ketoconazole has been researched along with Adrenocortical Hyperfunction in 10 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Adrenocortical Hyperfunction: Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole was a safe and effective option for treating dogs with PDH." | 1.35 | Use of ketoconazole to treat dogs with pituitary-dependent hyperadrenocorticism: 48 cases (1994-2007). ( Huang, HP; Lien, YH, 2008) |
| "Six to 10 months after hypercorticism was cured with ketoconazole and bilateral adrenalectomy, a thymic mass 2 to 5 cm in length was detected by computerized tomography or magnetic resonance imaging in all 3 patients." | 1.29 | [Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases]. ( Caillé, JM; Catargi, B; Drouillard, J; Greselle, JF; Laurent, F; Martigne, C; Roger, P; Tabarin, A, 1993) |
| " Adrenolytic treatment with ketoconazole (400 mg daily) caused symptoms of adrenal insufficiency, but a reduced dosage of 200 mg daily lowered the cortisol level to between 5 and 11 micrograms/dl and normalized the blood pressure and clinical signs of Cushing's syndrome disappeared." | 1.29 | [Bilateral massive macronodular adrenal gland hyperplasia. A rare cause of Cushing's syndrome]. ( Allolio, B; Diehl, KL; Reincke, M; Strohm, M; Theiss, M, 1994) |
| " Twenty dogs with hyperadrenocorticism (11 with PDH, 9 with adrenocortical tumor) were treated with ketoconazole at a dosage of 15 mg/kg given every 12 hours for a half month to 12 months." | 1.28 | Plasma cortisol response to ketoconazole administration in dogs with hyperadrenocorticism. ( Bruyette, DS; Farver, TB; Feldman, EC; Nelson, RW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yun, T | 1 |
| Koo, Y | 1 |
| Kim, S | 2 |
| Kim, H | 1 |
| Kang, JH | 1 |
| Yang, MP | 1 |
| Kang, BT | 1 |
| Lien, YH | 1 |
| Huang, HP | 1 |
| Dutta, D | 1 |
| Jain, R | 1 |
| Maisnam, I | 1 |
| Mishra, PK | 1 |
| Ghosh, S | 1 |
| Mukhopadhyay, S | 1 |
| Chowdhury, S | 1 |
| Brown, CG | 1 |
| Graves, TK | 1 |
| Tabarin, A | 1 |
| Catargi, B | 1 |
| Laurent, F | 1 |
| Greselle, JF | 1 |
| Martigne, C | 1 |
| Caillé, JM | 1 |
| Drouillard, J | 1 |
| Roger, P | 1 |
| Strohm, M | 1 |
| Reincke, M | 1 |
| Theiss, M | 1 |
| Diehl, KL | 1 |
| Allolio, B | 1 |
| Behrend, EN | 1 |
| Kemppainen, RJ | 1 |
| Clark, TP | 1 |
| Salman, MD | 1 |
| Peterson, ME | 1 |
| Khanderia, U | 1 |
| Nichols, R | 1 |
| Feldman, EC | 1 |
| Bruyette, DS | 1 |
| Nelson, RW | 1 |
| Farver, TB | 1 |
2 reviews available for ketoconazole and Adrenocortical Hyperfunction
| Article | Year |
|---|---|
Hyperadrenocorticism: treating dogs.
Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocortical Hyperfunction; Animals; Dihydrotestoste | 2007 |
Problems associated with medical therapy of canine hyperadrenocorticism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Animals; Cushing Syndrome; Diabetes Mellitus | 1990 |
8 other studies available for ketoconazole and Adrenocortical Hyperfunction
| Article | Year |
|---|---|
Combination therapy with azathioprine, cyclosporine and ketoconazole in a dog with concurrent pemphigus foliaceus and hyperadrenocorticism - Case report.
Topics: Adrenocortical Hyperfunction; Animals; Azathioprine; Cyclosporine; Dog Diseases; Dogs; Drug Combinat | 2020 |
Use of ketoconazole to treat dogs with pituitary-dependent hyperadrenocorticism: 48 cases (1994-2007).
Topics: Adrenal Cortex Function Tests; Adrenocortical Hyperfunction; Animals; Dog Diseases; Dogs; Female; Hy | 2008 |
Isolated Cushing's syndrome in early infancy due to left adrenal adenoma: an unusual aetiology.
Topics: 14-alpha Demethylase Inhibitors; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Ad | 2012 |
[Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases].
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adult; Carcinoid Tumor; Cushing Syndrome; Drug Therapy, | 1993 |
[Bilateral massive macronodular adrenal gland hyperplasia. A rare cause of Cushing's syndrome].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotr | 1994 |
Treatment of hyperadrenocorticism in dogs: a survey of internists and dermatologists.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; | 1999 |
Use of ketoconazole in the treatment of Cushing's syndrome.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Ketoconazole; R | 1991 |
Plasma cortisol response to ketoconazole administration in dogs with hyperadrenocorticism.
Topics: Adenoma; Administration, Oral; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Animals; Carc | 1990 |