ketoconazole has been researched along with Adrenal Cancer in 20 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "a) blood pressure levels normalized in most patients after remission of CS; b) ketoconazole was effective for the Control of HBP and seems to be a good indicator of post-surgical outcome, and c) higher age at presentation, longer duration of hypertension and higher systolic blood pressure figures before treatment negatively influence normalization of blood pressure after resolution of Cushing's syndrome." | 3.74 | Effect of hypercortisolism control on high blood pressure in Cushing's syndrome. ( Albiger, NM; Bruno, OD; Díaz, AG; Gómez, RM; Moncet, D; Pitoia, FA, 2007) |
| "To evaluate the efficacy of fluconazole as an alternative treatment for controlling hypercortisolism in Cushing's syndrome and to determine its effect on glucocorticoid production in vitro." | 3.73 | Long term control of hypercortisolism with fluconazole: case report and in vitro studies. ( Luger, A; Maier, C; Nowotny, P; Riedl, M; Schima, W; Zettinig, G, 2006) |
| "Modes of inhibition and binding of ketoconazole, an orally antimycotic agent, to NADPH-cytochrome P-450 dependent enzymes were investigated using subcellular fractions of human and rat testes, human adrenocortical adenoma tissue and rat adrenals and livers." | 3.67 | Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition. ( Higashi, Y; Inano, H; Omura, M; Oshima, H; Suzuki, K, 1987) |
| "About one third of patients with breast cancer show objective improvement with aminoglutethimide, and it may also be of use in the treatment of adrenal carcinoma." | 2.37 | Aminoglutethimide and ketoconazole: historical perspectives and future prospects. ( Nicholls, PJ; Shaw, MA; Smith, HJ, 1988) |
| "Ketoconazole was administered po in order to block adrenal steroidogenesis, the drug caused a remarkable fall of cortisol serum concentrations, but was unable to modify significantly the immunological pattern of the patient." | 1.28 | Hormonal and immunological pattern in a patient with acquired immunodeficiency syndrome related complex and Cushing's syndrome. ( De Mercato, R; Ghiggi, MR; Giuliani, M; Lombardi, G; Panza, N; Rezza, G; Rossi, R; Suligoi, B; Tommaselli, AP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biagetti, B | 1 |
| Simó-Servat, O | 1 |
| Ortiz-Z, A | 1 |
| Iglesias, C | 1 |
| Mesa, J | 1 |
| Corcuff, JB | 1 |
| Young, J | 1 |
| Masquefa-Giraud, P | 1 |
| Chanson, P | 1 |
| Baudin, E | 1 |
| Tabarin, A | 2 |
| Riedl, M | 1 |
| Maier, C | 1 |
| Zettinig, G | 1 |
| Nowotny, P | 1 |
| Schima, W | 1 |
| Luger, A | 1 |
| Gómez, RM | 1 |
| Albiger, NM | 1 |
| Díaz, AG | 1 |
| Moncet, D | 1 |
| Pitoia, FA | 1 |
| Bruno, OD | 1 |
| Engelhardt, D | 2 |
| Mann, K | 1 |
| Hörmann, R | 1 |
| Braun, S | 1 |
| Karl, HJ | 1 |
| Kintzer, PP | 1 |
| Peterson, ME | 1 |
| Luisetto, G | 1 |
| Zangari, M | 1 |
| Camozzi, V | 1 |
| Boscaro, M | 1 |
| Sonino, N | 1 |
| Fallo, F | 1 |
| Rossi, R | 1 |
| Tommaselli, AP | 1 |
| Panza, N | 1 |
| Ghiggi, MR | 1 |
| Rezza, G | 1 |
| Giuliani, M | 1 |
| Suligoi, B | 1 |
| De Mercato, R | 1 |
| Lombardi, G | 1 |
| Kong, HL | 1 |
| Lee, KO | 1 |
| Cheah, JS | 1 |
| Gilles, C | 1 |
| Navarranne, A | 1 |
| Parneix, M | 1 |
| Roger, P | 1 |
| Gregori, J | 1 |
| Ruiz Rivas, JL | 1 |
| Pascual, R | 1 |
| Palacios, C | 1 |
| Divers, MJ | 1 |
| Contreras, P | 2 |
| Rojas, A | 1 |
| Biagini, L | 1 |
| González, P | 1 |
| Massardo, T | 1 |
| Mesa Manteca, J | 1 |
| Boluda Monzó, S | 1 |
| Simó Canonge, R | 1 |
| Obiols Alfonso, G | 1 |
| Fève, B | 1 |
| Bauduceau, B | 1 |
| Lefebvre, H | 1 |
| Ritz, P | 1 |
| Garcin, JM | 1 |
| Gautier, D | 1 |
| Garciá-Girón, C | 1 |
| Artal, A | 1 |
| Garrido, P | 1 |
| González Barón, M | 1 |
| Weber, MM | 1 |
| Luppa, P | 1 |
| Shaw, MA | 1 |
| Nicholls, PJ | 1 |
| Smith, HJ | 1 |
| Higashi, Y | 1 |
| Omura, M | 1 |
| Suzuki, K | 1 |
| Inano, H | 1 |
| Oshima, H | 1 |
| Ravanal, M | 1 |
| Serón-Ferré, M | 1 |
2 reviews available for ketoconazole and Adrenal Cancer
| Article | Year |
|---|---|
Diagnosis and management of canine cortisol-secreting adrenal tumors.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antifungal A | 1997 |
Aminoglutethimide and ketoconazole: historical perspectives and future prospects.
Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Femal | 1988 |
18 other studies available for ketoconazole and Adrenal Cancer
| Article | Year |
|---|---|
Ectopic Cushing's syndrome: Paradoxical effect of somatostatin analogs.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adrenocorticotropic | 2017 |
Rapid control of severe neoplastic hypercortisolism with metyrapone and ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Cushing Synd | 2015 |
Long term control of hypercortisolism with fluconazole: case report and in vitro studies.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged, 80 and over; Antifungal Agents; Cell Line, Tu | 2006 |
Effect of hypercortisolism control on high blood pressure in Cushing's syndrome.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Antihypertensive Agents; Blood Pre | 2007 |
Ketoconazole inhibits cortisol secretion of an adrenal adenoma in vivo and in vitro.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Antifungal Agents; Humans; Hydrocorti | 1983 |
Recovery of bone mineral density after surgical cure, but not by ketoconazole treatment, in Cushing's syndrome.
Topics: Absorptiometry, Photon; Adenoma; Adrenal Gland Neoplasms; Adult; Bone Density; Cushing Syndrome; Dex | 2001 |
Hormonal and immunological pattern in a patient with acquired immunodeficiency syndrome related complex and Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; AIDS-Related Complex; Cushing Syndrome; Hum | 1992 |
Medical treatment of Cushing's syndrome with aminoglutethimide and ketoconazole.
Topics: Adenoma; Adrenal Gland Neoplasms; Aminoglutethimide; Cushing Syndrome; Humans; Hydrocortisone; Ketoc | 1992 |
[Use of ketoconazole in a case of malignant secreting adrenocortical adenoma].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Female; Humans; Ketoconazole | 1991 |
[Cushing's syndrome secondary to adrenal gland carcinoma controlled with ketoconazole].
Topics: Adrenal Gland Neoplasms; Aged; Carcinoma; Cushing Syndrome; Female; Humans; Ketoconazole | 1990 |
Ketoconazole treatment of Cushing's syndrome in pregnancy.
Topics: Adenoma; Adrenal Gland Neoplasms; Cushing Syndrome; Female; Humans; Ketoconazole; Pregnancy; Pregnan | 1990 |
Regression of metastatic adrenal carcinoma during palliative ketoconazole treatment.
Topics: Adrenal Gland Neoplasms; Female; Humans; Ketoconazole; Lung Neoplasms; Middle Aged; Palliative Care | 1985 |
[Ketoconazole in the treatment of adrenal carcinoma].
Topics: Adrenal Gland Neoplasms; Adult; Female; Humans; Ketoconazole; Palliative Care | 1989 |
[Value of ketoconazole in the treatment of Cushing's syndrome. Apropos of a case of adrenal polyadematosis].
Topics: Adenoma; Adrenal Gland Neoplasms; Cushing Syndrome; Humans; Ketoconazole; Male; Middle Aged | 1989 |
[Control of adrenal adenocarcinoma and Cushing's syndrome with ketoconazole].
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Humans; Ketoconazole; Male | 1989 |
Inhibition of human adrenal androgen secretion by ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Cushing Syndrome; Female | 1989 |
Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytoc | 1987 |
[Separation and characterization by high pressure liquid chromatography of delta(4)-3-ketosteroids synthetized from 3H-pregnenolone by an ectopic adrenal tumor treated with ketoconazole].
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; | 1987 |