ketoconazole has been researched along with Carcinoma, Small Cell in 6 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 7.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 3.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "Treatment with ketoconazole (KCZ) resulted in significant suppression of serum cortisol levels." | 1.28 | The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome. ( Brigham, B; Hoffman, DM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Winquist, EW | 1 |
| Laskey, J | 2 |
| Crump, M | 1 |
| Khamsi, F | 2 |
| Shepherd, FA | 3 |
| Mawer, EB | 1 |
| Hayes, ME | 1 |
| Heys, SE | 1 |
| Davies, M | 1 |
| White, A | 1 |
| Stewart, MF | 1 |
| Smith, GN | 1 |
| Evans, WK | 2 |
| Goss, PE | 1 |
| Johansen, E | 1 |
| Hoffman, DM | 1 |
| Brigham, B | 1 |
| Impens, N | 1 |
| De Greve, J | 1 |
| De Beule, K | 1 |
| Meysman, M | 1 |
| De Beuckelaere, S | 1 |
| Schandevyl, W | 1 |
| Hoffert, B | 1 |
| Emery, G | 1 |
| Trachtenberg, J | 1 |
6 other studies available for ketoconazole and Carcinoma, Small Cell
| Article | Year |
|---|---|
Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Carcinoma, Small Cell; Caus | 1995 |
Constitutive synthesis of 1,25-dihydroxyvitamin D3 by a human small cell lung cancer cell line.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcifediol; Calcitriol; Calcium; Carcinoma, Small Cell; C | 1994 |
Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Smal | 1992 |
The use of ketoconazole in ectopic adrenocorticotropic hormone syndrome.
Topics: ACTH Syndrome, Ectopic; Carcinoma, Small Cell; Female; Humans; Ketoconazole; Lung Neoplasms; Middle | 1991 |
Oral treatment with itraconazole of aspergilloma in cavitary lung cancer.
Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Carcinoma, Small Cell; Humans; Itraconazole | 1990 |
Ketoconazole. Use in the treatment of ectopic adrenocorticotropic hormone production and Cushing's syndrome in small-cell lung cancer.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoma, Small Cell; Cushing Syndrome; Humans; Hydro | 1985 |