ketoconazole has been researched along with Apolipoprotein B-100, Familial Defective in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole is an imidazole derivative that is active as a broad-spectrum antifungal agent." | 1.30 | Effects of ketoconazole on plasma lipids and lipoprotein(a) in familial hypercholesterolaemia, compared with simvastatin. ( de Graaf, J; Stalenhoef, AF; Stuyt, PM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gylling, H | 2 |
| Vanhanen, H | 2 |
| Miettinen, TA | 4 |
| Stalenhoef, AF | 1 |
| Stuyt, PM | 1 |
| de Graaf, J | 1 |
| Kesäniemi, YA | 2 |
| Färkkilä, M | 1 |
| Koivisto, P | 1 |
| Vuoristo, M | 1 |
5 other studies available for ketoconazole and Apolipoprotein B-100, Familial Defective
| Article | Year |
|---|---|
Effects of ketoconazole on cholesterol precursors and low density lipoprotein kinetics in hypercholesterolemia.
Topics: Apolipoproteins B; Cholesterol; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; | 1993 |
Effects of ketoconazole on plasma lipids and lipoprotein(a) in familial hypercholesterolaemia, compared with simvastatin.
Topics: Adult; Aged; Anticholesteremic Agents; Antifungal Agents; Cholesterol; Dose-Response Relationship, D | 1997 |
Hypolipidemic effect and mechanism of ketoconazole without and with cholestyramine in familial hypercholesterolemia.
Topics: Adult; Cholesterol; Cholestyramine Resin; Desmosterol; Drug Therapy, Combination; Feces; Female; Hum | 1991 |
Inhibition of cholesterol absorption by neomycin, benzodiazepine derivatives and ketoconazole.
Topics: Anticholesteremic Agents; Benzodiazepines; Cholesterol; Humans; Hyperlipoproteinemia Type II; Intest | 1991 |
Enhanced cholesterol elimination and synthesis related to low-density lipoprotein metabolism.
Topics: Apolipoproteins B; Benzodiazepines; Bile Acids and Salts; Celiac Disease; Cholesterol; Diet; Feces; | 1987 |