ketoconazole has been researched along with Carcinoma, Renal Cell in 1 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole (KTZ) is an FDA approved anti-fungal medication which has been shown to suppress exosome biogenesis and secretion, yet its role in ccRCC has not been identified." | 1.62 | Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma. ( Abdel-Mageed, AB; Barata, PC; Boulares, AH; Datta, A; Greenberg, JW; Kim, H; Krane, LS; Moustafa, AA, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenberg, JW | 1 |
| Kim, H | 1 |
| Moustafa, AA | 1 |
| Datta, A | 1 |
| Barata, PC | 1 |
| Boulares, AH | 1 |
| Abdel-Mageed, AB | 1 |
| Krane, LS | 1 |
1 other study available for ketoconazole and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma.
Topics: Adult; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Repositioning; Drug Resistance, Neoplasm; Drug | 2021 |