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ketoconazole and Central Nervous System Diseases

ketoconazole has been researched along with Central Nervous System Diseases in 7 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Ketoconazole (KTZ) has largely replaced amphotericin B as first-line therapy for blastomycosis."7.68Asymptomatic blastomycosis of the central nervous system with progression in patients given ketoconazole therapy: a report of two cases. ( Kaufman, L; Perlino, CA; Yancey, RW, 1991)
"Ketoconazole (KTZ) has largely replaced amphotericin B as first-line therapy for blastomycosis."3.68Asymptomatic blastomycosis of the central nervous system with progression in patients given ketoconazole therapy: a report of two cases. ( Kaufman, L; Perlino, CA; Yancey, RW, 1991)
" We studied the ventricular and lumbar cerebrospinal fluid penetration of ketoconazole and the responses to therapy in two patients receiving ketoconazole orally, 800 mg daily, and amphotericin B intraventricularly for meningeal and extrameningeal coccidioidomycosis."3.66High-dose ketoconazole for treatment of fungal infections of the central nervous system. ( Craven, PC; Dismukes, WE; Graybill, JR; Jorgensen, JH; Levine, BE, 1983)
"Histoplasmosis is an important cause of morbidity and death in HIV-infected patients."1.30Histoplasmosis: update 1998. ( Brooks, JT; Wheat, LJ, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Craven, PC1
Graybill, JR1
Jorgensen, JH1
Dismukes, WE1
Levine, BE1
Brooks, JT1
Wheat, LJ1
Morato-Fernandez, RN1
Beraldo, PS1
Masini, M1
Costa, PH1
Webster, G1
Yancey, RW1
Perlino, CA1
Kaufman, L1
Jennings, FW1
Krivoy, A1
Casale, E1
Valdivia, RD1
Silva, V1
Gonzalez, A1

Reviews

2 reviews available for ketoconazole and Central Nervous System Diseases

ArticleYear
[Paracoccidioidomycosis of intramedullar and cerebral localization].
    Arquivos de neuro-psiquiatria, 1991, Volume: 49, Issue:2

    Topics: Central Nervous System Diseases; Humans; Ketoconazole; Male; Middle Aged; Paracoccidioidomycosis

1991
Seborrheic dermatitis.
    International journal of dermatology, 1991, Volume: 30, Issue:12

    Topics: Antifungal Agents; Central Nervous System Diseases; Dermatitis; Dermatitis, Seborrheic; Humans; Keto

1991

Other Studies

5 other studies available for ketoconazole and Central Nervous System Diseases

ArticleYear
High-dose ketoconazole for treatment of fungal infections of the central nervous system.
    Annals of internal medicine, 1983, Volume: 98, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Coccidioidomycosis; Drug Therapy

1983
Histoplasmosis: update 1998.
    AIDS clinical care, 1998, Volume: 10, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Central Nervous System Dis

1998
Asymptomatic blastomycosis of the central nervous system with progression in patients given ketoconazole therapy: a report of two cases.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Aged; Blastomycosis; Central Nervous System Diseases; Dermatomycoses; Humans; Ketoconazole; Lung Dis

1991
Chemotherapy of chronic trypanosomiasis: the failure of ketoconazole to cure murine infections of Trypanosoma brucei with central nervous system involvement.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:2

    Topics: Animals; Central Nervous System Diseases; Chronic Disease; Drug Therapy, Combination; Ketoconazole;

1988
Parasitosis and mycosis of the central nervous system: 20 years of experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1988, Volume: 4, Issue:2

    Topics: Central Nervous System Diseases; Child; Child, Preschool; Cysticercosis; Female; Humans; Infant; Ket

1988