ketoconazole has been researched along with Depression, Involutional in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Part 1 was an open-label pharmacokinetic assessment of a single 5-mg vilazodone dose with or without ketoconazole." | 2.79 | Influence of CYP3A4 induction/inhibition on the pharmacokinetics of vilazodone in healthy subjects. ( Boinpally, R; Gad, N; Gupta, S; Periclou, A, 2014) |
| "Ketoconazole was generally well tolerated with no occurrence of significant side effects or laboratory abnormalities." | 2.69 | Antiglucocorticoid treatment of depression: double-blind ketoconazole. ( Canick, J; Chan, T; Johnson, R; Manfredi, F; Raum, W; Reus, VI; Wolkowitz, OM, 1999) |
| "Major depressive disorder affects a substantial percentage of the U." | 2.45 | Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus? ( Coleman, VH; Kling, MA; Schulkin, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boinpally, R | 1 |
| Gad, N | 1 |
| Gupta, S | 1 |
| Periclou, A | 1 |
| Kling, MA | 1 |
| Coleman, VH | 1 |
| Schulkin, J | 1 |
| Paslakis, G | 1 |
| Lecei, O | 1 |
| Stalla, GK | 1 |
| Landgraf, R | 1 |
| Uhr, M | 1 |
| Hamann, B | 1 |
| Luppa, P | 1 |
| Gilles, M | 1 |
| Heuser, I | 1 |
| Deuschle, M | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Chan, T | 1 |
| Manfredi, F | 1 |
| Raum, W | 1 |
| Johnson, R | 1 |
| Canick, J | 1 |
| Bech, P | 1 |
| Raabaek Olsen, L | 1 |
| Jarløv, N | 1 |
| Hammer, M | 1 |
| Schütze, T | 1 |
| Breum, L | 1 |
1 review available for ketoconazole and Depression, Involutional
| Article | Year |
|---|---|
Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?
Topics: Adrenal Glands; Aminoglutethimide; Anti-Inflammatory Agents; Corticotropin-Releasing Hormone; Depres | 2009 |
3 trials available for ketoconazole and Depression, Involutional
| Article | Year |
|---|---|
Influence of CYP3A4 induction/inhibition on the pharmacokinetics of vilazodone in healthy subjects.
Topics: Adolescent; Adult; Carbamazepine; Cross-Over Studies; Cytochrome P-450 CYP3A Inducers; Cytochrome P- | 2014 |
The effect of treatment with ketoconazole on central CRH systems of depressed patients.
Topics: 14-alpha Demethylase Inhibitors; Aged; Aged, 80 and over; Arginine Vasopressin; Corticotropin-Releas | 2011 |
Antiglucocorticoid treatment of depression: double-blind ketoconazole.
Topics: Adult; Depressive Disorder, Major; Double-Blind Method; Female; Glucocorticoids; Humans; Hydrocortis | 1999 |
1 other study available for ketoconazole and Depression, Involutional
| Article | Year |
|---|---|
A case of sequential anti-stress medication in a patient with major depression resistant to amine-reuptake inhibitors.
Topics: Amines; Antidepressive Agents; Anxiety Disorders; Dehydroepiandrosterone; Depressive Disorder, Major | 1999 |