Page last updated: 2024-10-29

ketoconazole and Cirrhosis, Liver

ketoconazole has been researched along with Cirrhosis, Liver in 7 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
"We describe a previously healthy woman who developed liver cirrhosis as a sequela of acute hepatic injury that was induced by ketoconazole administration to treat onychomycosis."7.72Liver cirrhosis developed after ketoconazole-induced acute hepatic injury. ( Chang, R; Chang, YW; Dong, SH; Han, YS; Kim, BH; Kim, HJ; Kim, TH; Kim, YW; Lee, JI; Yang, DM, 2003)
" The first was a case of ketoconazole-induced hepatitis, and the second was a case of hepatitis C-related liver cirrhosis with hepatocellular carcinoma."7.71Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases. ( Chang, FY; Huang, DF; Huang, YH; Huang, YS; Huo, TI; Lee, SD; Lin, CC; Wu, JC, 2001)
"We describe a previously healthy woman who developed liver cirrhosis as a sequela of acute hepatic injury that was induced by ketoconazole administration to treat onychomycosis."3.72Liver cirrhosis developed after ketoconazole-induced acute hepatic injury. ( Chang, R; Chang, YW; Dong, SH; Han, YS; Kim, BH; Kim, HJ; Kim, TH; Kim, YW; Lee, JI; Yang, DM, 2003)
" The first was a case of ketoconazole-induced hepatitis, and the second was a case of hepatitis C-related liver cirrhosis with hepatocellular carcinoma."3.71Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases. ( Chang, FY; Huang, DF; Huang, YH; Huang, YS; Huo, TI; Lee, SD; Lin, CC; Wu, JC, 2001)
"Ketoconazole is a first orally available anti-fungal drug which has been reported as a potent inhibitor of human cytochrome P-450."1.51Hepatoprotective effect of ketoconazole in chronic liver injury model. ( Ahmed, M; Akhtar, U; Ali, G; Shehzad, U; Tayyeb, A, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhtar, U1
Ahmed, M1
Tayyeb, A1
Shehzad, U1
Ali, G1
Kim, TH1
Kim, BH1
Kim, YW1
Yang, DM1
Han, YS1
Dong, SH1
Kim, HJ1
Chang, YW1
Lee, JI1
Chang, R1
Lin, CC1
Wu, JC1
Huang, DF1
Huang, YS1
Huang, YH1
Huo, TI1
Chang, FY1
Lee, SD1
Andrés, A1
Morales, JM1
Farias, J1
Hernandez, G1
Gomez, M1
Calleja, J1
Moreno, E1
Rodicio, JL1
Martínez-Jordá, R1
Rodriguez-Sasiain, JM1
Suárez, E1
Calvo, R1
Kendrey, G1
Kovács, M1
Lake-Bakaar, G1
Cameron, HA1

Other Studies

7 other studies available for ketoconazole and Cirrhosis, Liver

ArticleYear
Hepatoprotective effect of ketoconazole in chronic liver injury model.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:3

    Topics: Actins; Animals; Carbon Tetrachloride; Cell Death; Chemical and Drug Induced Liver Injury; Disease M

2019
Liver cirrhosis developed after ketoconazole-induced acute hepatic injury.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:12

    Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Ketoconazole; Live

2003
Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:4

    Topics: Antifungal Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Hepati

2001
Acute renal failure after liver transplantation in patients treated with cyclosporine.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Acute Kidney Injury; Adult; Candidiasis; Cyclosporine; Female; Humans; Ketoconazole; Liver Cirrhosis

1992
Serum binding of ketoconazole in health and disease.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:5

    Topics: Adult; Blood Proteins; Female; Humans; Ketoconazole; Kidney Failure, Chronic; Liver Cirrhosis; Male;

1990
[Histopathologic observations on acute liver lesions in patients taking Nizoralt (ketokonazol)].
    Morphologiai es igazsagugyi orvosi szemle, 1988, Volume: 28, Issue:4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Ketoconazole; Liver; Liver Cirrhosis;

1988
CSM update: adverse drug reactions and the liver.
    British medical journal (Clinical research ed.), 1985, Sep-14, Volume: 291, Issue:6497

    Topics: Chemical and Drug Induced Liver Injury; Humans; Ketoconazole; Liver Cirrhosis

1985