ketoconazole has been researched along with Carcinoma, Non-Small Cell Lung in 3 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, continuous oral dosing results in progressive decline in plasma drug concentrations, which is associated with relapse and resistance to this retinoid." | 2.67 | Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole. ( DeGrazia, F; Francis, PA; Huselton, C; Kris, MG; Muindi, JR; Orazem, JP; Rigas, JR; Warrell, RP; Young, CW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muindi, JR | 2 |
| Young, CW | 2 |
| Warrell, RP | 2 |
| Rigas, JR | 1 |
| Francis, PA | 1 |
| Kris, MG | 1 |
| Huselton, C | 1 |
| DeGrazia, F | 1 |
| Orazem, JP | 1 |
| Niimi, T | 1 |
| Kajita, M | 1 |
| Saito, H | 1 |
1 review available for ketoconazole and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Clinical pharmacology of all-trans retinoic acid.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Lung Neoplasms | 1994 |
1 trial available for ketoconazole and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole.
Topics: Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug | 1993 |
1 other study available for ketoconazole and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Necrotizing bronchial aspergillosis in a patient receiving neoadjuvant chemotherapy for non-small cell lung carcinoma.
Topics: Aged; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus | 1991 |