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ketoconazole and Chromoblastomycosis

ketoconazole has been researched along with Chromoblastomycosis in 28 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Chromoblastomycosis: Scaly papule or warty growth, caused by five fungi, that spreads as a result of satellite lesions affecting the foot or leg. The extremity may become swollen and, at its distal portion, covered with various nodular, tumorous, verrucous lesions that resemble cauliflower. In rare instances, the disease may begin on the hand or wrist and involve the entire upper extremity. (Arnold, Odom, and James, Andrew's Diseases of the Skin, 8th ed, p362)

Research Excerpts

ExcerptRelevanceReference
"The efficacy and tolerability of itraconazole in chromoblastomycosis due to Fonsecaea pedrosoi were evaluated in a non-comparative open clinical trial in 19 Brazilian patients with histopathologically and mycologically proven active chromoblastomycosis."9.07Itraconazole in the treatment of chromoblastomycosis due to Fonsecaea pedrosoi. ( Bordignon, GF; Cauwenbergh, G; Fillus, JN; Lameira, RP; Purim, KS; Queiroz-Telles, F; Van Cutsem, J, 1992)
"The authors present the use of ketoconazole in 27 cases of paracoccidioidomycosis, eight of mycetoma, seven of chromomycosis, four of systemic candidiasis and one of lobomycosis."9.05Treatment of paracoccidioidomycosis, candidiasis, chromomycosis, lobomycosis, and mycetoma with ketoconazole. ( Cucé, LC; Sampaio, SA; Wroclawski, EL, 1980)
"The results of long-term itraconazole therapy in 10 patients with active chromoblastomycosis due to F."7.67Treatment of chromoblastomycosis with itraconazole. ( Arango, M; de Bedout, C; Gomez, I; Gonzalez, A; Restrepo, A, 1988)
"Our experience in the treatment of chronic mucocutaneous candidiasis with ketoconazole is reviewed."7.66Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients. ( Horsburgh, CR; Kirkpatrick, CH, 1983)
"Chromoblastomycosis is a rare, chronic, cutaneous infection caused by a group of dematiacaeous fungi."5.29A case of chromoblastomycosis responding to treatment with itraconazole. ( Barker, JN; Hay, RJ; Smith, CH, 1993)
"The efficacy and tolerability of itraconazole in chromoblastomycosis due to Fonsecaea pedrosoi were evaluated in a non-comparative open clinical trial in 19 Brazilian patients with histopathologically and mycologically proven active chromoblastomycosis."5.07Itraconazole in the treatment of chromoblastomycosis due to Fonsecaea pedrosoi. ( Bordignon, GF; Cauwenbergh, G; Fillus, JN; Lameira, RP; Purim, KS; Queiroz-Telles, F; Van Cutsem, J, 1992)
"The authors present the use of ketoconazole in 27 cases of paracoccidioidomycosis, eight of mycetoma, seven of chromomycosis, four of systemic candidiasis and one of lobomycosis."5.05Treatment of paracoccidioidomycosis, candidiasis, chromomycosis, lobomycosis, and mycetoma with ketoconazole. ( Cucé, LC; Sampaio, SA; Wroclawski, EL, 1980)
"The results of long-term itraconazole therapy in 10 patients with active chromoblastomycosis due to F."3.67Treatment of chromoblastomycosis with itraconazole. ( Arango, M; de Bedout, C; Gomez, I; Gonzalez, A; Restrepo, A, 1988)
"Our experience in the treatment of chronic mucocutaneous candidiasis with ketoconazole is reviewed."3.66Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients. ( Horsburgh, CR; Kirkpatrick, CH, 1983)
"Treatment of chromoblastomycosis is frequently difficult and unsatisfactory."2.38Treatment of chromoblastomycosis. ( Milburn, PB; Tuffanelli, L, 1990)
"Chromoblastomycosis is a rare, chronic, cutaneous infection caused by a group of dematiacaeous fungi."1.29A case of chromoblastomycosis responding to treatment with itraconazole. ( Barker, JN; Hay, RJ; Smith, CH, 1993)
"Although blastomycosis is endemic in North America, only 4 cases have been identified in Natal during the last 25 years, and all presented with atypical clinical features."1.28Tropical mycoses. ( Bayles, MA, 1992)
"Although blastomycosis is endemic in North America, only four cases have been identified in Natal during the last 25 years and all presented with atypical clinical features."1.28[Tropical mycoses]. ( Bayles, MA, 1991)
"Cutaneous chromomycosis developed in an elderly man with steroid-dependent chronic obstructive pulmonary disease."1.28Chromomycosis in a steroid-dependent patient with chronic obstructive pulmonary disease. ( Foulis, PR; Greene, JN; Yangco, BG, 1990)
"We describe a case of chromomycosis of the lower extremities that is being successfully treated with ketoconazole and 5-fluorocytosine (5-FC) after treatment with ketoconazole alone had failed."1.27Treatment of chromomycosis with ketoconazole and 5-fluorocytosine. ( Gombert, ME; Green, KM; Shalita, AR; Silber, JG, 1983)
"A case of chromomycosis with an evolution of 25 years, in a caucasoid man, aged 57, living in Mozambique, is reported."1.27[Chromomycosis]. ( Cabrita, J; Cachão, P; Rocha, MM; Rodrigo, JG, 1987)
"Cutaneous chromomycosis occurred in two renal transplant recipients from the south central United States."1.27Cutaneous chromomycosis in renal transplant recipients. Successful management in two cases. ( Gray, GF; Gregg, CR; Richie, RE; Wackym, PA, 1985)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's11 (39.29)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrade, TS1
Castro, LG2
Nunes, RS1
Gimenes, VM1
Cury, AE1
Marques, SG1
Pedrozo Silva, CM1
Resende, MA1
Andreata, LS1
Costa, JM1
Iutskovskiĭ, AD1
Cucé, LC1
Wroclawski, EL1
Sampaio, SA1
South, DA1
Brass, C1
Stevens, DA1
Mittag, H1
Kreysel, HW1
McBurney, EI1
Horsburgh, CR1
Kirkpatrick, CH1
Silber, JG1
Gombert, ME1
Green, KM1
Shalita, AR1
Stamm, AM1
Dismukes, WE1
Deutsch, PH1
Quintiliani, R1
Smith, CH1
Barker, JN1
Hay, RJ1
Bayles, MA2
Queiroz-Telles, F1
Purim, KS1
Fillus, JN1
Bordignon, GF1
Lameira, RP1
Van Cutsem, J1
Cauwenbergh, G1
Paul, C1
Dupont, B1
Pialoux, G1
Avril, MF1
Pradinaud, R2
Kumar, B1
Kaur, I1
Chakrabarti, A1
Sharma, VK1
Bolzinger, T1
Defaveri, J1
Graybill, JR1
Tuffanelli, L1
Milburn, PB1
Greene, JN1
Foulis, PR1
Yangco, BG1
Restrepo, A1
Gonzalez, A1
Gomez, I1
Arango, M1
de Bedout, C1
Heyl, T1
Cachão, P1
Rocha, MM1
Cabrita, J1
Rodrigo, JG1
Krempl-Lamprecht, L1
Luderschmidt, C1
Wehrmann, W1
Atukorala, DN1
Pothupitiya, GM1
Wackym, PA1
Gray, GF1
Richie, RE1
Gregg, CR1

Reviews

3 reviews available for ketoconazole and Chromoblastomycosis

ArticleYear
Current therapy of pulmonary and disseminated fungal diseases.
    Chest, 1983, Volume: 83, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Chromoblastomycosis; C

1983
Ketoconazole.
    Connecticut medicine, 1984, Volume: 48, Issue:4

    Topics: Candidiasis; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Chemical Phenomena; Chemistry; C

1984
Treatment of chromoblastomycosis.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:4 Pt 1

    Topics: Antifungal Agents; Chromoblastomycosis; Drug Administration Schedule; Humans; Itraconazole; Ketocona

1990

Trials

2 trials available for ketoconazole and Chromoblastomycosis

ArticleYear
Treatment of paracoccidioidomycosis, candidiasis, chromomycosis, lobomycosis, and mycetoma with ketoconazole.
    International journal of dermatology, 1980, Volume: 19, Issue:7

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Candidiasis; Chromoblastomycosis; Clinical Trials as Top

1980
Itraconazole in the treatment of chromoblastomycosis due to Fonsecaea pedrosoi.
    International journal of dermatology, 1992, Volume: 31, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Chromoblastomycosis; Female; Humans; Itraconazole

1992

Other Studies

23 other studies available for ketoconazole and Chromoblastomycosis

ArticleYear
Susceptibility of sequential Fonsecaea pedrosoi isolates from chromoblastomycosis patients to antifungal agents.
    Mycoses, 2004, Volume: 47, Issue:5-6

    Topics: Amphotericin B; Antifungal Agents; Ascomycota; Chromoblastomycosis; Humans; Itraconazole; Ketoconazo

2004
Chromoblastomycosis caused by Rhinocladiella aquaspersa.
    Medical mycology, 2004, Volume: 42, Issue:3

    Topics: Arm; Ascomycota; Biopsy; Brazil; Chromoblastomycosis; Face; Forehead; Humans; Ketoconazole; Leg; Mal

2004
[Successful treatment of chromomycosis with nizoral].
    Vestnik dermatologii i venerologii, 1984, Issue:7

    Topics: Adult; Chromoblastomycosis; Humans; Ketoconazole; Male

1984
Chromohyphomycosis. Treatment wit ketoconazole.
    Archives of dermatology, 1981, Volume: 117, Issue:5

    Topics: Antifungal Agents; Biopsy; Chromoblastomycosis; Female; Humans; Imidazoles; Ketoconazole; Middle Age

1981
[Clinical features, diagnosis and therapy of chromomycosis].
    Mykosen, 1982, Volume: 25, Issue:8

    Topics: Adult; Antifungal Agents; Chromoblastomycosis; Cladosporium; Humans; Imidazoles; Ketoconazole; Male;

1982
Chromoblastomycosis treatment with ketoconazole.
    Cutis, 1982, Volume: 30, Issue:6

    Topics: Aged; Antifungal Agents; Arm; Chromoblastomycosis; Humans; Imidazoles; Ketoconazole; Male; Mitospori

1982
Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients.
    The American journal of medicine, 1983, Jan-24, Volume: 74, Issue:1B

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis; Candidiasis, Chronic Mucocutaneous; Chemical and

1983
Treatment of chromomycosis with ketoconazole and 5-fluorocytosine.
    Journal of the American Academy of Dermatology, 1983, Volume: 8, Issue:2

    Topics: Adult; Antifungal Agents; Chromoblastomycosis; Drug Synergism; Drug Therapy, Combination; Humans; Im

1983
A case of chromoblastomycosis responding to treatment with itraconazole.
    The British journal of dermatology, 1993, Volume: 128, Issue:4

    Topics: Antifungal Agents; Chromoblastomycosis; Humans; Itraconazole; Ketoconazole; Male; Middle Aged

1993
Tropical mycoses.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Adult; Aged; Antifungal Agents; Blastomycosis; Chromoblastomycosis; Drug Therapy, Combination; Femal

1992
Chromomycosis: a therapeutic challenge.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 15, Issue:3

    Topics: Antifungal Agents; Chromoblastomycosis; Humans; Itraconazole; Ketoconazole

1992
Chromoblastomycosis with malignant transformation and cutaneous-synovial secondary localization. The potential therapeutic role of itraconazole.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1991, Volume: 29, Issue:5

    Topics: Aged; Antifungal Agents; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chromoblastomyco

1991
Treatment of deep mycoses with itraconazole.
    Mycopathologia, 1991, Volume: 115, Issue:3

    Topics: Adult; Amphotericin B; Antifungal Agents; Antitubercular Agents; Aspergillosis; Child; Chromoblastom

1991
[Tropical mycoses].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Volume: 86 Suppl 1

    Topics: Antifungal Agents; Blastomycosis; Chromoblastomycosis; Clinical Trials as Topic; Female; Histoplasmo

1991
Treatment of chromoblastomycosis.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 1

    Topics: Antifungal Agents; Chromoblastomycosis; Drug Combinations; Flucytosine; Humans; Itraconazole; Ketoco

1991
Treatment of chronic murine chromoblastomycosis with the triazole SCH39304.
    The American journal of tropical medicine and hygiene, 1990, Volume: 42, Issue:6

    Topics: Animals; Antifungal Agents; Chromoblastomycosis; Chronic Disease; Disease Models, Animal; Female; It

1990
Chromomycosis in a steroid-dependent patient with chronic obstructive pulmonary disease.
    The American journal of the medical sciences, 1990, Volume: 299, Issue:1

    Topics: Aspergillus; Chromoblastomycosis; Cladosporium; Humans; Ketoconazole; Lung Diseases, Obstructive; Ma

1990
Treatment of chromoblastomycosis with itraconazole.
    Annals of the New York Academy of Sciences, 1988, Volume: 544

    Topics: Antifungal Agents; Chromoblastomycosis; Female; Follow-Up Studies; Humans; Itraconazole; Ketoconazol

1988
Treatment of chromomycosis with itraconazole.
    The British journal of dermatology, 1985, Volume: 112, Issue:6

    Topics: Aged; Chromoblastomycosis; Female; Humans; Itraconazole; Ketoconazole; Male; Middle Aged

1985
[Chromomycosis].
    Medicina cutanea ibero-latino-americana, 1987, Volume: 15, Issue:5

    Topics: Amphotericin B; Chromoblastomycosis; Flucytosine; Humans; Ketoconazole; Male; Middle Aged; Mozambiqu

1987
[Chromomycosis caused by Fonsecaea compacta (Carrion 1940) with secondary phaeohyphomycotic infection caused by Phaeosclera dermatioides (Sigler 1981)].
    Mykosen, 1987, Volume: 30, Issue:10

    Topics: Adult; Chromoblastomycosis; Dermatomycoses; Foot Dermatoses; Humans; Ketoconazole; Male; Microscopy,

1987
Treatment of chromomycosis with a combination of ketoconazole and 5-fluorocytosine.
    The Ceylon medical journal, 1985, Volume: 30, Issue:4

    Topics: Adult; Aged; Chromoblastomycosis; Drug Therapy, Combination; Flucytosine; Humans; Ketoconazole; Male

1985
Cutaneous chromomycosis in renal transplant recipients. Successful management in two cases.
    Archives of internal medicine, 1985, Volume: 145, Issue:6

    Topics: Abscess; Adult; Child; Chromoblastomycosis; Female; Granuloma; Humans; Ketoconazole; Kidney Transpla

1985