ketoconazole has been researched along with Ectopic ACTH Syndrome in 20 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The property of ketoconazole to inhibit adrenal biosynthesis of cortisol was used in a clinical study of 14 patients with Cushing's syndrome (pituitary-dependent Cushing's disease, n = 10; adrenocortical adenoma, n = 2; adrenocortical carcinoma, n = 1; ectopic ACTH syndrome, n = 1)." | 9.06 | Different therapeutic efficacy of ketoconazole in patients with Cushing's syndrome. ( Doerr, HG; Engelhardt, D; Jacob, K, 1989) |
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 7.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 7.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "A case is herein reported of pneumocystis carinii pneumonia in a 60-year-old female patient with ectopic production of ACTH at a position 2 cm superior to her right clavicle, revealed in an octreotide scan." | 5.31 | Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole. ( Choi, WH; Choi, YY; Jeon, SC; Kim, DS; Kim, TW; Park, SK; Ryu, JS, 2000) |
| "The property of ketoconazole to inhibit adrenal biosynthesis of cortisol was used in a clinical study of 14 patients with Cushing's syndrome (pituitary-dependent Cushing's disease, n = 10; adrenocortical adenoma, n = 2; adrenocortical carcinoma, n = 1; ectopic ACTH syndrome, n = 1)." | 5.06 | Different therapeutic efficacy of ketoconazole in patients with Cushing's syndrome. ( Doerr, HG; Engelhardt, D; Jacob, K, 1989) |
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 3.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 3.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "Cushing syndrome is a rare endocrine disorder." | 1.91 | An exceptionally rare case of Cushing's syndrome caused by ectopic ACTH syndrome due to olfactory neuroblastoma in childhood. ( Gülten, G; Özhan, B; Yalçın, N; Yıldırım Çakar, D, 2023) |
| "The case of a patient with recurrent esthesioneuroblastoma complicated by ectopic adrenocorticotropic hormone production is presented, including the workup and management of this uncommon complication of an uncommon disease." | 1.36 | Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital. ( Benito, M; Mintzer, DM; Nagamine, M; Newman, J; Zheng, S, 2010) |
| "A case is herein reported of pneumocystis carinii pneumonia in a 60-year-old female patient with ectopic production of ACTH at a position 2 cm superior to her right clavicle, revealed in an octreotide scan." | 1.31 | Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole. ( Choi, WH; Choi, YY; Jeon, SC; Kim, DS; Kim, TW; Park, SK; Ryu, JS, 2000) |
| "Treatment with ketoconazole (KCZ) resulted in significant suppression of serum cortisol levels." | 1.28 | The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome. ( Brigham, B; Hoffman, DM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Özhan, B | 1 |
| Yıldırım Çakar, D | 1 |
| Gülten, G | 1 |
| Yalçın, N | 1 |
| Biagetti, B | 1 |
| Simó-Servat, O | 1 |
| Ortiz-Z, A | 1 |
| Iglesias, C | 1 |
| Mesa, J | 1 |
| Simó-Servat, A | 1 |
| Peiró, I | 1 |
| Villabona, C | 1 |
| Ilie, MD | 1 |
| Raverot, V | 1 |
| Tronc, F | 1 |
| Vasiljevic, A | 1 |
| Borson-Chazot, F | 1 |
| Raverot, G | 1 |
| Corcuff, JB | 2 |
| Young, J | 1 |
| Masquefa-Giraud, P | 1 |
| Chanson, P | 1 |
| Baudin, E | 1 |
| Tabarin, A | 2 |
| Paun, DL | 1 |
| Vija, L | 1 |
| Stan, E | 1 |
| Banica, A | 1 |
| Bobeica, E | 1 |
| Terzea, D | 1 |
| Poiana, C | 1 |
| Badiu, C | 1 |
| Paun, S | 1 |
| George, JC | 1 |
| Vedamurthy, D | 1 |
| Bermudez, M | 1 |
| Kennedy, JW | 1 |
| Mintzer, DM | 1 |
| Zheng, S | 1 |
| Nagamine, M | 1 |
| Newman, J | 1 |
| Benito, M | 1 |
| La Rosa, S | 1 |
| Marando, A | 1 |
| Ghezzi, F | 1 |
| Colombo, P | 1 |
| Finzi, G | 1 |
| Capella, C | 1 |
| Winquist, EW | 1 |
| Laskey, J | 2 |
| Crump, M | 1 |
| Khamsi, F | 2 |
| Shepherd, FA | 2 |
| Singh, CP | 1 |
| Kumar, A | 1 |
| Agarwal, AK | 1 |
| Gupta, H | 1 |
| Gupta, A | 1 |
| Kim, DS | 1 |
| Park, SK | 1 |
| Choi, WH | 1 |
| Kim, TW | 1 |
| Choi, YY | 1 |
| Jeon, SC | 1 |
| Ryu, JS | 1 |
| Rickman, T | 1 |
| Garmany, R | 1 |
| Doherty, T | 1 |
| Benson, D | 1 |
| Okusa, MD | 1 |
| Evans, WK | 1 |
| Goss, PE | 1 |
| Johansen, E | 1 |
| Pérez Gracia, A | 1 |
| Ramírez, L | 1 |
| Herrero, V | 1 |
| Espinosa, J | 1 |
| Kornely, E | 1 |
| Schlaghecke, R | 1 |
| Horster, FA | 1 |
| Hoffman, DM | 1 |
| Brigham, B | 1 |
| Navarranne, A | 1 |
| Guérin, J | 1 |
| Parneix, M | 1 |
| Roger, P | 1 |
| Engelhardt, D | 2 |
| Jacob, K | 1 |
| Doerr, HG | 1 |
| Weber, MM | 1 |
| Luppa, P | 1 |
1 trial available for ketoconazole and Ectopic ACTH Syndrome
| Article | Year |
|---|---|
Different therapeutic efficacy of ketoconazole in patients with Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Cushi | 1989 |
19 other studies available for ketoconazole and Ectopic ACTH Syndrome
| Article | Year |
|---|---|
An exceptionally rare case of Cushing's syndrome caused by ectopic ACTH syndrome due to olfactory neuroblastoma in childhood.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Child; Child, Preschool; Cushing Syndrome; Esth | 2023 |
Ectopic Cushing's syndrome: Paradoxical effect of somatostatin analogs.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adrenocorticotropic | 2017 |
Corticotropin secreting pancreatic neuroendocrine tumour, a therapeutic management challenge. A presentation of 2 cases.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Chromogranins; Combined Modality Therapy; Embol | 2019 |
Cabergoline in severe ectopic or occult Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cabergoline; Carcinoid Tumor; Cushing Syndrome; Dopamine Agonis | 2019 |
Rapid control of severe neoplastic hypercortisolism with metyrapone and ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Cushing Synd | 2015 |
Cushing syndrome secondary to ectopic adrenocorticotropic hormone secretion from a Meckel diverticulum neuroendocrine tumor: case report.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing | 2015 |
Quiz Page October 2016: Severe Hypokalemia, Metabolic Alkalosis, and Malignancy.
Topics: ACTH Syndrome, Ectopic; Alkalosis; Amiloride; Cytochrome P-450 CYP3A Inhibitors; Diabetes Insipidus; | 2016 |
Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antifungal Agents; An | 2010 |
Cushing's syndrome due to a pancreatic neuroendocrine tumor metastatic to the ovaries: a clinicopathological description of a case.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoma, Neuroendocrine; Cushing Syndrome; Fatal Outcome; Female; H | 2011 |
Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Carcinoma, Small Cell; Caus | 1995 |
Cushing's syndrome induced by occult ectopic acth secretion.
Topics: ACTH Syndrome, Ectopic; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Ketoconazole; Neopl | 1995 |
Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Disseminated Intravascular Coagulation; Escheri | 2000 |
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma.
Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Adrenocorticotropic Hormone; Aged; Alkalosis; Comorbidity; C | 2001 |
Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Smal | 1992 |
[Treatment with ketoconazole of Cushing's syndrome due to ectopic secretion of ACTH].
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Humans; Ketoconazole | 1992 |
Palliative therapy of an ectopic Cushing's syndrome due to a metastatic carcinoid tumor.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoid Tumor; Combined Modality Therapy; Cushing Syndrome; Dose-Re | 1991 |
The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome.
Topics: ACTH Syndrome, Ectopic; Carcinoma, Small Cell; Female; Humans; Ketoconazole; Lung Neoplasms; Middle | 1991 |
Use of ketoconazole in the treatment of Cushing's disease and ectopic ACTH syndrome.
Topics: ACTH Syndrome, Ectopic; Adult; Cushing Syndrome; Diagnosis, Differential; Female; Humans; Hydrocorti | 1991 |
Inhibition of human adrenal androgen secretion by ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Cushing Syndrome; Female | 1989 |