Page last updated: 2024-10-29

ketoconazole and Auricular Fibrillation

ketoconazole has been researched along with Auricular Fibrillation in 3 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
"Rivaroxaban is indicated for stroke prevention in nonvalvular atrial fibrillation (AF)."3.91Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban. ( Chan, ECY; Cheong, EJY; Chua, DXY; Teo, DWX, 2019)
" To evaluate drug-drug interactions, the impact of ketoconazole, a known strong inhibitor of cytochrome P450 3A4 and P-glycoprotein, was studied."2.90Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs. ( Burhenne, J; Foerster, KI; Haefeli, WE; Lehmann, ML; Mikus, G; Schaumaeker, M, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheong, EJY1
Teo, DWX1
Chua, DXY1
Chan, ECY1
Mikus, G1
Foerster, KI1
Schaumaeker, M1
Lehmann, ML1
Burhenne, J1
Haefeli, WE1

Trials

1 trial available for ketoconazole and Auricular Fibrillation

ArticleYear
Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Atrial Fibrillation; Case-Control Studies; Chromatography,

2019

Other Studies

2 other studies available for ketoconazole and Auricular Fibrillation

ArticleYear
Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban.
    Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:11

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Atrial Fibrillation; Computer Simulation; D

2019
Dofetilide for atrial fibrillation.
    The Medical letter on drugs and therapeutics, 2000, May-15, Volume: 42, Issue:1078

    Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Ulcer Agents; An

2000