ketoconazole has been researched along with Carcinoid Tumor in 8 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 7.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 7.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated." | 3.91 | Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019) |
| "To evaluate the safety and efficacy of ketoconazole treatment in the management of patients with paraneoplastic Cushing's syndrome (CS) secondary to ectopic adrenocorticotropin (ACTH) production by malignant neoplasms (ECS)." | 3.69 | Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. ( Crump, M; Khamsi, F; Laskey, J; Shepherd, FA; Winquist, EW, 1995) |
| "Six to 10 months after hypercorticism was cured with ketoconazole and bilateral adrenalectomy, a thymic mass 2 to 5 cm in length was detected by computerized tomography or magnetic resonance imaging in all 3 patients." | 1.29 | [Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases]. ( Caillé, JM; Catargi, B; Drouillard, J; Greselle, JF; Laurent, F; Martigne, C; Roger, P; Tabarin, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ilie, MD | 1 |
| Raverot, V | 1 |
| Tronc, F | 1 |
| Vasiljevic, A | 1 |
| Borson-Chazot, F | 1 |
| Raverot, G | 1 |
| Winquist, EW | 1 |
| Laskey, J | 1 |
| Crump, M | 1 |
| Khamsi, F | 1 |
| Shepherd, FA | 1 |
| Tabarin, A | 1 |
| Catargi, B | 1 |
| Laurent, F | 1 |
| Greselle, JF | 1 |
| Martigne, C | 1 |
| Caillé, JM | 1 |
| Drouillard, J | 1 |
| Roger, P | 1 |
| Parthiban, A | 1 |
| Sundaram, DS | 1 |
| Reddy, DJ | 1 |
| Girinath, MR | 1 |
| Prabhakaran, R | 1 |
| Chidambaranathan, N | 1 |
| Pérez Gracia, A | 1 |
| Ramírez, L | 1 |
| Herrero, V | 1 |
| Espinosa, J | 1 |
| Steen, RE | 1 |
| Kapelrud, H | 1 |
| Haug, E | 1 |
| Frey, H | 1 |
| Kornely, E | 1 |
| Schlaghecke, R | 1 |
| Horster, FA | 1 |
| Farwell, AP | 1 |
| Devlin, JT | 1 |
| Stewart, JA | 1 |
8 other studies available for ketoconazole and Carcinoid Tumor
| Article | Year |
|---|---|
Cabergoline in severe ectopic or occult Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cabergoline; Carcinoid Tumor; Cushing Syndrome; Dopamine Agonis | 2019 |
Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Carcinoma, Small Cell; Caus | 1995 |
[Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases].
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adult; Carcinoid Tumor; Cushing Syndrome; Drug Therapy, | 1993 |
Octreotide and ketoconazole for persistent ectopic ACTH Cushing's disease due to mediastinal carcinoid.
Topics: Adrenocorticotropic Hormone; Adult; Antineoplastic Agents, Hormonal; Carcinoid Tumor; Chemotherapy, | 1995 |
[Treatment with ketoconazole of Cushing's syndrome due to ectopic secretion of ACTH].
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Humans; Ketoconazole | 1992 |
In vivo and in vitro inhibition by ketoconazole of ACTH secretion from a human thymic carcinoid tumour.
Topics: Adrenocorticotropic Hormone; Adult; Carcinoid Tumor; Circadian Rhythm; Corticotropin-Releasing Hormo | 1991 |
Palliative therapy of an ectopic Cushing's syndrome due to a metastatic carcinoid tumor.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoid Tumor; Combined Modality Therapy; Cushing Syndrome; Dose-Re | 1991 |
Total suppression of cortisol excretion by ketoconazole in the therapy of the ectopic adrenocorticotropic hormone syndrome.
Topics: Carcinoid Tumor; Cushing Syndrome; Female; Humans; Hydrocortisone; Ketoconazole; Middle Aged; Parane | 1988 |