ketoconazole has been researched along with Cancer of Colon in 4 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachidonic acid lipoxygenases and cytochrome P-450 enzymes, were tested in human colon and breast cancer cell lines." | 3.68 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. ( Coudray, AM; Fagot, D; Forgue-Lafitte, ME; Mester, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esposito, G | 1 |
| Gigli, S | 1 |
| Seguella, L | 1 |
| Nobile, N | 1 |
| D'Alessandro, A | 1 |
| Pesce, M | 1 |
| Capoccia, E | 1 |
| Steardo, L | 1 |
| Cirillo, C | 1 |
| Cuomo, R | 1 |
| Sarnelli, G | 1 |
| Kota, BP | 1 |
| Allen, JD | 1 |
| Roufogalis, BD | 1 |
| Wang, YJ | 1 |
| Jeng, JH | 1 |
| Chen, RJ | 1 |
| Tseng, H | 1 |
| Chen, LC | 1 |
| Liang, YC | 1 |
| Lin, CH | 1 |
| Chen, CH | 1 |
| Chu, JS | 1 |
| Ho, WL | 1 |
| Ho, YS | 1 |
| Forgue-Lafitte, ME | 1 |
| Coudray, AM | 1 |
| Fagot, D | 1 |
| Mester, J | 1 |
4 other studies available for ketoconazole and Cancer of Colon
| Article | Year |
|---|---|
Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Topics: Anti-Bacterial Agents; Caco-2 Cells; Cell Movement; Cell Proliferation; Colonic Neoplasms; Gene Expr | 2016 |
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcitriol; Cell Line, Tumo | 2011 |
Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Pro | 2002 |
Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Breast Neoplasms; Cell | 1992 |