Page last updated: 2024-10-29

ketoconazole and Autoimmune Disease

ketoconazole has been researched along with Autoimmune Disease in 9 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
"Ten patients with endogenous uveitis were in clinical remission attributable to treatment with cyclosporine and prednisone."9.07Combined use of cyclosporine and ketoconazole in the treatment of endogenous uveitis. ( Austin, HA; de Smet, MD; Lopez, JS; Nussenblatt, RB; Rubin, BI; Whitcup, SM, 1992)
"Ten patients with endogenous uveitis were in clinical remission attributable to treatment with cyclosporine and prednisone."5.07Combined use of cyclosporine and ketoconazole in the treatment of endogenous uveitis. ( Austin, HA; de Smet, MD; Lopez, JS; Nussenblatt, RB; Rubin, BI; Whitcup, SM, 1992)
"Ketoconazole was administered as a single daily oral dose of 200 mg to 12 patients with chronic mucocutaneous candidosis (CMC) of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED)."2.66Ketoconazole is effective against the chronic mucocutaneous candidosis of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED). ( Ahonen, P; Kahanpää, A; Myllärniemi, S; Perheentupa, J, 1986)
"Ketoconazole was effective in controlling symptoms of candidiasis in most patients."1.28Chronic mucocutaneous candidiasis in childhood and complications of non-Candida infection: a report of the Pediatric Immunodeficiency Collaborative Study Group. ( Herrod, HG, 1990)
"Systemic autoimmune diseases are generally treated with immunosuppressive agents."1.27Immunomodulation in autoimmune diseases. ( Fehér, J; Gergely, P; Gonzalez-Cabello, R; Láng, I, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mohamed, MF1
Jungerwirth, S1
Asatryan, A1
Jiang, P1
Othman, AA1
da Mota, F1
Murray, C1
Ezzat, S1
Appleboom, TM1
Flowers, FP1
de Smet, MD1
Rubin, BI1
Whitcup, SM1
Lopez, JS1
Austin, HA1
Nussenblatt, RB1
Herrod, HG1
Feuillan, P1
Poth, M1
Reilly, W1
Bright, G1
Loriaux, DL1
Chrousos, GP1
Naito, Y1
Yoshikawa, T1
Oyamada, H1
Tainaka, K1
Morita, Y1
Kogawa, T1
Sugino, S1
Kondo, M1
Gergely, P1
Láng, I1
Gonzalez-Cabello, R1
Fehér, J1
Ahonen, P1
Myllärniemi, S1
Kahanpää, A1
Perheentupa, J1

Trials

3 trials available for ketoconazole and Autoimmune Disease

ArticleYear
Assessment of effect of CYP3A inhibition, CYP induction, OATP1B inhibition, and high-fat meal on pharmacokinetics of the JAK1 inhibitor upadacitinib.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:10

    Topics: Adult; Area Under Curve; Autoimmune Diseases; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome

2017
Combined use of cyclosporine and ketoconazole in the treatment of endogenous uveitis.
    American journal of ophthalmology, 1992, Jun-15, Volume: 113, Issue:6

    Topics: Autoimmune Diseases; Cyclosporine; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies

1992
Ketoconazole is effective against the chronic mucocutaneous candidosis of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED).
    Acta medica Scandinavica, 1986, Volume: 220, Issue:4

    Topics: Adolescent; Adrenal Insufficiency; Adult; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Muc

1986

Other Studies

6 other studies available for ketoconazole and Autoimmune Disease

ArticleYear
Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Adrenalectomy; Adult; Anti-Infective Agents, Local; Antifungal Agents; Asthma; Autoimmune Diseases;

2011
Ketoconazole in the treatment of chronic mucocutaneous candidiasis secondary to autoimmune polyendocrinopathy-candidiasis syndrome.
    Cutis, 1982, Volume: 30, Issue:1

    Topics: Adolescent; Antifungal Agents; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Mucocutaneous;

1982
Chronic mucocutaneous candidiasis in childhood and complications of non-Candida infection: a report of the Pediatric Immunodeficiency Collaborative Study Group.
    The Journal of pediatrics, 1990, Volume: 116, Issue:3

    Topics: Adolescent; Amphotericin B; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Mucocutaneous; Ch

1990
Ketoconazole treatment of type 1 autoimmune polyglandular syndrome: effects on pituitary-adrenal axis.
    The Journal of pediatrics, 1986, Volume: 109, Issue:2

    Topics: Adrenocorticotropic Hormone; Autoimmune Diseases; Candidiasis, Oral; Child; Corticotropin-Releasing

1986
Esophageal candidiasis.
    Gastroenterologia Japonica, 1988, Volume: 23, Issue:4

    Topics: Amphotericin B; Autoimmune Diseases; Candidiasis; Esophageal Diseases; Esophagoscopy; Female; Humans

1988
Immunomodulation in autoimmune diseases.
    The Tokai journal of experimental and clinical medicine, 1986, Volume: 11 Suppl

    Topics: Adjuvants, Immunologic; Autoimmune Diseases; Drug Evaluation; Glutamine; Guanylthiourea; Humans; Imm

1986