ketoconazole has been researched along with Complication, Postoperative in 32 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have reported the first case of successful treatment of disseminated histoplasmosis in a renal allograft recipient using a short course (14 days) of amphotericin B in combination with prolonged therapy (161 days) with ketoconazole." | 7.67 | Combined ketoconazole and amphotericin B treatment of acute disseminated histoplasmosis in a renal allograft recipient. ( Goetz, MB; Jones, JM, 1985) |
| "The bioavailability of orally administrated cyclosporine A (CsA) is poor and variable in liver transplantation recipients." | 5.35 | Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. ( Ikemura, K; Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Urano, K, 2009) |
| "Ketoconazole was discontinued after 12 months of chronic therapy, but 2 weeks after discontinuation, blastomycosis recurred." | 5.28 | Successful treatment of systemic blastomycosis with high-dose ketoconazole in a renal transplant recipient. ( DeVeber, G; Hii, JH; Legault, L; Vas, SI, 1990) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 5.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| "The aim of this study was to evaluate HPA intervention with low-dose ethanol, morphine, or ketoconazole on the neuroendocrine-immune axis and development of postoperative pneumonia in long-term alcoholic patients." | 5.12 | Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics. ( Achterberg, E; Althoff, H; Bohm, B; Eggers, V; Hegenscheid, K; Kaisers, U; Klein, M; Lau, A; Marks, C; Miller, P; Paschen, C; Pfeiffer, S; Sander, M; Schoenfeld, H; Schroeder, T; Spies, C; Szabo, G; Volk, HD; von Dossow, V; Wernecke, KD; Ziemer, S, 2006) |
| "We have reported the first case of successful treatment of disseminated histoplasmosis in a renal allograft recipient using a short course (14 days) of amphotericin B in combination with prolonged therapy (161 days) with ketoconazole." | 3.67 | Combined ketoconazole and amphotericin B treatment of acute disseminated histoplasmosis in a renal allograft recipient. ( Goetz, MB; Jones, JM, 1985) |
| "Ketoconazole is a reliable method to prevent postoperative penile erection." | 2.68 | Ketoconazole for prevention of postoperative penile erection. ( Kaplan, GW; Stock, JA, 1995) |
| "Treatment of Cushing's disease poses interesting dilemmas in clinical practice." | 1.42 | Assessment of the outcomes of the treatment of Cushing's disease in the hospitals of Castilla-La Mancha. ( Aguirre, M; Alramadan, M; Huguet, I; Lamas, C; Quiroga, I; Silva, J; Vicente, A, 2015) |
| "The bioavailability of orally administrated cyclosporine A (CsA) is poor and variable in liver transplantation recipients." | 1.35 | Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. ( Ikemura, K; Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Urano, K, 2009) |
| "Ketoconazole was discontinued after 12 months of chronic therapy, but 2 weeks after discontinuation, blastomycosis recurred." | 1.28 | Successful treatment of systemic blastomycosis with high-dose ketoconazole in a renal transplant recipient. ( DeVeber, G; Hii, JH; Legault, L; Vas, SI, 1990) |
| "Cutaneous chromomycosis occurred in two renal transplant recipients from the south central United States." | 1.27 | Cutaneous chromomycosis in renal transplant recipients. Successful management in two cases. ( Gray, GF; Gregg, CR; Richie, RE; Wackym, PA, 1985) |
| " In some resistant or extremely severe fungal infections antifungal agents can be used in combinations for their synergistic effects, with subsequent reduction of dosage and potential side-effects." | 1.26 | [First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B]. ( Brodaty, D; Chapman, A; Drouhet, E; Guilmet, D; Kouvalchouk, JF; Laudet, J; Ziza, JM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (34.38) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huguet, I | 1 |
| Aguirre, M | 1 |
| Vicente, A | 1 |
| Alramadan, M | 1 |
| Quiroga, I | 1 |
| Silva, J | 1 |
| Lamas, C | 1 |
| Ikemura, K | 1 |
| Urano, K | 1 |
| Matsuda, H | 1 |
| Mizutani, H | 1 |
| Iwamoto, T | 1 |
| Okuda, M | 1 |
| Masmoudi, A | 1 |
| Ben Salah, H | 1 |
| Makni, F | 1 |
| Chikrouhou, F | 1 |
| Boudaya, S | 1 |
| Ayadi, A | 1 |
| Turki, H | 1 |
| Silva, V | 1 |
| Zepeda, G | 1 |
| Alvareda, D | 1 |
| Evans, KC | 1 |
| Peterson, AC | 2 |
| Ruiz, HE | 1 |
| Costabile, RA | 2 |
| Udgiri, NR | 1 |
| Mettu, SR | 1 |
| Spies, C | 1 |
| Eggers, V | 1 |
| Szabo, G | 1 |
| Lau, A | 1 |
| von Dossow, V | 1 |
| Schoenfeld, H | 1 |
| Althoff, H | 1 |
| Hegenscheid, K | 1 |
| Bohm, B | 1 |
| Schroeder, T | 1 |
| Pfeiffer, S | 1 |
| Ziemer, S | 1 |
| Paschen, C | 1 |
| Klein, M | 1 |
| Marks, C | 1 |
| Miller, P | 1 |
| Sander, M | 1 |
| Wernecke, KD | 1 |
| Achterberg, E | 1 |
| Kaisers, U | 1 |
| Volk, HD | 1 |
| Kanavi, MR | 1 |
| Foroutan, AR | 1 |
| Kamel, MR | 1 |
| Afsar, N | 1 |
| Javadi, MA | 1 |
| DeCastro, BJ | 1 |
| McMann, LP | 1 |
| Zazgornik, J | 1 |
| Kopsa, H | 1 |
| Schmidt, P | 1 |
| Marosi, L | 1 |
| Balcke, P | 1 |
| Drouhet, E | 1 |
| Guilmet, D | 1 |
| Kouvalchouk, JF | 1 |
| Chapman, A | 1 |
| Ziza, JM | 1 |
| Laudet, J | 1 |
| Brodaty, D | 1 |
| Stock, JA | 1 |
| Kaplan, GW | 1 |
| Savino, JA | 1 |
| Agarwal, N | 1 |
| Wry, P | 1 |
| Policastro, A | 1 |
| Cerabona, T | 1 |
| Austria, L | 1 |
| Ben Hamida, F | 1 |
| Achard, JM | 1 |
| Westeel, PF | 1 |
| Chandenier, J | 1 |
| Bouzernidj, M | 1 |
| Petit, J | 1 |
| Carme, B | 1 |
| Fournier, A | 1 |
| Berrouane, YF | 1 |
| Herwaldt, LA | 1 |
| Pfaller, MA | 1 |
| Finielz, P | 1 |
| Pavese, P | 1 |
| Brion, JP | 1 |
| Lebeau, B | 1 |
| Grillot, R | 1 |
| Ambroise-Thomas, P | 1 |
| Moreno, M | 1 |
| Latorre, A | 1 |
| Manzanares, C | 1 |
| Morales, E | 1 |
| Herrero, JC | 1 |
| Dominguez-Gil, B | 1 |
| Carreño, A | 1 |
| Cubas, A | 1 |
| Delgado, M | 1 |
| Andres, A | 1 |
| Morales, JM | 1 |
| Carlson, AN | 1 |
| Foulks, GN | 1 |
| Perfect, JR | 1 |
| Kim, JH | 1 |
| Masclans, JR | 1 |
| Pérez, A | 1 |
| Tenorio, L | 1 |
| Planas, M | 1 |
| Franco, A | 1 |
| Prados, MC | 1 |
| Perdiguero, M | 1 |
| Olivares, J | 1 |
| Kramer, MR | 1 |
| Denning, DW | 1 |
| Marshall, SE | 1 |
| Ross, DJ | 1 |
| Berry, G | 1 |
| Lewiston, NJ | 1 |
| Stevens, DA | 1 |
| Theodore, J | 1 |
| Hii, JH | 1 |
| Legault, L | 1 |
| DeVeber, G | 1 |
| Vas, SI | 1 |
| Faggian, G | 1 |
| Livi, U | 1 |
| Bortolotti, U | 1 |
| Mazzucco, A | 1 |
| Stellin, G | 1 |
| Chiominto, B | 1 |
| Vivani, MA | 1 |
| Gallucci, V | 1 |
| Slotman, GJ | 1 |
| Burchard, KW | 1 |
| D'Arezzo, A | 1 |
| Gann, DS | 1 |
| O'Day, DM | 2 |
| Head, WS | 2 |
| Robinson, RD | 2 |
| Levin, PS | 1 |
| Beebe, WE | 1 |
| Abbott, RL | 1 |
| Weiss, JL | 1 |
| Parker, WT | 1 |
| Granier, F | 1 |
| Kanitakis, J | 1 |
| Hermier, C | 1 |
| Zhu, YY | 1 |
| Thivolet, J | 1 |
| Wackym, PA | 1 |
| Gray, GF | 1 |
| Richie, RE | 1 |
| Gregg, CR | 1 |
| Goetz, MB | 1 |
| Jones, JM | 1 |
| Stern, WH | 1 |
| Freeman, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Double-Blind Trial for Prevention of Recurrent Ischemic Priapism in Men With Sickle Cell Disease: A Pilot Study[NCT05142254] | Phase 2 | 64 participants (Actual) | Interventional | 2022-04-01 | Active, not recruiting | ||
| AMBINEB: Clinical Trial to Evaluate Tolerance and Safety of Nebulized Liposomal Amphotericin B Ambisome for Prophylaxis of Invasive Pulmonary Aspergillosis in Patients With Acute Myeloid Leukemia and Allogeneic Haematopoietic Progenitor Cell Transplant (A[NCT00391014] | Phase 2 | 150 participants (Anticipated) | Interventional | 2006-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for ketoconazole and Complication, Postoperative
| Article | Year |
|---|---|
Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics.
Topics: Aged; Alcoholism; Antifungal Agents; APACHE; Comorbidity; Cushing Syndrome; Digestive System Neoplas | 2006 |
Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial.
Topics: Administration, Oral; Adult; Double-Blind Method; Humans; Ketoconazole; Male; Penile Erection; Penis | 2008 |
Ketoconazole for prevention of postoperative penile erection.
Topics: Adolescent; Adult; Humans; Ketoconazole; Male; Penile Erection; Penis; Postoperative Complications | 1995 |
Routine prophylactic antifungal agents (clotrimazole, ketoconazole, and nystatin) in nontransplant/nonburned critically ill surgical and trauma patients.
Topics: Aged; Candida; Candidiasis; Clotrimazole; Colony Count, Microbial; Critical Illness; Cross Infection | 1994 |
Ketoconazole prevents acute respiratory failure in critically ill surgical patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; H | 1988 |
27 other studies available for ketoconazole and Complication, Postoperative
| Article | Year |
|---|---|
Assessment of the outcomes of the treatment of Cushing's disease in the hospitals of Castilla-La Mancha.
Topics: ACTH-Secreting Pituitary Adenoma; Adult; Combined Modality Therapy; Comorbidity; Craniotomy; Diabete | 2015 |
Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological | 2009 |
[Malassezia folliculitis: 21 cases].
Topics: Adolescent; Adult; Antifungal Agents; Dermatomycoses; Female; Fluconazole; Folliculitis; Humans; Ket | 2010 |
[Nosocomial urinary infection due to Trichosporon asahii. First two cases in Chile].
Topics: Amphotericin B; Antifungal Agents; Chile; Communicable Diseases, Emerging; Cross Infection; Drug Res | 2003 |
Use of oral ketoconazole to prevent postoperative erections following penile surgery.
Topics: Administration, Oral; Adolescent; Adult; Aged; Humans; Ketoconazole; Male; Middle Aged; Pain, Postop | 2004 |
Role of ketoconazole in renal transplant recipients.
Topics: Antifungal Agents; Humans; Ketoconazole; Kidney Transplantation; Mycoses; Postoperative Complication | 2005 |
Candida interface keratitis after deep anterior lamellar keratoplasty: clinical, microbiologic, histopathologic, and confocal microscopic reports.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis; Cornea; C | 2007 |
[Fungal infections -- always dangerous for immunosuppressed patients (author's transl)].
Topics: Adult; Candidiasis; Female; Humans; Imidazoles; Immunosuppression Therapy; Ketoconazole; Kidney Tran | 1981 |
[First human case of Drechslera longirostrata mycosis. Spondylodiscitis complicating prosthesis endocarditis. Treatment with combined ketoconazole and amphotericin B].
Topics: Adult; Amphotericin B; Antifungal Agents; Endocarditis; Female; Heart Valve Prosthesis; Humans; Imid | 1982 |
Leg granuloma due to Neocosmospora vasinfecta in a renal graft recipient.
Topics: Granuloma; Humans; Hypocreales; Ketoconazole; Kidney Transplantation; Leg; Male; Middle Aged; Mycose | 1993 |
Trends in antifungal use and epidemiology of nosocomial yeast infections in a university hospital.
Topics: Adult; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Candidiasis; Cross Infection; | 1999 |
Tinea capitis in adult renal transplant recipient.
Topics: Adult; Animals; Antifungal Agents; Cats; Female; Humans; Ketoconazole; Kidney Transplantation; Middl | 1999 |
[Epidemiology of fungemia in a university hospital; therapeutic incidence].
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Child, Pres | 1999 |
Clinical management of tacrolimus drug interactions in renal transplant patients.
Topics: Adult; Aged; Antifungal Agents; Candidiasis; Drug Interactions; Erythromycin; Female; Humans; Immuno | 1999 |
Fungal scleritis after cataract surgery. Successful outcome using itraconazole.
Topics: Administration, Oral; Antifungal Agents; Aspergillosis; Aspergillus flavus; Cataract Extraction; Eye | 1992 |
[The use of itraconazole in liver transplantation].
Topics: Antifungal Agents; Aspergillosis; Humans; Itraconazole; Ketoconazole; Liver Transplantation; Lung Di | 1992 |
Fungus ball: a cause of early obstructive uropathy in renal transplantation.
Topics: Candidiasis; Female; Humans; Ketoconazole; Kidney Transplantation; Postoperative Complications; Uret | 1992 |
Ulcerative tracheobronchitis after lung transplantation. A new form of invasive aspergillosis.
Topics: Adult; Antifungal Agents; Aspergillosis; Biopsy; Bronchi; Bronchitis; Female; Humans; Itraconazole; | 1991 |
Successful treatment of systemic blastomycosis with high-dose ketoconazole in a renal transplant recipient.
Topics: Aged; Blastomycosis; Chronic Disease; Dermatomycoses; Humans; Ketoconazole; Kidney Transplantation; | 1990 |
Itraconazole therapy for acute invasive pulmonary aspergillosis in heart transplantation.
Topics: Acute Disease; Adult; Aspergillosis; Cyclosporins; Heart Transplantation; Humans; Itraconazole; Keto | 1989 |
An outbreak of Candida parapsilosis endophthalmitis: analysis of strains by enzyme profile and antifungal susceptibility.
Topics: Amphotericin B; Candida; Candidiasis; Disease Outbreaks; Drug Contamination; Endophthalmitis; Flucyt | 1987 |
Successful treatment of Paecilomyces lilacinus endophthalmitis following cataract extraction with intraocular lens implantation.
Topics: Aged; Antifungal Agents; Cataract Extraction; Combined Modality Therapy; Endophthalmitis; Female; Hu | 1987 |
Candida albicans endophthalmitis following penetrating keratoplasty.
Topics: Administration, Oral; Candidiasis; Corneal Transplantation; Endophthalmitis; Humans; Ketoconazole; M | 1987 |
Localized cutaneous cryptococcosis successfully treated with ketoconazole.
Topics: Adult; Cryptococcosis; Dermatomycoses; Female; Humans; Ketoconazole; Kidney Transplantation; Postope | 1987 |
Cutaneous chromomycosis in renal transplant recipients. Successful management in two cases.
Topics: Abscess; Adult; Child; Chromoblastomycosis; Female; Granuloma; Humans; Ketoconazole; Kidney Transpla | 1985 |
Combined ketoconazole and amphotericin B treatment of acute disseminated histoplasmosis in a renal allograft recipient.
Topics: Acute Disease; Adult; Amphotericin B; Drug Combinations; Follow-Up Studies; Histoplasmosis; Humans; | 1985 |
Intraocular penetration of systemically administered antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Cataract Extraction; Drug Contamination; Eye; Flucyt | 1985 |