ketoconazole has been researched along with Burns in 8 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Standard burns were sequentially produced on the backs of Sprague-Dawley rats at 0, 1, 2, and 2 1/2 hr, followed by the IV injection of Evans blue dye." | 1.27 | Arachidonic acid metabolites mediate early burn edema. ( Alexander, F; Hechtman, HB; Huval, WV; Lelcuk, S; Mathieson, M; Shepro, D; Teoh, KH; Valeri, CR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Green, DP | 1 |
| Ruparel, S | 1 |
| Roman, L | 1 |
| Henry, MA | 1 |
| Hargreaves, KM | 1 |
| Jeschke, MG | 1 |
| Williams, FN | 1 |
| Finnerty, CC | 2 |
| Rodriguez, NA | 1 |
| Kulp, GA | 1 |
| Ferrando, A | 1 |
| Norbury, WB | 1 |
| Suman, OE | 1 |
| Kraft, R | 1 |
| Branski, LK | 1 |
| Al-mousawi, AM | 1 |
| Herndon, DN | 2 |
| Rojas, Y | 1 |
| Radhakrishnan, RS | 1 |
| Ferrando, AA | 1 |
| Wolfe, RR | 1 |
| Alexander, F | 1 |
| Mathieson, M | 1 |
| Teoh, KH | 1 |
| Huval, WV | 1 |
| Lelcuk, S | 1 |
| Valeri, CR | 1 |
| Shepro, D | 1 |
| Hechtman, HB | 1 |
| Still, JM | 1 |
| Law, EJ | 1 |
| Belcher, KE | 1 |
| Spencer, SA | 1 |
| Dubé, MP | 1 |
| Heseltine, PN | 1 |
| Rinaldi, MG | 1 |
| Evans, S | 1 |
| Zawacki, B | 1 |
| Proctor, KG | 1 |
| Shatkin, S | 1 |
| Kaminski, PM | 1 |
| Falck, JR | 1 |
| Capdevila, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Treatment of the Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation[NCT00675714] | Phase 2/Phase 3 | 1,126 participants (Actual) | Interventional | 2004-01-31 | Terminated (stopped due to At the request of the study site, this study has been closed and access to study-related data is unavailable. We are unable to submit the results-data.) | ||
| Assessment of Mechanisms of Improved Wound Healing of Anabolic Agents and Diet in Severely Burned Patients[NCT00673309] | Phase 2/Phase 3 | 644 participants (Actual) | Interventional | 2000-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ketoconazole and Burns
| Article | Year |
|---|---|
Burns: an update on current pharmacotherapy.
Topics: Adrenergic beta-Antagonists; Anabolic Agents; Animals; Burns; Growth Hormone; Humans; Hypoglycemic A | 2012 |
Restoration of hormonal action and muscle protein.
Topics: Arthroplasty, Replacement, Hip; Burns; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Insul | 2007 |
1 trial available for ketoconazole and Burns
| Article | Year |
|---|---|
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
Topics: 14-alpha Demethylase Inhibitors; Acute-Phase Proteins; Antifungal Agents; Body Composition; Burns; C | 2012 |
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
Topics: 14-alpha Demethylase Inhibitors; Acute-Phase Proteins; Antifungal Agents; Body Composition; Burns; C | 2012 |
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
Topics: 14-alpha Demethylase Inhibitors; Acute-Phase Proteins; Antifungal Agents; Body Composition; Burns; C | 2012 |
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
Topics: 14-alpha Demethylase Inhibitors; Acute-Phase Proteins; Antifungal Agents; Body Composition; Burns; C | 2012 |
5 other studies available for ketoconazole and Burns
| Article | Year |
|---|---|
Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury.
Topics: Animals; Behavior, Animal; Benzothiazoles; Burns; Chromatography, High Pressure Liquid; Hot Temperat | 2013 |
Arachidonic acid metabolites mediate early burn edema.
Topics: Animals; Body Water; Burns; Calcium Channel Blockers; Capillary Permeability; Chromones; Edema; Ibup | 1984 |
A comparison of susceptibility to five antifungal agents of yeast cultures from burn patients.
Topics: Amphotericin B; Antifungal Agents; Burns; Candida; Drug Resistance, Microbial; Fluconazole; Flucytos | 1995 |
Fungemia and colonization with nystatin-resistant Candida rugosa in a burn unit.
Topics: Amphotericin B; Burn Units; Burns; Candida; Candidiasis; Case-Control Studies; Cross Infection; Fluc | 1994 |
Modulation of arteriolar blood flow by inhibitors of arachidonic acid oxidation after thermal injury: possible role for a novel class of vasodilator metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Arterioles | 1988 |