ketoconazole has been researched along with Besnier-Boeck Disease in 10 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These data suggest that long-term use of ketoconazole may be a safe and effective alternative to corticosteroid treatment for sarcoid-associated hypercalcemia." | 5.28 | Treatment of sarcoidosis-associated hypercalcemia with ketoconazole. ( Bia, MJ; Insogna, K, 1991) |
| "Ketoconazole is an antifungal agent capable of inhibiting human steroid hormone synthesis, including renal 1,25-dihydroxyvitamin D [1,25-(OH)2D] synthesis." | 5.28 | Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia. ( Adams, JS; Diz, MM; Endres, DB; Sharma, OP, 1990) |
| "Sarcoidosis is generally treated with corticosteroids that are not always an effective therapy." | 2.73 | Antifungal treatment in sarcoidosis--a pilot intervention trial. ( Rott, T; Rylander, R; Tercelj, M, 2007) |
| " These data suggest that long-term use of ketoconazole may be a safe and effective alternative to corticosteroid treatment for sarcoid-associated hypercalcemia." | 1.28 | Treatment of sarcoidosis-associated hypercalcemia with ketoconazole. ( Bia, MJ; Insogna, K, 1991) |
| "Ketoconazole is an antifungal agent capable of inhibiting human steroid hormone synthesis, including renal 1,25-dihydroxyvitamin D [1,25-(OH)2D] synthesis." | 1.28 | Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia. ( Adams, JS; Diz, MM; Endres, DB; Sharma, OP, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walters, S | 1 |
| Bhatt, N | 1 |
| Medford, AR | 1 |
| da Mota, F | 1 |
| Murray, C | 1 |
| Ezzat, S | 1 |
| Tercelj, M | 1 |
| Rott, T | 1 |
| Rylander, R | 1 |
| Sturde, HC | 1 |
| Ejaz, AA | 1 |
| Zabaneh, RI | 1 |
| Tiwari, P | 1 |
| Nawab, ZM | 1 |
| Leehey, DJ | 1 |
| Ing, TS | 1 |
| Young, C | 1 |
| Burrows, R | 1 |
| Katz, J | 1 |
| Beynon, H | 1 |
| Bia, MJ | 1 |
| Insogna, K | 1 |
| Glass, AR | 1 |
| Cerletty, JM | 1 |
| Elliott, W | 1 |
| Lemann, J | 1 |
| Gray, RW | 1 |
| Eil, C | 1 |
| Adams, JS | 1 |
| Sharma, OP | 1 |
| Diz, MM | 1 |
| Endres, DB | 1 |
| Le, CT | 1 |
| Dennis, M | 1 |
1 trial available for ketoconazole and Besnier-Boeck Disease
| Article | Year |
|---|---|
Antifungal treatment in sarcoidosis--a pilot intervention trial.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antifungal Agents; Drug Therapy, Combination; Female; Fluconaz | 2007 |
9 other studies available for ketoconazole and Besnier-Boeck Disease
| Article | Year |
|---|---|
Reversible cerebellar signs due to sarcoid-related severe hypercalcaemia.
Topics: Chloroquine; Dehydration; Glucocorticoids; Humans; Hypercalcemia; Ketoconazole; Male; Mental Disorde | 2013 |
Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature.
Topics: Adrenalectomy; Adult; Anti-Infective Agents, Local; Antifungal Agents; Asthma; Autoimmune Diseases; | 2011 |
[Coccidioidomycosis in soldiers of the federal armed forces].
Topics: Adrenal Cortex Hormones; Adult; Amphotericin B; Coccidioidin; Coccidioidomycosis; Diagnosis, Differe | 1983 |
Ketoconazole in the treatment of recurrent nephrolithiasis associated with sarcoidosis.
Topics: Adult; Humans; Hypercalcemia; Ketoconazole; Kidney Calculi; Lymphatic Diseases; Male; Recurrence; Sa | 1994 |
Hypercalcaemia in sarcoidosis.
Topics: Adult; Diabetes Mellitus, Type 2; Diagnosis, Differential; Female; Humans; Hypercalcemia; Hyperparat | 1999 |
Treatment of sarcoidosis-associated hypercalcemia with ketoconazole.
Topics: Calcitriol; Calcium; Humans; Hypercalcemia; Ketoconazole; Kidney Failure, Chronic; Male; Middle Aged | 1991 |
Ketoconazole reduces elevated serum levels of 1,25-dihydroxyvitamin D in hypercalcemic sarcoidosis.
Topics: Adult; Calcifediol; Calcitriol; Calcium; Creatinine; Cyclic AMP; Humans; Hypercalcemia; Ketoconazole | 1990 |
Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia.
Topics: Adult; Calcitriol; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hypercalcemia | 1990 |
Adrenal mass in an immunocompromised man.
Topics: Abscess; Adrenal Gland Diseases; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Diagnosis, Di | 1988 |