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ketoconazole and Disseminated Intravascular Coagulation

ketoconazole has been researched along with Disseminated Intravascular Coagulation in 6 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

Research Excerpts

ExcerptRelevanceReference
"We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma."7.67Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989)
"Biological investigations revealed a disseminated intravascular coagulation (DIC)."6.38[Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative]. ( Balin, C; Fleyfel, M; Leroy, B; Marecaux, O; Plouvier, F; Scherpereel, P, 1991)
"A case is herein reported of pneumocystis carinii pneumonia in a 60-year-old female patient with ectopic production of ACTH at a position 2 cm superior to her right clavicle, revealed in an octreotide scan."5.31Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole. ( Choi, WH; Choi, YY; Jeon, SC; Kim, DS; Kim, TW; Park, SK; Ryu, JS, 2000)
"A patient with spontaneous bleeding from disseminated intravascular coagulation was treated with 400 mg."5.27The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer. ( Lowe, FC; Somers, WJ, 1987)
"We report the use of ketoconazole to control disseminated intravascular coagulation due to prostatic carcinoma."3.67Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma. ( Bhadoria, DP; Malhotra, KK; Mehta, S; Mittal, D; Mukhopadhyay, DK; Rao, YV, 1989)
"For metastatic prostatic cancer presenting with an emergency oncologic condition, the treatment of choice is surgical orchiectomy, but surgery may not be possible in the presence of severe DIC."2.41Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review. ( Amornpichetkul, K; Chakrapee-Sirisuk, S; Sangruchi, T; Sinlarat, P; Srimuninnimit, V; Visudhiphan, S, 2001)
"Biological investigations revealed a disseminated intravascular coagulation (DIC)."2.38[Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative]. ( Balin, C; Fleyfel, M; Leroy, B; Marecaux, O; Plouvier, F; Scherpereel, P, 1991)
"A case is herein reported of pneumocystis carinii pneumonia in a 60-year-old female patient with ectopic production of ACTH at a position 2 cm superior to her right clavicle, revealed in an octreotide scan."1.31Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole. ( Choi, WH; Choi, YY; Jeon, SC; Kim, DS; Kim, TW; Park, SK; Ryu, JS, 2000)
"A patient with spontaneous bleeding from disseminated intravascular coagulation was treated with 400 mg."1.27The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer. ( Lowe, FC; Somers, WJ, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, DS1
Park, SK1
Choi, WH1
Kim, TW1
Choi, YY1
Jeon, SC1
Ryu, JS1
Chakrapee-Sirisuk, S1
Amornpichetkul, K1
Visudhiphan, S1
Sangruchi, T1
Srimuninnimit, V1
Sinlarat, P1
Fleyfel, M1
Leroy, B1
Plouvier, F1
Balin, C1
Marecaux, O1
Scherpereel, P1
Bhadoria, DP1
Mukhopadhyay, DK1
Mehta, S1
Mittal, D1
Rao, YV1
Malhotra, KK1
Lowe, FC1
Somers, WJ1
Litt, MR1
Bell, WR1
Lepor, HA1

Reviews

2 reviews available for ketoconazole and Disseminated Intravascular Coagulation

ArticleYear
Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:10

    Topics: Antifungal Agents; Antineoplastic Agents, Hormonal; Disseminated Intravascular Coagulation; Drug The

2001
[Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative].
    Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Biopsy, Needle; Blood Coagulation Tests; Diethylstilbestrol;

1991

Other Studies

4 other studies available for ketoconazole and Disseminated Intravascular Coagulation

ArticleYear
Pneumocystis carinii pneumonia associated with a rapid reduction of cortisol level in a patient with ectopic ACTH syndrome treated by octreotide and ketoconazole.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2000, Volume: 108, Issue:2

    Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Disseminated Intravascular Coagulation; Escheri

2000
Emergency treatment with ketoconazole in disseminated intravascular coagulation due to metastatic prostatic carcinoma.
    The Journal of the Association of Physicians of India, 1989, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Disseminated Intravascular Coagulation; Emergencies; Humans; K

1989
The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer.
    The Journal of urology, 1987, Volume: 137, Issue:5

    Topics: Adenocarcinoma; Aged; Disseminated Intravascular Coagulation; Emergencies; Humans; Ketoconazole; Mal

1987
Disseminated intravascular coagulation in prostatic carcinoma reversed by ketoconazole.
    JAMA, 1987, Sep-11, Volume: 258, Issue:10

    Topics: Aged; Aged, 80 and over; Disseminated Intravascular Coagulation; Humans; Ketoconazole; Male; Prostat

1987