Cytochrome P-450 Enzyme System; Endo | 1997 |
The endocrine effects of ketoconazole.
Topics: Animals; Breast Neoplasms; Cushing Syndrome; Endocrine System Diseases; Female; Hirsutism; Humans; K | 1986 |
2 trials available for ketoconazole and Endocrine System Diseases
| Article | Year |
|---|---|
Treatment of blastomycosis and histoplasmosis with ketoconazole. Results of a prospective randomized clinical trial. National Institute of Allergy and Infectious Diseases Mycoses Study Group.
Topics: Adult; Aged; Blastomycosis; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, D | 1985 |
Ketoconazole treatment of 13 patients with chronic mucocutaneous candidiasis. A prospective 3-year trial.
Topics: Administration, Oral; Adolescent; Adult; Candidiasis; Candidiasis, Chronic Mucocutaneous; Child; Chi | 1986 |
8 other studies available for ketoconazole and Endocrine System Diseases
| Article | Year |
|---|---|
Ketoconazole in the treatment of chronic mucocutaneous candidiasis secondary to autoimmune polyendocrinopathy-candidiasis syndrome.
Topics: Adolescent; Antifungal Agents; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Mucocutaneous; | 1982 |
Potential and problems with ketoconazole.
Topics: Antifungal Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Coccidioidomycosis; Endocrin | 1983 |
Chronic mucocutaneous candidiasis in childhood and complications of non-Candida infection: a report of the Pediatric Immunodeficiency Collaborative Study Group.
Topics: Adolescent; Amphotericin B; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Mucocutaneous; Ch | 1990 |
Ketoconazole treatment of type 1 autoimmune polyglandular syndrome: effects on pituitary-adrenal axis.
Topics: Adrenocorticotropic Hormone; Autoimmune Diseases; Candidiasis, Oral; Child; Corticotropin-Releasing | 1986 |
[Effect of ketoconazole on the serum level of total testosterone, free testosterone and estradiol in normal subjects].
Topics: Adult; Dose-Response Relationship, Drug; Endocrine System Diseases; Estradiol; Female; Humans; Ketoc | 1988 |
Current trends in the endocrine use of ketoconazole.
Topics: Chemical Phenomena; Chemistry; Cushing Syndrome; Endocrine System Diseases; Female; Hirsutism; Human | 1988 |
[Ketoconazole: new perspectives in endocrinology].
Topics: Endocrine System Diseases; Humans; Ketoconazole | 1986 |
Ketoconazole therapy for endemic blastomycosis.
Topics: Adult; Aged; Blastomycosis; Endocrine System Diseases; Female; Humans; Ketoconazole; Lung Diseases, | 1985 |