ketoconazole has been researched along with Endocarditis in 8 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 7.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " Review of these five cases and 31 additional relapsing cases from the literature indicates that fungal endocarditis or endarteritis without surgical treatment, underlying lymphoreticular neoplasm, and amphotericin B dosage of less than 2 g appear to be associated with relapse of PDH." | 5.26 | Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis. ( Alford, RH; Bradsher, RW; Hawkins, SS; Spickard, WA, 1982) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 5.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 3.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " The proper duration and dosage and the combination of antifungal drugs have not been clearly defined." | 2.38 | [Primary Aspergillus endocarditis. Apropos of a case and review of the international literature]. ( Cajot, MA; Gosselin, B; Goullard, L; Koussa, A; Marquette, F; Pol, A; Roux, JP; Soots, G; Warembourg, H, 1992) |
| " Review of these five cases and 31 additional relapsing cases from the literature indicates that fungal endocarditis or endarteritis without surgical treatment, underlying lymphoreticular neoplasm, and amphotericin B dosage of less than 2 g appear to be associated with relapse of PDH." | 1.26 | Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis. ( Alford, RH; Bradsher, RW; Hawkins, SS; Spickard, WA, 1982) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 1.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samelson, LE | 1 |
| Lerner, SA | 1 |
| Resnekov, L | 1 |
| Anagnostopoulos, C | 1 |
| Bradsher, RW | 1 |
| Alford, RH | 1 |
| Hawkins, SS | 1 |
| Spickard, WA | 1 |
| Drouhet, E | 1 |
| Guilmet, D | 1 |
| Kouvalchouk, JF | 1 |
| Chapman, A | 1 |
| Ziza, JM | 1 |
| Laudet, J | 1 |
| Brodaty, D | 1 |
| Thomas, D | 1 |
| Mogahed, A | 1 |
| Leclerc, JP | 1 |
| Grosgogeat, Y | 1 |
| Roux, JP | 1 |
| Koussa, A | 1 |
| Cajot, MA | 1 |
| Marquette, F | 1 |
| Goullard, L | 1 |
| Gosselin, B | 1 |
| Pol, A | 1 |
| Warembourg, H | 1 |
| Soots, G | 1 |
| Longman, LP | 1 |
| Martin, MV | 1 |
| Pruett, TL | 1 |
| Rotstein, OD | 1 |
| Anderson, RW | 1 |
| Simmons, RL | 1 |
| Vartian, CV | 1 |
| Shlaes, DM | 1 |
| Padhye, AA | 1 |
| Ajello, L | 1 |
1 review available for ketoconazole and Endocarditis
| Article | Year |
|---|---|
[Primary Aspergillus endocarditis. Apropos of a case and review of the international literature].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Combined Modality Therapy; | 1992 |
7 other studies available for ketoconazole and Endocarditis
| Article | Year |
|---|---|
Relapse of Candida parapsilosis endocarditis after long-term suppression with flucytosin: retreatment with valve replacement and ketoconazole.
Topics: Adult; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Endocarditis; Female; Flucy | 1980 |
Conditions associated with relapse of amphotericin B-treated disseminated histoplasmosis.
Topics: Aged; Amphotericin B; Antifungal Agents; Endocarditis; Histoplasmosis; Humans; Imidazoles; Ketoconaz | 1982 |
[First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B].
Topics: Adult; Amphotericin B; Antifungal Agents; Endocarditis; Female; Heart Valve Prosthesis; Humans; Imid | 1982 |
Prosthetic valve endocarditis caused by Trichosporon cutaneum.
Topics: Aortic Valve; Basidiomycota; Endocarditis; Female; Heart Valve Prosthesis; Humans; Ketoconazole; Mid | 1984 |
A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Endocarditis; Fluc | 1987 |
Tricuspid valve Candida endocarditis. Successful treatment with valve-sparing debridement and antifungal chemotherapy in a multiorgan transplant recipient.
Topics: Adult; Amphotericin B; Antifungal Agents; Candidiasis; Combined Modality Therapy; Debridement; Endoc | 1986 |
Wangiella dermatitidis endocarditis in an intravenous drug user.
Topics: Adult; Amphotericin B; Aortic Valve; Drug Therapy, Combination; Endocarditis; Heart Valve Diseases; | 1985 |