Page last updated: 2024-10-29

ketoconazole and Bladder, Overactive

ketoconazole has been researched along with Bladder, Overactive in 2 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
" Ten pharmacokinetic studies and three efficacy/safety studies in overactive bladder (OAB) patients were pooled for the population pharmacokinetic analysis."2.79Population pharmacokinetics of the 5-hydroxymethyl metabolite of tolterodine after administration of fesoterodine sustained release tablet in Western and East Asian populations. ( Malhotra, B; Oishi, M; Tomono, Y; Yamagami, H, 2014)
"Mirabegron is a moderate CYP2D6 inhibitor and weak CYP3A inhibitor."1.51Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug-Drug Interaction for Fesoterodine When Coadministered With Mirabegron. ( Goosen, TC; Lin, J; Malhotra, B; Tse, S; Yamagami, H, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, J1
Goosen, TC1
Tse, S1
Yamagami, H2
Malhotra, B2
Oishi, M1
Tomono, Y1

Trials

1 trial available for ketoconazole and Bladder, Overactive

ArticleYear
Population pharmacokinetics of the 5-hydroxymethyl metabolite of tolterodine after administration of fesoterodine sustained release tablet in Western and East Asian populations.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Benzhydryl Compounds; Creatinine; Cresols; Cytochrome

2014

Other Studies

1 other study available for ketoconazole and Bladder, Overactive

ArticleYear
Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug-Drug Interaction for Fesoterodine When Coadministered With Mirabegron.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:11

    Topics: Acetanilides; Adult; Benzhydryl Compounds; Cresols; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6

2019