Page last updated: 2024-10-29

ketoconazole and Blood Pressure, High

ketoconazole has been researched along with Blood Pressure, High in 21 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
"To determine the usefulness of ketoconazole for the control of arterial hypertension (AH) in Cushing syndrome (CS) as temporary treatment."7.70[Ketoconazole in the control of arterial hypertension in Cushing's syndrome]. ( Alvarez Barreiro, JA; Calvo Romero, JM; Díaz Pérez de Madrid, J; Morales Pérez, F, 1999)
"Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension."7.67Arterial hypertension as a complication of prolonged ketoconazole treatment. ( Astorga, R; García-Luna, PP; Gomez-Pan, A; Leal-Cerro, A; Miranda, ML; Pereira, JL; Villar, J, 1989)
"Our experience in the treatment of chronic mucocutaneous candidiasis with ketoconazole is reviewed."7.66Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients. ( Horsburgh, CR; Kirkpatrick, CH, 1983)
" There were 12 subjects with essential hypertension and 12 normotensive controls who received, after an initial control period, 48 h of treatment with a transdermal estradiol patch or ketoconazole tablets every 8 h for six doses, or in combination."5.06The effect of ketoconazole and transdermal estradiol on serum sex steroid hormones levels. ( Francom, SF; Hughes, GS; Ringer, TV; Spillers, CR, 1990)
"a) blood pressure levels normalized in most patients after remission of CS; b) ketoconazole was effective for the Control of HBP and seems to be a good indicator of post-surgical outcome, and c) higher age at presentation, longer duration of hypertension and higher systolic blood pressure figures before treatment negatively influence normalization of blood pressure after resolution of Cushing's syndrome."3.74Effect of hypercortisolism control on high blood pressure in Cushing's syndrome. ( Albiger, NM; Bruno, OD; Díaz, AG; Gómez, RM; Moncet, D; Pitoia, FA, 2007)
"To determine the usefulness of ketoconazole for the control of arterial hypertension (AH) in Cushing syndrome (CS) as temporary treatment."3.70[Ketoconazole in the control of arterial hypertension in Cushing's syndrome]. ( Alvarez Barreiro, JA; Calvo Romero, JM; Díaz Pérez de Madrid, J; Morales Pérez, F, 1999)
"Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension."3.67Arterial hypertension as a complication of prolonged ketoconazole treatment. ( Astorga, R; García-Luna, PP; Gomez-Pan, A; Leal-Cerro, A; Miranda, ML; Pereira, JL; Villar, J, 1989)
"Our experience in the treatment of chronic mucocutaneous candidiasis with ketoconazole is reviewed."3.66Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients. ( Horsburgh, CR; Kirkpatrick, CH, 1983)
"Pregnancy is a rare occurrence in women with Cushing's syndrome."2.38Cushing's syndrome and pregnancy. ( Aron, DC; Schnall, AM; Sheeler, LR, 1990)
"BLA = bilateral adrenalectomy CD = Cushing disease CS = Cushing syndrome eCRF = electronic case report form MRI = magnetic resonance imaging PCOS = polycystic ovary syndrome."1.46BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. ( Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS, 2017)
" Adrenolytic treatment with ketoconazole (400 mg daily) caused symptoms of adrenal insufficiency, but a reduced dosage of 200 mg daily lowered the cortisol level to between 5 and 11 micrograms/dl and normalized the blood pressure and clinical signs of Cushing's syndrome disappeared."1.29[Bilateral massive macronodular adrenal gland hyperplasia. A rare cause of Cushing's syndrome]. ( Allolio, B; Diehl, KL; Reincke, M; Strohm, M; Theiss, M, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's7 (33.33)18.2507
2000's5 (23.81)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geer, EB1
Shafiq, I1
Gordon, MB1
Bonert, V1
Ayala, A1
Swerdloff, RS1
Katznelson, L1
Lalazar, Y1
Manuylova, E1
Pulaski-Liebert, KJ1
Carmichael, JD1
Hannoush, Z1
Surampudi, V1
Broder, MS1
Cherepanov, D1
Eagan, M1
Lee, J1
Said, Q1
Neary, MP1
Biller, BMK1
Delivanis, DA1
Athimulam, S1
Bancos, I1
George, JC1
Vedamurthy, D1
Bermudez, M1
Kennedy, JW1
Izzedine, H1
Besse, B1
Lazareth, A1
Bourry, EF1
Soria, JC1
Brito, JP1
Singh, E1
Basu, A1
Barna, M1
Wilson, K1
Chiaruttini, R1
Muchowski, K1
Carmona-Bayonas, A1
Soler, IO1
Gómez, FI1
Billalabeitia, EG1
Saura, HP1
Tafalla, MS1
Díaz, MP1
Gómez, RM1
Albiger, NM1
Díaz, AG1
Moncet, D1
Pitoia, FA1
Bruno, OD1
Horsburgh, CR1
Kirkpatrick, CH1
Nichols, R1
Fallo, F1
Paoletta, A1
Tona, F1
Boscaro, M1
Sonino, N1
Strohm, M1
Reincke, M1
Theiss, M1
Diehl, KL1
Allolio, B1
Calvo Romero, JM1
Morales Pérez, F1
Alvarez Barreiro, JA1
Díaz Pérez de Madrid, J1
Neto, LS1
Filho, AG1
Bustorff-Silva, JM1
Köler, H1
Epelman, S1
Marini, SH1
Júnior, GG1
Rickman, T1
Garmany, R1
Doherty, T1
Benson, D1
Okusa, MD1
Hughes, GS1
Francom, SF1
Spillers, CR1
Ringer, TV1
Kiss, D1
Thiel, G1
Aron, DC1
Schnall, AM1
Sheeler, LR1
Leal-Cerro, A1
García-Luna, PP1
Villar, J1
Miranda, ML1
Pereira, JL1
Gomez-Pan, A1
Astorga, R1
Aabo, K1
De Coster, R1
Benito, P1
Corpas, MS1
Quesada, JM1
Jiménez, JA1

Reviews

2 reviews available for ketoconazole and Blood Pressure, High

ArticleYear
Concurrent illness and complications associated with canine hyperadrenocorticism.
    Seminars in veterinary medicine and surgery (small animal), 1994, Volume: 9, Issue:3

    Topics: Acute Disease; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; D

1994
Cushing's syndrome and pregnancy.
    American journal of obstetrics and gynecology, 1990, Volume: 162, Issue:1

    Topics: Adrenalectomy; Carbohydrate Metabolism; Cushing Syndrome; Female; Fetal Diseases; Humans; Hydrocorti

1990

Trials

1 trial available for ketoconazole and Blood Pressure, High

ArticleYear
The effect of ketoconazole and transdermal estradiol on serum sex steroid hormones levels.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:6

    Topics: Administration, Cutaneous; Adrenocorticotropic Hormone; Adult; Blood Pressure; Body Composition; Dru

1990

Other Studies

18 other studies available for ketoconazole and Blood Pressure, High

ArticleYear
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:8

    Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectom

2017
Modern Management of Mild Autonomous Cortisol Secretion.
    Clinical pharmacology and therapeutics, 2019, Volume: 106, Issue:6

    Topics: 14-alpha Demethylase Inhibitors; Adrenal Cortex Neoplasms; Adrenal Insufficiency; Adrenalectomy; Adr

2019
Quiz Page October 2016: Severe Hypokalemia, Metabolic Alkalosis, and Malignancy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 68, Issue:4

    Topics: ACTH Syndrome, Ectopic; Alkalosis; Amiloride; Cytochrome P-450 CYP3A Inhibitors; Diabetes Insipidus;

2016
Hypokalemia, metabolic alkalosis, and hypertension in a lung cancer patient.
    Kidney international, 2009, Volume: 76, Issue:1

    Topics: Aged; Alkalosis; Cushing Syndrome; France; Humans; Hypertension; Hypokalemia; Ketoconazole; Lung Neo

2009
Iatrogenic heart block during treatment of a patient with Cushing's syndrome: report of a case.
    Endocrine, 2012, Volume: 41, Issue:2

    Topics: Aged, 80 and over; Alkalosis; Antihypertensive Agents; Cushing Syndrome; Cytochrome P-450 CYP3A; Cyt

2012
Diagnostic puzzler: hypertension in teen.
    The Journal of family practice, 2012, Volume: 61, Issue:9

    Topics: Adenoma; Adolescent; Adrenal Glands; Antifungal Agents; Cushing Syndrome; Diagnosis, Differential; D

2012
Tailored hormonal therapy in secretory adrenocortical cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang

2007
Effect of hypercortisolism control on high blood pressure in Cushing's syndrome.
    Medicina, 2007, Volume: 67, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Antihypertensive Agents; Blood Pre

2007
Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients.
    The American journal of medicine, 1983, Jan-24, Volume: 74, Issue:1B

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis; Candidiasis, Chronic Mucocutaneous; Chemical and

1983
Response of hypertension to conventional antihypertensive treatment and/or steroidogenesis inhibitors in Cushing's syndrome.
    Journal of internal medicine, 1993, Volume: 234, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cushing Syndrome; Female; Humans; Hydrocortisone; Hy

1993
[Bilateral massive macronodular adrenal gland hyperplasia. A rare cause of Cushing's syndrome].
    Deutsche medizinische Wochenschrift (1946), 1994, Feb-11, Volume: 119, Issue:6

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotr

1994
[Ketoconazole in the control of arterial hypertension in Cushing's syndrome].
    Revista clinica espanola, 1999, Volume: 199, Issue:1

    Topics: Adult; Antihypertensive Agents; Cushing Syndrome; Drug Evaluation; Female; Humans; Hydrocortisone; H

1999
Pre-operative control of arterial hypertension using ketoconazole in pediatric patients with adrenocortical tumors.
    Journal of pediatric endocrinology & metabolism : JPEM, 2000, Volume: 13, Issue:2

    Topics: Adrenal Cortex Neoplasms; Child, Preschool; Humans; Hypertension; Infant; Ketoconazole; Male; Preope

2000
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:4

    Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Adrenocorticotropic Hormone; Aged; Alkalosis; Comorbidity; C

2001
Glucose-intolerance and prolonged renal-transplant insufficiency due to ketoconazole-cyclosporin A interaction.
    Clinical nephrology, 1990, Volume: 33, Issue:4

    Topics: Acute Kidney Injury; Adult; Blood Glucose; Creatinine; Cyclosporins; Drug Interactions; Female; Huma

1990
Arterial hypertension as a complication of prolonged ketoconazole treatment.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Chronic Disease; Cushing Syndrome; Female; Humans; Hypertension; Ketoconazole; Ma

1989
Hypertension during high-dose ketoconazole treatment: a probable mineralocorticosteroid effect.
    Lancet (London, England), 1987, Sep-12, Volume: 2, Issue:8559

    Topics: Blood Pressure; Humans; Hypertension; Ketoconazole; Male; Mineralocorticoids; Prostatic Neoplasms

1987
Control of hyperaldosteronism by ketoconazole.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:9

    Topics: Adult; Humans; Hyperaldosteronism; Hypertension; Ketoconazole; Male

1987