ketoconazole has been researched along with Auricular Fibrillation in 3 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Excerpt | Relevance | Reference |
---|---|---|
"Rivaroxaban is indicated for stroke prevention in nonvalvular atrial fibrillation (AF)." | 3.91 | Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban. ( Chan, ECY; Cheong, EJY; Chua, DXY; Teo, DWX, 2019) |
" To evaluate drug-drug interactions, the impact of ketoconazole, a known strong inhibitor of cytochrome P450 3A4 and P-glycoprotein, was studied." | 2.90 | Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs. ( Burhenne, J; Foerster, KI; Haefeli, WE; Lehmann, ML; Mikus, G; Schaumaeker, M, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cheong, EJY | 1 |
Teo, DWX | 1 |
Chua, DXY | 1 |
Chan, ECY | 1 |
Mikus, G | 1 |
Foerster, KI | 1 |
Schaumaeker, M | 1 |
Lehmann, ML | 1 |
Burhenne, J | 1 |
Haefeli, WE | 1 |
1 trial available for ketoconazole and Auricular Fibrillation
Article | Year |
---|---|
Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs.
Topics: Administration, Oral; Adolescent; Adult; Atrial Fibrillation; Case-Control Studies; Chromatography, | 2019 |
2 other studies available for ketoconazole and Auricular Fibrillation
Article | Year |
---|---|
Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Atrial Fibrillation; Computer Simulation; D | 2019 |
Dofetilide for atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Ulcer Agents; An | 2000 |