ketoconazole has been researched along with Cancer of Liver in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, HN; Chen, Y; Huang, C; Huang, Z; Lei, Y; Liu, J; Luo, M; Peng, Y; Wang, K; Wei, Y; Zhang, L; Zhang, Z; Zhou, ZG | 1 |
| Peiró, I; Simó-Servat, A; Villabona, C | 1 |
| Chen, HN; Chen, Y; Huang, C; Wei, Y; Zhou, ZG | 1 |
| Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A | 1 |
| Aggarwal, R; Carducci, M; George, D; Halabi, S; Kantoff, P; Kelly, WK; Mahoney, JF; Millard, F; Monk, JP; Morris, MJ; Small, EJ; Stadler, WM | 1 |
| Davi', MV; Francia, G; Salgarello, M | 1 |
| Chengqing, L; Chenming, N; Tao, L; Xiaoyang, L | 1 |
| Anwar-Mohamed, A; Brocks, DR; El-Kadi, AO; El-Sherbeni, AA; Hamdy, DA; Korashy, HM | 1 |
| Capella, C; Colombo, P; Finzi, G; Ghezzi, F; La Rosa, S; Marando, A | 1 |
| Chen, CF; Chen, CH; Chen, LC; Ho, YS; Liang, YC; Lin, CH; Lin, JK; Lin, SY; Wang, YJ; Yu, CF | 1 |
| Krambovitis, E; Tsatsakis, AM; Tzanakakis, GN; Vezeridis, MP | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
| Brocks, DR; El-Kadi, AO; Korashy, HM; Shayeganpour, A | 1 |
| Baker, SD; Huang, H; Kalpana, G; Li, H; Mani, S; Redinbo, MR; Sinz, M; Staudinger, J; Teotico, DG; Wang, H | 1 |
| André, F; Cohen, M; Cömezoglu, SN; Comprelli, A; Goel, S; Goldberg, G; Horwitz, SB; Humphreys, WG; Iacono, L; Jayabalan, D; Ly, VT; Mani, S; McDaid, H; Perrin, L; Xu, C; Zhang, D | 1 |
| Kolts, BE; Langfitt, M | 1 |
| Feldman, D; Loose, DS; Stover, EP | 1 |
| Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ | 1 |
| Chen, RJ; Ho, YS; Lin, JK; Liu, HL; Tsai, PW; Yu, CF | 1 |
| Chang, FY; Huang, DF; Huang, YH; Huang, YS; Huo, TI; Lee, SD; Lin, CC; Wu, JC | 1 |
| Horster, FA; Kornely, E; Schlaghecke, R | 1 |
| Agarwal, KC; Tzanakakis, GN; Veronikis, DK; Vezeridis, MP | 1 |
| Agarwal, KC; Tzanakakis, GN; Vezeridis, MP | 1 |
| Gupta, S; Korula, J | 1 |
| Kessler, HA; Pottage, JC | 1 |
| Cohen, LH; Griffioen, M; Havekes, L; Kempen, HJ; van Son, K; Verboom, H | 1 |
| Altieri, E; Contreras, P; Gac, A; Ibarra, A; Liberman, C; Ravanal, M; Rojas, A; Serón-Ferré, M | 1 |
| Bae, S; Cho, Y; Choi, J; Kang, JA; Kim, YC; Lee, D; Lim, C; Park, M; Park, SG; Seo, J | 1 |
| Abu Rabah, RR; Al Shamma, SA; Al-Tel, TH; Anbar, HS; El-Gamal, MI; Elgendy, SM; Omar, HA; Sebastian, A; Shehata, MK; Sultan, S; Tarazi, H; Vunnam, S; Zaraei, SO | 1 |
2 trial(s) available for ketoconazole and Cancer of Liver
| Article | Year |
|---|---|
The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (
Topics: Aged; Androgen Antagonists; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Chemotherapy, Adjuvant; Disease Progression; Docetaxel; Drug Therapy, Combination; Follow-Up Studies; Humans; International Agencies; Ketoconazole; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Orchiectomy; Prednisone; Prognosis; Prostatic Neoplasms; Retrospective Studies; Survival Rate; Taxoids | 2013 |
The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Computational Biology; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Epothilones; Female; Genital Neoplasms, Female; Humans; Ketoconazole; Leukocytes, Mononuclear; Liver; Liver Neoplasms; Male; Microsomes, Liver; Middle Aged; Neoplasms; Prostatic Neoplasms; Tubulin Modulators | 2008 |
27 other study(ies) available for ketoconazole and Cancer of Liver
| Article | Year |
|---|---|
Ketoconazole exacerbates mitophagy to induce apoptosis by downregulating cyclooxygenase-2 in hepatocellular carcinoma.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclooxygenase 2; Cytochrome P-450 CYP3A Inhibitors; Down-Regulation; Hepatocytes; Humans; Ketoconazole; Liver Neoplasms; Mitophagy | 2019 |
Corticotropin secreting pancreatic neuroendocrine tumour, a therapeutic management challenge. A presentation of 2 cases.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Chromogranins; Combined Modality Therapy; Embolization, Therapeutic; Everolimus; Female; Fludrocortisone; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Peptides, Cyclic; Phenylurea Compounds; Quinolines; Somatostatin; Spironolactone; Splenectomy; Sunitinib | 2019 |
A novel role for ketoconazole in hepatocellular carcinoma treatment: linking PTGS2 to mitophagy machinery.
Topics: Autophagy; Carcinoma, Hepatocellular; Cyclooxygenase 2; Humans; Ketoconazole; Liver Neoplasms; Mitophagy; Protein Kinases | 2019 |
Cabergoline in severe ectopic or occult Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cabergoline; Carcinoid Tumor; Cushing Syndrome; Dopamine Agonists; Female; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Intraductal Neoplasms; Rectal Neoplasms; Steroid Synthesis Inhibitors; Thymus Neoplasms; Treatment Outcome | 2019 |
Positive (68)Ga-DOTATOC-PET/CT after cortisol level control during ketoconazole treatment in a patient with liver metastases from a pancreatic neuroendocrine tumor and ectopic Cushing syndrome.
Topics: Cushing Syndrome; Gallium Radioisotopes; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Male; Middle Aged; Multimodal Imaging; Octreotide; Pancreatic Neoplasms; Positron-Emission Tomography; Tomography, X-Ray Computed | 2015 |
Drug-drug interation prediction between ketoconazole and anti-liver cancer drug Gomisin G.
Topics: Antineoplastic Agents; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxoles; Drug Interactions; Humans; Ketoconazole; Lignans; Liver; Liver Neoplasms; Molecular Docking Simulation; Plant Extracts; Schisandra | 2015 |
Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells.
Topics: Animals; Antifungal Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Hep G2 Cells; Humans; Ketoconazole; Liver Neoplasms; Mice; RNA, Messenger; Stereoisomerism | 2016 |
Cushing's syndrome due to a pancreatic neuroendocrine tumor metastatic to the ovaries: a clinicopathological description of a case.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoma, Neuroendocrine; Cushing Syndrome; Fatal Outcome; Female; Humans; Hysterectomy; Ketoconazole; Liver Neoplasms; Lymph Nodes; Ovarian Neoplasms; Pancreatic Neoplasms | 2011 |
Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Topics: Animals; Apoptosis; Baculoviridae; Carcinoma, Hepatocellular; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Fragmentation; Drug Interactions; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Insecta; Ketoconazole; Liver Neoplasms; Microsomes; Recombinant Proteins; Terfenadine; Tumor Cells, Cultured | 2002 |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Animals; Antineoplastic Agents; Dinoprostone; Humans; Injections, Intraperitoneal; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Thromboxane B2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |
Induction of cytochrome P450 1A1 by ketoconazole and itraconazole but not fluconazole in murine and human hepatoma cell lines.
Topics: Animals; Antifungal Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Fluconazole; Genes, Reporter; Humans; Itraconazole; Ketoconazole; Liver Neoplasms; Luciferases; Mice; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription, Genetic | 2007 |
Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Genes, Reporter; Humans; Ketoconazole; Liver Neoplasms; Luciferases; Pregnane X Receptor; Receptors, Steroid | 2007 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Cimetidine; Fatty Liver; Female; Hepatic Artery; Hepatic Veins; Humans; Ketoconazole; Liver; Liver Diseases; Liver Neoplasms; Methyldopa; Necrosis; Nitrofurantoin; Peliosis Hepatis; Portal Vein; Valproic Acid; Verapamil | 1984 |
Ketoconazole binds to glucocorticoid receptors and exhibits glucocorticoid antagonist activity in cultured cells.
Topics: Animals; Antifungal Agents; Carcinoma, Hepatocellular; Cells, Cultured; Clotrimazole; Dexamethasone; Humans; Imidazoles; Ketoconazole; Liver Neoplasms; Piperazines; Rats; Receptors, Glucocorticoid; Receptors, Steroid; Tyrosine Transaminase | 1983 |
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E | 1993 |
Ketoconazole-induced apoptosis through P53-dependent pathway in human colorectal and hepatocellular carcinoma cell lines.
Topics: Adenocarcinoma; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Colorectal Neoplasms; Humans; Ketoconazole; Liver; Liver Neoplasms; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases.
Topics: Antifungal Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Hepatitis C; Histamine H2 Antagonists; Humans; Jaundice; Ketoconazole; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Ranitidine; Severity of Illness Index; Stevens-Johnson Syndrome | 2001 |
Palliative therapy of an ectopic Cushing's syndrome due to a metastatic carcinoid tumor.
Topics: ACTH Syndrome, Ectopic; Adult; Carcinoid Tumor; Combined Modality Therapy; Cushing Syndrome; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Male; Neoplasms, Unknown Primary; Octreotide; Palliative Care | 1991 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured; Verapamil | 1991 |
Inhibition of hepatic metastasis from a human pancreatic adenocarcinoma (RWP-2) in the nude mouse by prostacyclin, forskolin, and ketoconazole.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colforsin; Epoprostenol; Humans; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured | 1990 |
Failure of ketoconazole as anti-androgen therapy in nonresectable primary hepatocellular carcinoma.
Topics: Adult; Aged; alpha-Fetoproteins; Androgen Antagonists; Carcinoma, Hepatocellular; Female; Humans; Ketoconazole; Liver Neoplasms; Male; Middle Aged | 1988 |
Inhibition of in vitro HBsAg production by amphotericin B and ketoconazole.
Topics: Amphotericin B; Antigens, Neoplasm; Antiviral Agents; Carcinoma, Hepatocellular; Cell Line; Depression, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatitis B; Hepatitis B Surface Antigens; Humans; Ketoconazole; Liver Neoplasms; Neoplasm Proteins; Vidarabine | 1985 |
Effect of ketoconazole on cholesterol synthesis and on HMG-CoA reductase and LDL-receptor activities in Hep G2 cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketoconazole; Lipoproteins, LDL; Liver Neoplasms; Receptors, LDL | 1987 |
Adrenal rest tumor of the liver causing Cushing's syndrome: treatment with ketoconazole preceding an apparent surgical cure.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adrenal Rest Tumor; Adult; Cushing Syndrome; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Paraneoplastic Endocrine Syndromes; Preoperative Care | 1985 |
Entry inhibition of hepatitis B virus using cyclosporin O derivatives with peptoid side chain incorporation.
Topics: Antiviral Agents; Cyclosporins; Hepatitis B; Hepatitis B virus; Humans; Imidazoles; Liver Neoplasms; Organic Anion Transporters, Sodium-Dependent; Peptoids; Sulfonamides; Symporters; Thiophenes; Virus Internalization | 2022 |
Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Structure-Activity Relationship | 2022 |