Page last updated: 2024-10-29

ketoconazole and Aspergillosis, Allergic Bronchopulmonary

ketoconazole has been researched along with Aspergillosis, Allergic Bronchopulmonary in 22 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Aspergillosis, Allergic Bronchopulmonary: Hypersensitivity reaction (ALLERGIC REACTION) to fungus ASPERGILLUS in an individual with long-standing BRONCHIAL ASTHMA. It is characterized by pulmonary infiltrates, EOSINOPHILIA, elevated serum IMMUNOGLOBULIN E, and skin reactivity to Aspergillus antigen.

Research Excerpts

ExcerptRelevanceReference
"A one year study of the efficacy of the antifungal agent ketoconazole in non-invasive pulmonary aspergillosis was carried out."9.06Trial of ketoconazole in non-invasive pulmonary aspergillosis. ( Faux, JA; Lane, DJ; Shale, DJ, 1987)
"A one year study of the efficacy of the antifungal agent ketoconazole in non-invasive pulmonary aspergillosis was carried out."5.06Trial of ketoconazole in non-invasive pulmonary aspergillosis. ( Faux, JA; Lane, DJ; Shale, DJ, 1987)
"We searched the Cochrane Airways Group Asthma trials register using the terms: (allergic bronchopulmonary aspergillosis OR aspergillosis OR allergic pulmonary aspergillosis OR allergic fungal and disease OR allergic mycotic and disease) AND (azole OR triazole OR itraconazole OR ketoconazole)."4.82Azoles for allergic bronchopulmonary aspergillosis associated with asthma. ( Gibson, PG; Wark, PA; Wilson, AJ, 2003)
"We searched the Cochrane Airways Group Asthma trials register using the terms: (allergic bronchopulmonary aspergillosis OR aspergillosis OR allergic pulmonary aspergillosis OR allergic fungal and disease OR allergic mycotic and disease) AND (azole OR triazole OR itraconazole OR ketoconazole)."4.82Azoles for allergic bronchopulmonary aspergillosis associated with asthma. ( Gibson, PG; Wark, PA; Wilson, AJ, 2004)
"The Cochrane Airways Group Asthma register was searched using the terms: (allergic bronchopulmonary aspergillosis OR aspergillosis OR allergic pulmonary aspergillosis OR allergic fungal and disease OR allergic mycotic and disease) AND (azole OR triazole OR itraconazole OR ketoconazole)."4.81Azoles for allergic bronchopulmonary aspergillosis associated with asthma. ( Gibson, PG; Wark, P; Wilson, AW, 2001)
" Three patients had underlying cystic fibrosis, and three had severe asthma; four of the six required continuous high-dose systemic prednisone (mean, 43 mg/day; confidence interval [CI], 23 to 63 mg/day) at the start of therapy."3.68Adjunctive therapy of allergic bronchopulmonary aspergillosis with itraconazole. ( Denning, DW; Lewiston, NJ; Stevens, DA; Van Wye, JE, 1991)
"Data are summarized on 6 patients with allergic bronchopulmonary aspergillosis, 5 of whom demonstrated marked improvement on therapy, and 12 patients with histoplasmosis including 8 with AIDS, 11 of whom responded and 1 recrudesced on therapy."1.28US experience with itraconazole in Aspergillus, Cryptococcus and Histoplasma infections in the immunocompromised host. ( Denning, DW; Hostetler, JS; Stevens, DA, 1992)
"Data is summarized on six patients with allergic bronchopulmonary aspergillosis, all of whom improved on therapy, and twelve patients with histoplasmosis including eight with AIDS, eleven of whom responded (three newly reported cases are included)."1.28[The treatment of aspergillosis, cryptococcosis and histoplasmosis in immunocompromised patients. Report of experience in the United States]. ( Hostetler, JS; Stevens, DA, 1991)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's12 (54.55)18.2507
2000's6 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wark, PA2
Gibson, PG4
Wilson, AJ2
Wark, P3
Braun, JJ1
Pauli, G1
de Blay, F1
Staib, F1
Mishra, SK1
Mannes, GP1
van der Heide, S1
van Aalderen, WM1
Gerritsen, J1
Lavrijsen, AP1
Balmus, KJ1
Nugteren-Huying, WM1
Roldaan, AC1
van 't Wout, JW1
Stricker, BH1
Pacheco, A1
Martin, JA1
Cuevas, M1
Wilson, AW2
Watkins, DN1
Badcock, NR1
Thompson, PJ1
Schmitt, HJ1
Edwards, F1
Andrade, J1
Niki, Y1
Armstrong, D1
Hiller, EJ1
Hostetler, JS2
Denning, DW2
Stevens, DA3
Schaberg, T1
Lode, H1
Georgiev, VS1
Van Wye, JE1
Lewiston, NJ1
van't Wout, JW1
Novakova, I1
Verhagen, CA1
Fibbe, WE1
de Pauw, BE1
van der Meer, JW1
De Beule, K1
De Doncker, P1
Cauwenbergh, G1
Koster, M1
Legendre, R1
Blatchford, N1
Daunas, J1
Chwetzoff, E1
Shale, DJ1
Faux, JA1
Lane, DJ1
Fournier, EC1

Reviews

7 reviews available for ketoconazole and Aspergillosis, Allergic Bronchopulmonary

ArticleYear
Azoles for allergic bronchopulmonary aspergillosis associated with asthma.
    The Cochrane database of systematic reviews, 2003, Issue:3

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Asthma; Controlled Clinical Trials as T

2003
Azoles for allergic bronchopulmonary aspergillosis associated with asthma.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Asthma; Humans; Itraconazole; Ketoconaz

2004
Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment.
    Respiratory medicine, 2004, Volume: 98, Issue:10

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Azoles; Evidence-Based Medicine; Foreca

2004
Azoles for allergic bronchopulmonary aspergillosis.
    The Cochrane database of systematic reviews, 2000, Issue:3

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Controlled Clinical Trials as Topic; Hu

2000
Azoles for allergic bronchopulmonary aspergillosis associated with asthma.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Asthma; Controlled Clinical Trials as T

2001
[Therapy of pulmonary mycoses].
    Deutsche medizinische Wochenschrift (1946), 1992, Nov-06, Volume: 117, Issue:45

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomy

1992
Treatment and developmental therapeutics in aspergillosis. 2. Azoles and other antifungal drugs.
    Respiration; international review of thoracic diseases, 1992, Volume: 59, Issue:5

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Azoles; Clotrim

1992

Trials

3 trials available for ketoconazole and Aspergillosis, Allergic Bronchopulmonary

ArticleYear
[Therapy of systemic mycoses in neutropenic patients using itraconazole. A comparative, randomized study with amphotericin B].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Volume: 86 Suppl 1

    Topics: Adolescent; Agranulocytosis; Amphotericin B; Antifungal Agents; Aspergillosis, Allergic Bronchopulmo

1991
The treatment of aspergillosis and aspergilloma with itraconazole, clinical results of an open international study (1982-1987).
    Mycoses, 1988, Volume: 31, Issue:9

    Topics: Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Chronic Disease; Clinical Trials as Topic;

1988
Trial of ketoconazole in non-invasive pulmonary aspergillosis.
    Thorax, 1987, Volume: 42, Issue:1

    Topics: Adult; Aged; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Clinica

1987

Other Studies

12 other studies available for ketoconazole and Aspergillosis, Allergic Bronchopulmonary

ArticleYear
[Allergic fungal sinusitis and allergic broncho-pulmonary aspergillosis: a fortuitous association or a nosological rhino-bronchial entity?].
    Revue des maladies respiratoires, 2005, Volume: 22, Issue:3

    Topics: Adult; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus; Combined Modality T

2005
[Ketoconazole in the treatment of pulmonary aspergillosis and aspergilloma: mycological observations (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, May-21, Volume: 107, Issue:20

    Topics: Adult; Aged; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Aspergillus

1982
Itraconazole and allergic bronchopulmonary aspergillosis in twin brothers with cystic fibrosis.
    Lancet (London, England), 1993, Feb-20, Volume: 341, Issue:8843

    Topics: Adolescent; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Cystic Fibrosis; Diseases i

1993
[Liver damage during administration of itraconazole (Trisporal)].
    Nederlands tijdschrift voor geneeskunde, 1993, Jan-02, Volume: 137, Issue:1

    Topics: Aged; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Chemical and Drug Induced Liver I

1993
Serologic response to itraconazole in allergic bronchopulmonary aspergillosis.
    Chest, 1993, Volume: 103, Issue:3

    Topics: Administration, Oral; Adult; Antibodies, Fungal; Antibody Specificity; Antifungal Agents; Aspergillo

1993
Itraconazole concentrations in airway fluid and tissue.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:2

    Topics: Adult; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Bronchoalveolar Lavage Fluid; Hu

1992
Comparison of azoles against aspergilli in vitro and in an experimental model of pulmonary aspergillosis.
    Chemotherapy, 1992, Volume: 38, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary;

1992
Aspergillosis.
    Journal of the Royal Society of Medicine, 1992, Volume: 85 Suppl 19

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Humans; Itracon

1992
US experience with itraconazole in Aspergillus, Cryptococcus and Histoplasma infections in the immunocompromised host.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antifungal Agents; Aspergillosis, Allergic Bronchop

1992
Adjunctive therapy of allergic bronchopulmonary aspergillosis with itraconazole.
    Chest, 1991, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Asthma; Cystic Fibro

1991
[The treatment of aspergillosis, cryptococcosis and histoplasmosis in immunocompromised patients. Report of experience in the United States].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Volume: 86 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Cry

1991
Trial of ketoconazole in allergic bronchopulmonary aspergillosis.
    Thorax, 1987, Volume: 42, Issue:10

    Topics: Aspergillosis, Allergic Bronchopulmonary; Humans; Ketoconazole; Male; Recurrence

1987