ketoconazole has been researched along with Delayed Hypersensitivity in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo, subchronic intraperitoneal dosing with 40 mg/kg ketoconazole or itraconazole to mice had no effect on the antibody response to SRBC as measured by the number of splenic IgM and IgG plaque-forming cells and did not significantly affect the DTH response to oxazolone." | 1.28 | Lack of immunosuppression by ketoconazole and itraconazole. ( Aerts, F; Cools, M; Van Wauwe, J, 1992) |
| "Ketoconazole alone was not immunosuppressive." | 1.27 | Pharmacodynamics of cyclosporine-ketoconazole interaction in mice. Combined therapy potentiates cyclosporine immunosuppression and toxicity. ( Anderson, JE; Blaschke, TF; Morris, RE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoyos, GL | 1 |
| McEwen, JG | 1 |
| Brummer, E | 1 |
| Castañeda, E | 1 |
| Restrepo, A | 1 |
| Stevens, DA | 1 |
| Cools, M | 1 |
| Aerts, F | 1 |
| Van Wauwe, J | 1 |
| Ulrich, B | 1 |
| Frey, FJ | 1 |
| Speck, RF | 1 |
| Frey, BM | 1 |
| Anderson, JE | 2 |
| Morris, RE | 2 |
| Blaschke, TF | 2 |
5 other studies available for ketoconazole and Delayed Hypersensitivity
| Article | Year |
|---|---|
Chronic murine paracoccidioidomycosis: effect of ketoconazole on clearance of Paracoccidioides brasiliensis and immune response.
Topics: Animals; Antibodies, Fungal; Chronic Disease; Disease Models, Animal; Fungi; Hypersensitivity, Delay | 1984 |
Lack of immunosuppression by ketoconazole and itraconazole.
Topics: Animals; Antibody Formation; Antifungal Agents; DNA; Female; Hypersensitivity, Delayed; Immunosuppre | 1992 |
Pharmacokinetics/pharmacodynamics of ketoconazole-prednisolone interaction.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Interactions; Hemocyanins; Hypersensitivity, Del | 1992 |
Ketoconazole potentiates cyclosporine immunosuppression and toxicity in mice.
Topics: Animals; Cyclosporins; Dose-Response Relationship, Drug; Drug Synergism; Hypersensitivity, Delayed; | 1987 |
Pharmacodynamics of cyclosporine-ketoconazole interaction in mice. Combined therapy potentiates cyclosporine immunosuppression and toxicity.
Topics: Animals; Cyclosporins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hypersensitivity | 1987 |